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MBOAT1 (membrane bound O-acyltransferase domain containing 1)

Identity

Alias_namesOACT1
O-acyltransferase (membrane bound) domain containing 1
Alias_symbol (synonym)MGC44669
dJ434O11.1
LPEAT1
Other aliasLPLAT
LPLAT 1
LPSAT
HGNC (Hugo) MBOAT1
LocusID (NCBI) 154141
Atlas_Id 68835
Location 6p22.3  [Link to chromosome band 6p22]
Location_base_pair Starts at 20099686 and ends at 20212464 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HGSNAT (8p11.21) / MBOAT1 (6p22.3)MBOAT1 (6p22.3) / FYN (6q21)MBOAT1 (6p22.3) / RPL37 (5p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(6;6)(p22;q21) MBOAT1/FYN
t(6;8)(p22;p11) HGSNAT/MBOAT1


External links

Nomenclature
HGNC (Hugo)MBOAT1   21579
Cards
Entrez_Gene (NCBI)MBOAT1  154141  membrane bound O-acyltransferase domain containing 1
AliasesLPEAT1; LPLAT; LPLAT; LPSAT; 
OACT1; dJ434O11.1
GeneCards (Weizmann)MBOAT1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr6:20099686-20212464 [Contig_View]  MBOAT1 [Vega]
TCGA cBioPortalMBOAT1
AceView (NCBI)MBOAT1
Genatlas (Paris)MBOAT1
WikiGenes154141
SOURCE (Princeton)MBOAT1
Genetics Home Reference (NIH)MBOAT1
Genomic and cartography
GoldenPath hg38 (UCSC)MBOAT1  -     chr6:20099686-20212464 -  6p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MBOAT1  -     6p22.3   [Description]    (hg19-Feb_2009)
EnsemblMBOAT1 - 6p22.3 [CytoView hg19]  MBOAT1 - 6p22.3 [CytoView hg38]
Mapping of homologs : NCBIMBOAT1 [Mapview hg19]  MBOAT1 [Mapview hg38]
OMIM611732   
Gene and transcription
Genbank (Entrez)AB305043 AK093994 AK131269 AK296857 AK304748
RefSeq transcript (Entrez)NM_001080480
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MBOAT1
Cluster EST : UnigeneHs.377830 [ NCBI ]
CGAP (NCI)Hs.377830
Gene ExpressionMBOAT1 [ NCBI-GEO ]   MBOAT1 [ EBI - ARRAY_EXPRESS ]   MBOAT1 [ SEEK ]   MBOAT1 [ MEM ]
Gene Expression Viewer (FireBrowse)MBOAT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)154141
GTEX Portal (Tissue expression)MBOAT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZNC8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZNC8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZNC8
Splice isoforms : SwissVarQ6ZNC8
Catalytic activity : Enzyme2.3.1.- [ Enzyme-Expasy ]   2.3.1.-2.3.1.- [ IntEnz-EBI ]   2.3.1.- [ BRENDA ]   2.3.1.- [ KEGG ]   
PhosPhoSitePlusQ6ZNC8
Domains : Interpro (EBI)MBOAT_fam   
Domain families : Pfam (Sanger)MBOAT (PF03062)   
Domain families : Pfam (NCBI)pfam03062   
Conserved Domain (NCBI)MBOAT1
DMDM Disease mutations154141
Blocks (Seattle)MBOAT1
SuperfamilyQ6ZNC8
Peptide AtlasQ6ZNC8
IPIIPI00374294   IPI00927767   IPI00924444   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZNC8
IntAct (EBI)Q6ZNC8
BioGRIDMBOAT1
STRING (EMBL)MBOAT1
ZODIACMBOAT1
Ontologies - Pathways
QuickGOQ6ZNC8
Ontology : AmiGO###############################################################################################################################################################################################################################################################              
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################              
NDEx NetworkMBOAT1
Atlas of Cancer Signalling NetworkMBOAT1
Wikipedia pathwaysMBOAT1
Orthology - Evolution
OrthoDB154141
Phylogenetic Trees/Animal Genes : TreeFamMBOAT1
HOVERGENQ6ZNC8
HOGENOMQ6ZNC8
Homologs : HomoloGeneMBOAT1
Homology/Alignments : Family Browser (UCSC)MBOAT1
Gene fusions - Rearrangements
Fusion : QuiverMBOAT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMBOAT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MBOAT1
dbVarMBOAT1
ClinVarMBOAT1
1000_GenomesMBOAT1 
Exome Variant ServerMBOAT1
Genetic variants : HAPMAP154141
Genomic Variants (DGV)MBOAT1 [DGVbeta]
DECIPHERMBOAT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMBOAT1 
Mutations
ICGC Data PortalMBOAT1 
TCGA Data PortalMBOAT1 
Broad Tumor PortalMBOAT1
OASIS PortalMBOAT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMBOAT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMBOAT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MBOAT1
DgiDB (Drug Gene Interaction Database)MBOAT1
DoCM (Curated mutations)MBOAT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MBOAT1 (select a term)
intoGenMBOAT1
Cancer3DMBOAT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611732   
Orphanet
DisGeNETMBOAT1
MedgenMBOAT1
Genetic Testing Registry MBOAT1
NextProtQ6ZNC8 [Medical]
TSGene154141
GENETestsMBOAT1
Target ValidationMBOAT1
Huge Navigator MBOAT1 [HugePedia]
snp3D : Map Gene to Disease154141
BioCentury BCIQMBOAT1
ClinGenMBOAT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD154141
Chemical/Pharm GKB GenePA134979205
Clinical trialMBOAT1
Miscellaneous
canSAR (ICR)MBOAT1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMBOAT1
EVEXMBOAT1
GoPubMedMBOAT1
iHOPMBOAT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:39:14 CET 2018

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