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MCAT (malonyl-CoA-acyl carrier protein transacylase)

Identity

Alias_namesmalonyl CoA:ACP acyltransferase (mitochondrial)
Alias_symbol (synonym)MT
MCT
fabD
FASN2C
NET62
Other aliasMCT1
HGNC (Hugo) MCAT
LocusID (NCBI) 27349
Atlas_Id 68838
Location 22q13.2  [Link to chromosome band 22q13]
Location_base_pair Starts at 43132206 and ends at 43143397 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PRPF8 (17p13.3) / MCAT (22q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MCAT   29622
Cards
Entrez_Gene (NCBI)MCAT  27349  malonyl-CoA-acyl carrier protein transacylase
AliasesFASN2C; MCT; MCT1; MT; 
NET62; fabD
GeneCards (Weizmann)MCAT
Ensembl hg19 (Hinxton)ENSG00000100294 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100294 [Gene_View]  chr22:43132206-43143397 [Contig_View]  MCAT [Vega]
ICGC DataPortalENSG00000100294
TCGA cBioPortalMCAT
AceView (NCBI)MCAT
Genatlas (Paris)MCAT
WikiGenes27349
SOURCE (Princeton)MCAT
Genetics Home Reference (NIH)MCAT
Genomic and cartography
GoldenPath hg38 (UCSC)MCAT  -     chr22:43132206-43143397 -  22q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MCAT  -     22q13.2   [Description]    (hg19-Feb_2009)
EnsemblMCAT - 22q13.2 [CytoView hg19]  MCAT - 22q13.2 [CytoView hg38]
Mapping of homologs : NCBIMCAT [Mapview hg19]  MCAT [Mapview hg38]
OMIM614479   
Gene and transcription
Genbank (Entrez)AA402283 AI811069 AK314059 AL359401 AL359403
RefSeq transcript (Entrez)NM_014507 NM_173467
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MCAT
Cluster EST : UnigeneHs.349111 [ NCBI ]
CGAP (NCI)Hs.349111
Alternative Splicing GalleryENSG00000100294
Gene ExpressionMCAT [ NCBI-GEO ]   MCAT [ EBI - ARRAY_EXPRESS ]   MCAT [ SEEK ]   MCAT [ MEM ]
Gene Expression Viewer (FireBrowse)MCAT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27349
GTEX Portal (Tissue expression)MCAT
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IVS2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IVS2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IVS2
Splice isoforms : SwissVarQ8IVS2
Catalytic activity : Enzyme2.3.1.39 [ Enzyme-Expasy ]   2.3.1.392.3.1.39 [ IntEnz-EBI ]   2.3.1.39 [ BRENDA ]   2.3.1.39 [ KEGG ]   
PhosPhoSitePlusQ8IVS2
Domains : Interpro (EBI)Ac_transferase_dom    Acyl_transferase    Acyl_Trfase/lysoPLipase    Malonyl_transacylase_ACP-bd    PKS_acyl_transferase   
Domain families : Pfam (Sanger)Acyl_transf_1 (PF00698)   
Domain families : Pfam (NCBI)pfam00698   
Domain families : Smart (EMBL)PKS_AT (SM00827)  
Conserved Domain (NCBI)MCAT
DMDM Disease mutations27349
Blocks (Seattle)MCAT
PDB (SRS)2C2N   
PDB (PDBSum)2C2N   
PDB (IMB)2C2N   
PDB (RSDB)2C2N   
Structural Biology KnowledgeBase2C2N   
SCOP (Structural Classification of Proteins)2C2N   
CATH (Classification of proteins structures)2C2N   
SuperfamilyQ8IVS2
Human Protein AtlasENSG00000100294
Peptide AtlasQ8IVS2
HPRD14786
IPIIPI00023359   IPI00163960   
Protein Interaction databases
DIP (DOE-UCLA)Q8IVS2
IntAct (EBI)Q8IVS2
FunCoupENSG00000100294
BioGRIDMCAT
STRING (EMBL)MCAT
ZODIACMCAT
Ontologies - Pathways
QuickGOQ8IVS2
Ontology : AmiGORNA binding  [acyl-carrier-protein] S-malonyltransferase activity  [acyl-carrier-protein] S-malonyltransferase activity  mitochondrion  mitochondrial matrix  fatty acid biosynthetic process  fatty acid biosynthetic process  fatty acid beta-oxidation  metabolic process  transferase activity  
Ontology : EGO-EBIRNA binding  [acyl-carrier-protein] S-malonyltransferase activity  [acyl-carrier-protein] S-malonyltransferase activity  mitochondrion  mitochondrial matrix  fatty acid biosynthetic process  fatty acid biosynthetic process  fatty acid beta-oxidation  metabolic process  transferase activity  
Pathways : KEGGFatty acid biosynthesis   
NDEx NetworkMCAT
Atlas of Cancer Signalling NetworkMCAT
Wikipedia pathwaysMCAT
Orthology - Evolution
OrthoDB27349
GeneTree (enSembl)ENSG00000100294
Phylogenetic Trees/Animal Genes : TreeFamMCAT
HOVERGENQ8IVS2
HOGENOMQ8IVS2
Homologs : HomoloGeneMCAT
Homology/Alignments : Family Browser (UCSC)MCAT
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMCAT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MCAT
dbVarMCAT
ClinVarMCAT
1000_GenomesMCAT 
Exome Variant ServerMCAT
ExAC (Exome Aggregation Consortium)MCAT (select the gene name)
Genetic variants : HAPMAP27349
Genomic Variants (DGV)MCAT [DGVbeta]
DECIPHERMCAT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMCAT 
Mutations
ICGC Data PortalMCAT 
TCGA Data PortalMCAT 
Broad Tumor PortalMCAT
OASIS PortalMCAT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMCAT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMCAT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MCAT
DgiDB (Drug Gene Interaction Database)MCAT
DoCM (Curated mutations)MCAT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MCAT (select a term)
intoGenMCAT
Cancer3DMCAT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614479   
Orphanet
MedgenMCAT
Genetic Testing Registry MCAT
NextProtQ8IVS2 [Medical]
TSGene27349
GENETestsMCAT
Target ValidationMCAT
Huge Navigator MCAT [HugePedia]
snp3D : Map Gene to Disease27349
BioCentury BCIQMCAT
ClinGenMCAT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27349
Chemical/Pharm GKB GenePA162395058
Clinical trialMCAT
Miscellaneous
canSAR (ICR)MCAT (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMCAT
EVEXMCAT
GoPubMedMCAT
iHOPMCAT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:25:38 CEST 2017

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