MBD3L2 (methyl-CpG binding domain protein 3 like 2)

2003-06-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 125997
MIM: 607964
HGNC: 18532
Ensembl: ENSG00000230522

Variants:

dbSNP: 125997
ClinVar: 125997
TCGA: ENSG00000230522
COSMIC: MBD3L2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000230522ENST00000381393Q8NHZ7

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
157016002005MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.14
232398762013Unique features of the anti-parallel, heterodimeric coiled-coil interaction between methyl-cytosine binding domain 2 (MBD2) homologues and GATA zinc finger domain containing 2A (GATAD2A/p66α).12
267699012016MBD3L2 promotes Tet2 enzymatic activity for mediating 5-methylcytosine oxidation.4

Citation

Dessen P

MBD3L2 (methyl-CpG binding domain protein 3 like 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41311/mbd3l2