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MBD3 (methyl-CpG binding domain protein 3)

Identity

Other names-
HGNC (Hugo) MBD3
LocusID (NCBI) 53615
Location 19p13.3
Location_base_pair Starts at 1576678 and ends at 1592652 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MBD3   6918
Entrez_Gene (NCBI)MBD3  53615  methyl-CpG binding domain protein 3
Cards
GeneCards (Weizmann)MBD3
Ensembl (Hinxton)ENSG00000071655 [Gene_View]  chr19:1576678-1592652 [Contig_View]  MBD3 [Vega]
AceView (NCBI)MBD3
Genatlas (Paris)MBD3
SOURCE (Stanford)NM_003926
Genomic and cartography
GoldenPath (UCSC)MBD3  -  19p13.3   chr19:1576678-1592652 -  19p13.3   [Description]    (hg19-Feb_2009)
EnsemblMBD3 - 19p13.3 [CytoView]
Mapping of homologs : NCBIMBD3 [Mapview]
OMIM603573   
Gene and transcription
Genbank (Entrez)AF072247 AK001474 AK021532 AK290882 BC000872
RefSeq transcript (SRS)NM_003926
RefSeq transcript (Entrez)NM_003926
RefSeq genomic (SRS)AC_000151 NC_000019 NC_018930 NG_029897 NT_011255 NW_001838476 NW_004078096
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NG_029897 NT_011255 NW_001838476 NW_004078096
Consensus coding sequences : CCDS (NCBI)MBD3
Cluster EST : UnigeneHs.178728 [ SRS ] Hs.178728 [ NCBI ]
CGAP (NCI)Hs.178728
Alternative Splicing : Fast-db (Paris)GSHG0015321
Alternative Splicing GalleryENSG00000071655
Gene ExpressionMBD3 [ NCBI-GEO ]   MBD3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95983 (SRS) O95983 (Uniprot)
NextProtO95983
With graphics : InterProO95983
Splice isoforms : SwissVarO95983(Swissvar)
Domaine pattern : Prosite (SRS)MBD (PS50982)   
Domaine pattern : Prosite (Expaxy)MBD (PS50982)   
Domains : Interpro (SRS)DNA-bd_integrase-typ    MeCpG-bd_2/3_C_dom    Methyl_CpG_DNA-bd   
Domains : Interpro (EBI)DNA-bd_integrase-typ    MeCpG-bd_2/3_C_dom    Methyl_CpG_DNA-bd   
Related proteins : CluSTrO95983
Domain families : Pfam (SRS)MBD (PF01429)    MBD_C (PF14048)   
Domain families : Pfam (Sanger)MBD (PF01429)    MBD_C (PF14048)   
Domain families : Pfam (NCBI)pfam01429    pfam14048   
Domain families : Smart (EMBL)MBD (SM00391)  
DMDM53615
Blocks (Seattle)O95983
Human Protein AtlasENSG00000071655
HPRD04653
IPIIPI00439194   IPI00439195   IPI00382954   
Protein Interaction databases
DIP (DOE-UCLA)O95983
IntAct (EBI)O95983
FunCoupENSG00000071655
REACTOMEMBD3
Protein Interaction Database53615
BioGRIDMBD3
InParanoidO95983
Interologous Interaction database O95983
IntegromeDBMBD3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MBD3
SNP (GeneSNP Utah)MBD3
SNP : HGBaseMBD3
Genetic variants : HAPMAPMBD3
Somatic Mutations in Cancer : COSMICMBD3 
CONAN: Copy Number AnalysisMBD3 
Mutations and Diseases : HGMDMBD3
OMIM603573   
GENETests603573   
Disease Genetic AssociationMBD3
Huge Navigator MBD3 [HugePedia]  MBD3 [HugeCancerGEM]
Genomic VariantsMBD3  MBD3 [DGVbeta]
ClinVarMBD3
snp3D : Map Gene to Disease53615
General knowledge
Homologs : HomoloGeneMBD3
Homology/Alignments : Family Browser (UCSC)MBD3
Phylogenetic Trees/Animal Genes : TreeFamMBD3
Chemical/Protein Interactions : CTD53615
Chemical/Pharm GKB GenePA30661
Clinical trialMBD3
Cancer Resource (Charite)ENSG00000071655
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  heterochromatin  in utero embryonic development  DNA binding  chromatin binding  protein binding  cytoplasm  methylation-dependent chromatin silencing  transcription, DNA-dependent  tissue development  histone acetylation  NuRD complex  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  heterochromatin  in utero embryonic development  DNA binding  chromatin binding  protein binding  cytoplasm  methylation-dependent chromatin silencing  transcription, DNA-dependent  tissue development  histone acetylation  NuRD complex  
Pathways : BIOCARTADownregulated of MTA-3 in ER-negative Breast Tumors [Genes]   
Other databases
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
PubGeneMBD3
iHOPMBD3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:33:11 CEST 2013
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