Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MBD6 (methyl-CpG binding domain protein 6)

Identity

Alias_symbol (synonym)KIAA1887
Other alias-
HGNC (Hugo) MBD6
LocusID (NCBI) 114785
Atlas_Id 54444
Location 12q13.3  [Link to chromosome band 12q13]
Location_base_pair Starts at 57522876 and ends at 57530148 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CD74 (5q32) / MBD6 (12q13.3)MBD6 (12q13.3) / MYH14 (19q13.33)MBD6 (12q13.3) / SCARA3 (8p21.1)
MBD6 (12q13.3) / TLN1 (9p13.3)MYH14 (19q13.33) / MBD6 (12q13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MBD6   20445
Cards
Entrez_Gene (NCBI)MBD6  114785  methyl-CpG binding domain protein 6
Aliases
GeneCards (Weizmann)MBD6
Ensembl hg19 (Hinxton)ENSG00000166987 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166987 [Gene_View]  chr12:57522876-57530148 [Contig_View]  MBD6 [Vega]
ICGC DataPortalENSG00000166987
TCGA cBioPortalMBD6
AceView (NCBI)MBD6
Genatlas (Paris)MBD6
WikiGenes114785
SOURCE (Princeton)MBD6
Genetics Home Reference (NIH)MBD6
Genomic and cartography
GoldenPath hg38 (UCSC)MBD6  -     chr12:57522876-57530148 +  12q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MBD6  -     12q13.3   [Description]    (hg19-Feb_2009)
EnsemblMBD6 - 12q13.3 [CytoView hg19]  MBD6 - 12q13.3 [CytoView hg38]
Mapping of homologs : NCBIMBD6 [Mapview hg19]  MBD6 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB067474 AK056399 AK093078 AK296990 AL834230
RefSeq transcript (Entrez)NM_052897
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MBD6
Cluster EST : UnigeneHs.524523 [ NCBI ]
CGAP (NCI)Hs.524523
Alternative Splicing GalleryENSG00000166987
Gene ExpressionMBD6 [ NCBI-GEO ]   MBD6 [ EBI - ARRAY_EXPRESS ]   MBD6 [ SEEK ]   MBD6 [ MEM ]
Gene Expression Viewer (FireBrowse)MBD6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114785
GTEX Portal (Tissue expression)MBD6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96DN6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96DN6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96DN6
Splice isoforms : SwissVarQ96DN6
PhosPhoSitePlusQ96DN6
Domaine pattern : Prosite (Expaxy)MBD (PS50982)   
Domains : Interpro (EBI)DNA-bd_dom    Methyl_CpG_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)MBD (SM00391)  
Conserved Domain (NCBI)MBD6
DMDM Disease mutations114785
Blocks (Seattle)MBD6
SuperfamilyQ96DN6
Human Protein AtlasENSG00000166987
Peptide AtlasQ96DN6
HPRD11296
IPIIPI00073730   IPI00910653   IPI00465019   IPI01022825   IPI01022676   IPI01021037   IPI01020876   IPI01021336   IPI01022311   IPI01021675   IPI01021995   IPI01021827   
Protein Interaction databases
DIP (DOE-UCLA)Q96DN6
IntAct (EBI)Q96DN6
FunCoupENSG00000166987
BioGRIDMBD6
STRING (EMBL)MBD6
ZODIACMBD6
Ontologies - Pathways
QuickGOQ96DN6
Ontology : AmiGOfibrillar center  DNA binding  chromatin binding  nucleus  nucleoplasm  nucleoplasm  chromocenter  protein deubiquitination  
Ontology : EGO-EBIfibrillar center  DNA binding  chromatin binding  nucleus  nucleoplasm  nucleoplasm  chromocenter  protein deubiquitination  
NDEx NetworkMBD6
Atlas of Cancer Signalling NetworkMBD6
Wikipedia pathwaysMBD6
Orthology - Evolution
OrthoDB114785
GeneTree (enSembl)ENSG00000166987
Phylogenetic Trees/Animal Genes : TreeFamMBD6
HOVERGENQ96DN6
HOGENOMQ96DN6
Homologs : HomoloGeneMBD6
Homology/Alignments : Family Browser (UCSC)MBD6
Gene fusions - Rearrangements
Fusion : MitelmanCD74/MBD6 [5q32/12q13.3]  [t(5;12)(q33;q13)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMBD6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MBD6
dbVarMBD6
ClinVarMBD6
1000_GenomesMBD6 
Exome Variant ServerMBD6
ExAC (Exome Aggregation Consortium)MBD6 (select the gene name)
Genetic variants : HAPMAP114785
Genomic Variants (DGV)MBD6 [DGVbeta]
DECIPHERMBD6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMBD6 
Mutations
ICGC Data PortalMBD6 
TCGA Data PortalMBD6 
Broad Tumor PortalMBD6
OASIS PortalMBD6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMBD6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMBD6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MBD6
DgiDB (Drug Gene Interaction Database)MBD6
DoCM (Curated mutations)MBD6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MBD6 (select a term)
intoGenMBD6
Cancer3DMBD6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenMBD6
Genetic Testing Registry MBD6
NextProtQ96DN6 [Medical]
TSGene114785
GENETestsMBD6
Target ValidationMBD6
Huge Navigator MBD6 [HugePedia]
snp3D : Map Gene to Disease114785
BioCentury BCIQMBD6
ClinGenMBD6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114785
Chemical/Pharm GKB GenePA134866196
Clinical trialMBD6
Miscellaneous
canSAR (ICR)MBD6 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMBD6
EVEXMBD6
GoPubMedMBD6
iHOPMBD6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:42:29 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.