| Nomenclature | | HGNC (Hugo) | MBL2 6922 |
| Cards | | Entrez_Gene (NCBI) | MBL2 4153 mannose-binding lectin (protein C) 2, soluble |
| GeneCards (Weizmann) | MBL2 |
| Ensembl (Hinxton) | ENSG00000165471 [Gene_View] chr10:54525140-54531460 [Contig_View] MBL2 [Vega] |
| ICGC DataPortal | ENSG00000165471 |
| cBioPortal | MBL2 |
| AceView (NCBI) | MBL2 |
| Genatlas (Paris) | MBL2 |
| WikiGenes | 4153 |
| SOURCE (Princeton) | NM_000242 |
| Genomic and cartography | | GoldenPath (UCSC) | MBL2 - 10q21.1 chr10:54525140-54531460 - 10q21.1 [Description] (hg19-Feb_2009) |
| Ensembl | MBL2 - 10q21.1 [CytoView] |
| Mapping of homologs : NCBI | MBL2 [Mapview] |
| OMIM | 154545 614372 |
| Gene and transcription |
| Genbank (Entrez) | AF360991 AY826184 BC069338 BC096179 BC096180 |
| RefSeq transcript (Entrez) | NM_000242 |
| RefSeq genomic (Entrez) | AC_000142 NC_000010 NC_018921 NG_008196 NT_030059 NW_001837985 NW_004929376 |
| Consensus coding sequences : CCDS (NCBI) | MBL2 |
| Cluster EST : Unigene | Hs.499674 [ NCBI ] |
| CGAP (NCI) | Hs.499674 |
| Alternative Splicing : Fast-db (Paris) | GSHG0004086 |
| Alternative Splicing Gallery | ENSG00000165471 |
| Gene Expression | MBL2 [ NCBI-GEO ] MBL2 [ SEEK ] MBL2 [ MEM ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P11226 (Uniprot) |
| NextProt | P11226 [Medical] |
| With graphics : InterPro | P11226 |
| Splice isoforms : SwissVar | P11226 (Swissvar) |
| Domaine pattern : Prosite (Expaxy) | C_TYPE_LECTIN_1 (PS00615) C_TYPE_LECTIN_2 (PS50041) |
| Domains : Interpro (EBI) | C-type_lectin [organisation] C-type_lectin-like [organisation] C-type_lectin_CS [organisation] C-type_lectin_fold [organisation] Collagen [organisation] |
| Related proteins : CluSTr | P11226 |
| Domain families : Pfam (Sanger) | Collagen (PF01391) Lectin_C (PF00059) |
| Domain families : Pfam (NCBI) | pfam01391 pfam00059 |
| Domain families : Smart (EMBL) | CLECT (SM00034) |
| DMDM Disease mutations | 4153 |
| Blocks (Seattle) | P11226 |
| PDB (SRS) | 1HUP |
| PDB (PDBSum) | 1HUP |
| PDB (IMB) | 1HUP |
| PDB (RSDB) | 1HUP |
| Human Protein Atlas | ENSG00000165471 [gene] [tissue] [antibody] [cell] [cancer] |
| Peptide Atlas | P11226 |
| HPRD | 01107 |
| IPI | IPI00004373 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P11226 |
| IntAct (EBI) | P11226 |
| FunCoup | ENSG00000165471 |
| BioGRID | MBL2 |
| InParanoid | P11226 |
| Interologous Interaction database | P11226 |
| IntegromeDB | MBL2 |
| STRING (EMBL) | MBL2 |
| Ontologies - Pathways | | Ontology : AmiGO | complement activation, lectin pathway complement activation, lectin pathway complement activation, lectin pathway receptor binding protein binding mannose binding mannose binding mannose binding extracellular region collagen trimer extracellular space acute-phase response complement activation complement activation, classical pathway response to oxidative stress opsonization cell surface defense response to bacterium negative regulation of growth of symbiont in host innate immune response innate immune response calcium-dependent protein binding negative regulation of viral process positive regulation of phagocytosis defense response to Gram-positive bacterium killing by host of symbiont cells |
| Ontology : EGO-EBI | complement activation, lectin pathway complement activation, lectin pathway complement activation, lectin pathway receptor binding protein binding mannose binding mannose binding mannose binding extracellular region collagen trimer extracellular space acute-phase response complement activation complement activation, classical pathway response to oxidative stress opsonization cell surface defense response to bacterium negative regulation of growth of symbiont in host innate immune response innate immune response calcium-dependent protein binding negative regulation of viral process positive regulation of phagocytosis defense response to Gram-positive bacterium killing by host of symbiont cells |
| Pathways : BIOCARTA | Lectin Induced Complement Pathway [Genes] Complement Pathway [Genes] |
| Pathways : KEGG | Phagosome Complement and coagulation cascades Staphylococcus aureus infection |
| Protein Interaction Database | MBL2 |
| Wikipedia pathways | MBL2 |
| Gene fusion - rearrangments | | Polymorphisms : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | MBL2 |
| snp3D : Map Gene to Disease | 4153 |
| SNP (GeneSNP Utah) | MBL2 |
| SNP : HGBase | MBL2 |
| Genetic variants : HAPMAP | MBL2 |
| Exome Variant | MBL2 |
| 1000_Genomes | MBL2 |
| ICGC program | ENSG00000165471 |
| Somatic Mutations in Cancer : COSMIC | MBL2 |
| CONAN: Copy Number Analysis | MBL2 |
| Mutations and Diseases : HGMD | MBL2 |
| Genomic Variants | MBL2 MBL2 [DGVbeta] |
| dbVar | MBL2 |
| ClinVar | MBL2 |
| Pred. of missenses | PolyPhen-2 SIFT(SG) SIFT(JCVI) Align-GVGD MutAssessor Mutanalyser |
| Pred. splices | GeneSplicer Human Splicing Finder MaxEntScan |
| Diseases | | OMIM | 154545 614372 |
| Medgen | MBL2 |
| GENETests | MBL2 |
| Disease Genetic Association | MBL2 |
| Huge Navigator |
MBL2 [HugePedia] MBL2 [HugeCancerGEM] |
| General knowledge |
|---|
| Homologs : HomoloGene | MBL2 |
| Homology/Alignments : Family Browser (UCSC) | MBL2 |
| Phylogenetic Trees/Animal Genes : TreeFam | MBL2 |
| Chemical/Protein Interactions : CTD | 4153 |
| Chemical/Pharm GKB Gene | PA30665 |
| Clinical trial | MBL2 |
| Cancer Resource (Charite) | ENSG00000165471 |
| Other databases | | Probes |
|---|
| Litterature | | PubMed | 499 Pubmed reference(s) in Entrez |
| CoreMine | MBL2 |
| iHOP | MBL2 |
| OncoSearch | MBL2 |
