MCAT (malonyl-CoA-acyl carrier protein transacylase)

2014-11-01  

Identity

HGNC
LOCATION
22q13.2
LOCUSID
ALIAS
FASN2C,MCT,MCT1,MT,NET62,fabD
FUSION GENES

Other Information

Locus ID:

NCBI: 27349
MIM: 614479
HGNC: 29622
Ensembl: ENSG00000100294

Variants:

dbSNP: 27349
ClinVar: 27349
TCGA: ENSG00000100294
COSMIC: MCAT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100294ENST00000290429Q8IVS2
ENSG00000100294ENST00000327555Q8IVS2
ENSG00000100294ENST00000608052V9GYY6

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Fatty acid biosynthesisKEGGko00061
Fatty acid biosynthesisKEGGhsa00061
Metabolic pathwaysKEGGhsa01100
Fatty acid biosynthesis, initiationKEGGM00082
Fatty acid metabolismKEGGhsa01212
Fatty acid metabolismKEGGko01212
Fatty acid biosynthesis, initiationKEGGhsa_M00082
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Mitochondrial Fatty Acid Beta-OxidationREACTOMER-HSA-77289

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
197677532009Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.225
205643192010Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.36
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17

Citation

Dessen P

MCAT (malonyl-CoA-acyl carrier protein transacylase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68838/mcat