Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MBOAT2 (membrane bound O-acyltransferase domain containing 2)

Identity

Alias (NCBI)LPAAT
LPCAT
LPCAT4
LPEAT
LPLAT 2
OACT2
HGNC (Hugo) MBOAT2
HGNC Alias symbFLJ14415
FLJ90298
HGNC Previous nameOACT2
HGNC Previous nameO-acyltransferase (membrane bound) domain containing 2
LocusID (NCBI) 129642
Atlas_Id 53023
Location 2p25.1  [Link to chromosome band 2p25]
Location_base_pair Starts at 8852690 and ends at 9003684 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FABP2 (4q26) / MBOAT2 (2p25.1)IDH1 (2q34) / MBOAT2 (2p25.1)MBOAT2 (2p25.1) / ARHGAP25 (2p13.3)
MBOAT2 (2p25.1) / BRAT1 (7p22.3)MBOAT2 (2p25.1) / PRKCE (2p21)PRKCE (2p21) / MBOAT2 (2p25.1)
MBOAT2 2p25.1 / PRKCE 2p21MBOAT2 2p25.1 / ARHGAP25 2p13.3MBOAT2 2p25.1 / BRAT1 7p22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MBOAT2   25193
Cards
Entrez_Gene (NCBI)MBOAT2    membrane bound O-acyltransferase domain containing 2
AliasesLPAAT; LPCAT; LPCAT4; LPEAT; 
LPLAT; OACT2
GeneCards (Weizmann)MBOAT2
Ensembl hg19 (Hinxton)ENSG00000143797 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143797 [Gene_View]  ENSG00000143797 [Sequence]  chr2:8852690-9003684 [Contig_View]  MBOAT2 [Vega]
ICGC DataPortalENSG00000143797
TCGA cBioPortalMBOAT2
AceView (NCBI)MBOAT2
Genatlas (Paris)MBOAT2
SOURCE (Princeton)MBOAT2
Genetics Home Reference (NIH)MBOAT2
Genomic and cartography
GoldenPath hg38 (UCSC)MBOAT2  -     chr2:8852690-9003684 -  2p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MBOAT2  -     2p25.1   [Description]    (hg19-Feb_2009)
GoldenPathMBOAT2 - 2p25.1 [CytoView hg19]  MBOAT2 - 2p25.1 [CytoView hg38]
ImmunoBaseENSG00000143797
Genome Data Viewer NCBIMBOAT2 [Mapview hg19]  
OMIM611949   
Gene and transcription
Genbank (Entrez)AB305044 AF052107 AK027321 AK074779 AK295907
RefSeq transcript (Entrez)NM_001321265 NM_001321266 NM_001321267 NM_138799
Consensus coding sequences : CCDS (NCBI)MBOAT2
Gene ExpressionMBOAT2 [ NCBI-GEO ]   MBOAT2 [ EBI - ARRAY_EXPRESS ]   MBOAT2 [ SEEK ]   MBOAT2 [ MEM ]
Gene Expression Viewer (FireBrowse)MBOAT2 [ Firebrowse - Broad ]
GenevisibleExpression of MBOAT2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)129642
GTEX Portal (Tissue expression)MBOAT2
Human Protein AtlasENSG00000143797-MBOAT2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZWT7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZWT7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZWT7
PhosPhoSitePlusQ6ZWT7
Domains : Interpro (EBI)MBOAT_fam   
Domain families : Pfam (Sanger)MBOAT (PF03062)   
Domain families : Pfam (NCBI)pfam03062   
Conserved Domain (NCBI)MBOAT2
SuperfamilyQ6ZWT7
AlphaFold pdb e-kbQ6ZWT7   
Human Protein Atlas [tissue]ENSG00000143797-MBOAT2 [tissue]
HPRD11410
Protein Interaction databases
DIP (DOE-UCLA)Q6ZWT7
IntAct (EBI)Q6ZWT7
BioGRIDMBOAT2
STRING (EMBL)MBOAT2
ZODIACMBOAT2
Ontologies - Pathways
QuickGOQ6ZWT7
Ontology : AmiGO1-acylglycerol-3-phosphate O-acyltransferase activity  endoplasmic reticulum membrane  endoplasmic reticulum membrane  phospholipid biosynthetic process  membrane  integral component of membrane  acyltransferase activity  lipid modification  regulation of chondrocyte differentiation  phosphatidylserine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  1-acylglycerophosphocholine O-acyltransferase activity  1-acylglycerophosphoethanolamine O-acyltransferase activity  1-acylglycerophosphoserine O-acyltransferase activity  
Ontology : EGO-EBI1-acylglycerol-3-phosphate O-acyltransferase activity  endoplasmic reticulum membrane  endoplasmic reticulum membrane  phospholipid biosynthetic process  membrane  integral component of membrane  acyltransferase activity  lipid modification  regulation of chondrocyte differentiation  phosphatidylserine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  1-acylglycerophosphocholine O-acyltransferase activity  1-acylglycerophosphoethanolamine O-acyltransferase activity  1-acylglycerophosphoserine O-acyltransferase activity  
Pathways : KEGGGlycerolipid metabolism    Glycerophospholipid metabolism   
NDEx NetworkMBOAT2
Atlas of Cancer Signalling NetworkMBOAT2
Wikipedia pathwaysMBOAT2
Orthology - Evolution
OrthoDB129642
GeneTree (enSembl)ENSG00000143797
Phylogenetic Trees/Animal Genes : TreeFamMBOAT2
Homologs : HomoloGeneMBOAT2
Homology/Alignments : Family Browser (UCSC)MBOAT2
Gene fusions - Rearrangements
Fusion : MitelmanMBOAT2/ARHGAP25 [2p25.1/2p13.3]  
Fusion : MitelmanMBOAT2/BRAT1 [2p25.1/7p22.3]  
Fusion : MitelmanMBOAT2/PRKCE [2p25.1/2p21]  
Fusion : QuiverMBOAT2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMBOAT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MBOAT2
dbVarMBOAT2
ClinVarMBOAT2
MonarchMBOAT2
1000_GenomesMBOAT2 
Exome Variant ServerMBOAT2
GNOMAD BrowserENSG00000143797
Varsome BrowserMBOAT2
ACMGMBOAT2 variants
VarityQ6ZWT7
Genomic Variants (DGV)MBOAT2 [DGVbeta]
DECIPHERMBOAT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMBOAT2 
Mutations
ICGC Data PortalMBOAT2 
TCGA Data PortalMBOAT2 
Broad Tumor PortalMBOAT2
OASIS PortalMBOAT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMBOAT2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMBOAT2
Mutations and Diseases : HGMDMBOAT2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMBOAT2
DgiDB (Drug Gene Interaction Database)MBOAT2
DoCM (Curated mutations)MBOAT2
CIViC (Clinical Interpretations of Variants in Cancer)MBOAT2
Cancer3DMBOAT2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611949   
Orphanet
DisGeNETMBOAT2
MedgenMBOAT2
Genetic Testing Registry MBOAT2
NextProtQ6ZWT7 [Medical]
GENETestsMBOAT2
Target ValidationMBOAT2
Huge Navigator MBOAT2 [HugePedia]
ClinGenMBOAT2
Clinical trials, drugs, therapy
MyCancerGenomeMBOAT2
Protein Interactions : CTDMBOAT2
Pharm GKB GenePA134987740
PharosQ6ZWT7
Clinical trialMBOAT2
Miscellaneous
canSAR (ICR)MBOAT2
HarmonizomeMBOAT2
DataMed IndexMBOAT2
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMBOAT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:18:00 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.