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MC5R (melanocortin 5 receptor)

Identity

Other aliasMC2
HGNC (Hugo) MC5R
LocusID (NCBI) 4161
Atlas_Id 68837
Location 18p11.21  [Link to chromosome band 18p11]
Location_base_pair Starts at 13825543 and ends at 13826861 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MC5R   6933
Cards
Entrez_Gene (NCBI)MC5R  4161  melanocortin 5 receptor
AliasesMC2
GeneCards (Weizmann)MC5R
Ensembl hg19 (Hinxton)ENSG00000176136 [Gene_View]  chr18:13825543-13826861 [Contig_View]  MC5R [Vega]
Ensembl hg38 (Hinxton)ENSG00000176136 [Gene_View]  chr18:13825543-13826861 [Contig_View]  MC5R [Vega]
ICGC DataPortalENSG00000176136
TCGA cBioPortalMC5R
AceView (NCBI)MC5R
Genatlas (Paris)MC5R
WikiGenes4161
SOURCE (Princeton)MC5R
Genetics Home Reference (NIH)MC5R
Genomic and cartography
GoldenPath hg19 (UCSC)MC5R  -     chr18:13825543-13826861 +  18p11.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MC5R  -     18p11.21   [Description]    (hg38-Dec_2013)
EnsemblMC5R - 18p11.21 [CytoView hg19]  MC5R - 18p11.21 [CytoView hg38]
Mapping of homologs : NCBIMC5R [Mapview hg19]  MC5R [Mapview hg38]
OMIM600042   
Gene and transcription
Genbank (Entrez)BC069153 BC069545 BC095531
RefSeq transcript (Entrez)NM_005913
RefSeq genomic (Entrez)NC_000018 NC_018929 NT_010859 NW_004929409
Consensus coding sequences : CCDS (NCBI)MC5R
Cluster EST : UnigeneHs.248145 [ NCBI ]
CGAP (NCI)Hs.248145
Alternative Splicing GalleryENSG00000176136
Gene ExpressionMC5R [ NCBI-GEO ]   MC5R [ EBI - ARRAY_EXPRESS ]   MC5R [ SEEK ]   MC5R [ MEM ]
Gene Expression Viewer (FireBrowse)MC5R [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4161
GTEX Portal (Tissue expression)MC5R
Protein : pattern, domain, 3D structure
UniProt/SwissProtP33032   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP33032  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP33032
Splice isoforms : SwissVarP33032
PhosPhoSitePlusP33032
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Melancort_rcpt    Melancort_rcpt_5    Melcrt_ACTH_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)MC5R
DMDM Disease mutations4161
Blocks (Seattle)MC5R
SuperfamilyP33032
Human Protein AtlasENSG00000176136
Peptide AtlasP33032
HPRD08965
IPIIPI00012299   
Protein Interaction databases
DIP (DOE-UCLA)P33032
IntAct (EBI)P33032
FunCoupENSG00000176136
BioGRIDMC5R
STRING (EMBL)MC5R
ZODIACMC5R
Ontologies - Pathways
QuickGOP33032
Ontology : AmiGOmelanocortin receptor activity  protein binding  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  positive regulation of cAMP biosynthetic process  hormone binding  
Ontology : EGO-EBImelanocortin receptor activity  protein binding  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  positive regulation of cAMP biosynthetic process  hormone binding  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkMC5R
Atlas of Cancer Signalling NetworkMC5R
Wikipedia pathwaysMC5R
Orthology - Evolution
OrthoDB4161
GeneTree (enSembl)ENSG00000176136
Phylogenetic Trees/Animal Genes : TreeFamMC5R
HOVERGENP33032
HOGENOMP33032
Homologs : HomoloGeneMC5R
Homology/Alignments : Family Browser (UCSC)MC5R
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMC5R [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MC5R
dbVarMC5R
ClinVarMC5R
1000_GenomesMC5R 
Exome Variant ServerMC5R
ExAC (Exome Aggregation Consortium)MC5R (select the gene name)
Genetic variants : HAPMAP4161
Genomic Variants (DGV)MC5R [DGVbeta]
DECIPHER (Syndromes)18:13825543-13826861  ENSG00000176136
CONAN: Copy Number AnalysisMC5R 
Mutations
ICGC Data PortalMC5R 
TCGA Data PortalMC5R 
Broad Tumor PortalMC5R
OASIS PortalMC5R [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMC5R  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMC5R
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MC5R
DgiDB (Drug Gene Interaction Database)MC5R
DoCM (Curated mutations)MC5R (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MC5R (select a term)
intoGenMC5R
Cancer3DMC5R(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600042   
Orphanet
MedgenMC5R
Genetic Testing Registry MC5R
NextProtP33032 [Medical]
TSGene4161
GENETestsMC5R
Huge Navigator MC5R [HugePedia]
snp3D : Map Gene to Disease4161
BioCentury BCIQMC5R
ClinGenMC5R
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4161
Chemical/Pharm GKB GenePA30677
Clinical trialMC5R
Miscellaneous
canSAR (ICR)MC5R (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMC5R
EVEXMC5R
GoPubMedMC5R
iHOPMC5R
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:27:49 CET 2017

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