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MBIP (MAP3K12 binding inhibitory protein 1)

Identity

Other alias-
HGNC (Hugo) MBIP
LocusID (NCBI) 51562
Atlas_Id 54445
Location 14q13.3  [Link to chromosome band 14q13]
Location_base_pair Starts at 36767764 and ends at 36789882 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AXL (19q13.2) / MBIP (14q13.3)MBIP (14q13.3) / LINC01599 (14q21.3)MBIP (14q13.3) / PCLO (7q21.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Lung: Translocations in Adenocarcinoma
Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)MBIP   20427
Cards
Entrez_Gene (NCBI)MBIP  51562  MAP3K12 binding inhibitory protein 1
Aliases
GeneCards (Weizmann)MBIP
Ensembl hg19 (Hinxton)ENSG00000151332 [Gene_View]  chr14:36767764-36789882 [Contig_View]  MBIP [Vega]
Ensembl hg38 (Hinxton)ENSG00000151332 [Gene_View]  chr14:36767764-36789882 [Contig_View]  MBIP [Vega]
ICGC DataPortalENSG00000151332
TCGA cBioPortalMBIP
AceView (NCBI)MBIP
Genatlas (Paris)MBIP
WikiGenes51562
SOURCE (Princeton)MBIP
Genetics Home Reference (NIH)MBIP
Genomic and cartography
GoldenPath hg19 (UCSC)MBIP  -     chr14:36767764-36789882 -  14q13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MBIP  -     14q13.3   [Description]    (hg38-Dec_2013)
EnsemblMBIP - 14q13.3 [CytoView hg19]  MBIP - 14q13.3 [CytoView hg38]
Mapping of homologs : NCBIMBIP [Mapview hg19]  MBIP [Mapview hg38]
OMIM609431   
Gene and transcription
Genbank (Entrez)AA761503 AB038523 AF208857 AK293473 AK315290
RefSeq transcript (Entrez)NM_001144891 NM_001308110 NM_016586
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)MBIP
Cluster EST : UnigeneHs.368647 [ NCBI ]
CGAP (NCI)Hs.368647
Alternative Splicing GalleryENSG00000151332
Gene ExpressionMBIP [ NCBI-GEO ]   MBIP [ EBI - ARRAY_EXPRESS ]   MBIP [ SEEK ]   MBIP [ MEM ]
Gene Expression Viewer (FireBrowse)MBIP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51562
GTEX Portal (Tissue expression)MBIP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS73   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS73  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS73
Splice isoforms : SwissVarQ9NS73
PhosPhoSitePlusQ9NS73
Domains : Interpro (EBI)MBIP   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)MBIP
DMDM Disease mutations51562
Blocks (Seattle)MBIP
SuperfamilyQ9NS73
Human Protein AtlasENSG00000151332
Peptide AtlasQ9NS73
HPRD14368
IPIIPI00009868   IPI00940922   IPI00410048   IPI00410047   IPI01024817   IPI01025071   IPI01026320   IPI01026208   IPI01026509   
Protein Interaction databases
DIP (DOE-UCLA)Q9NS73
IntAct (EBI)Q9NS73
FunCoupENSG00000151332
BioGRIDMBIP
STRING (EMBL)MBIP
ZODIACMBIP
Ontologies - Pathways
QuickGOQ9NS73
Ontology : AmiGOinactivation of MAPK activity involved in osmosensory signaling pathway  protein kinase inhibitor activity  protein binding  nucleus  Ada2/Gcn5/Ada3 transcription activator complex  nucleolus  cytoplasm  identical protein binding  histone H3 acetylation  
Ontology : EGO-EBIinactivation of MAPK activity involved in osmosensory signaling pathway  protein kinase inhibitor activity  protein binding  nucleus  Ada2/Gcn5/Ada3 transcription activator complex  nucleolus  cytoplasm  identical protein binding  histone H3 acetylation  
NDEx NetworkMBIP
Atlas of Cancer Signalling NetworkMBIP
Wikipedia pathwaysMBIP
Orthology - Evolution
OrthoDB51562
GeneTree (enSembl)ENSG00000151332
Phylogenetic Trees/Animal Genes : TreeFamMBIP
HOVERGENQ9NS73
HOGENOMQ9NS73
Homologs : HomoloGeneMBIP
Homology/Alignments : Family Browser (UCSC)MBIP
Gene fusions - Rearrangements
Fusion : MitelmanAXL/MBIP [19q13.2/14q13.3]  [t(14;19)(q13;q13)]  
Fusion : MitelmanMBIP/C14orf183 [14q13.3/t(14;14)(q13;q21)]  
Fusion Cancer (Beijing)AXL [19q13.2]  -  MBIP [14q13.3]  [FUSC003133]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMBIP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MBIP
dbVarMBIP
ClinVarMBIP
1000_GenomesMBIP 
Exome Variant ServerMBIP
ExAC (Exome Aggregation Consortium)MBIP (select the gene name)
Genetic variants : HAPMAP51562
Genomic Variants (DGV)MBIP [DGVbeta]
DECIPHER (Syndromes)14:36767764-36789882  ENSG00000151332
CONAN: Copy Number AnalysisMBIP 
Mutations
ICGC Data PortalMBIP 
TCGA Data PortalMBIP 
Broad Tumor PortalMBIP
OASIS PortalMBIP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMBIP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMBIP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MBIP
DgiDB (Drug Gene Interaction Database)MBIP
DoCM (Curated mutations)MBIP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MBIP (select a term)
intoGenMBIP
Cancer3DMBIP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609431   
Orphanet
MedgenMBIP
Genetic Testing Registry MBIP
NextProtQ9NS73 [Medical]
TSGene51562
GENETestsMBIP
Huge Navigator MBIP [HugePedia]
snp3D : Map Gene to Disease51562
BioCentury BCIQMBIP
ClinGenMBIP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51562
Chemical/Pharm GKB GenePA134929415
Clinical trialMBIP
Miscellaneous
canSAR (ICR)MBIP (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMBIP
EVEXMBIP
GoPubMedMBIP
iHOPMBIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:14:41 CET 2017

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