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MCHR1 (melanin concentrating hormone receptor 1)

Identity

Alias_namesGPR24
G protein-coupled receptor 24
melanin-concentrating hormone receptor 1
Alias_symbol (synonym)SLC1
MCH1R
Other aliasMCH-1R
SLC-1
HGNC (Hugo) MCHR1
LocusID (NCBI) 2847
Atlas_Id 56204
Location 22q13.2  [Link to chromosome band 22q13]
Location_base_pair Starts at 40679178 and ends at 40682814 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EP300 (22q13.2) / MCHR1 (22q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MCHR1   4479
Cards
Entrez_Gene (NCBI)MCHR1  2847  melanin concentrating hormone receptor 1
AliasesGPR24; MCH-1R; MCH1R; SLC-1; 
SLC1
GeneCards (Weizmann)MCHR1
Ensembl hg19 (Hinxton)ENSG00000128285 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128285 [Gene_View]  chr22:40679178-40682814 [Contig_View]  MCHR1 [Vega]
ICGC DataPortalENSG00000128285
TCGA cBioPortalMCHR1
AceView (NCBI)MCHR1
Genatlas (Paris)MCHR1
WikiGenes2847
SOURCE (Princeton)MCHR1
Genetics Home Reference (NIH)MCHR1
Genomic and cartography
GoldenPath hg38 (UCSC)MCHR1  -     chr22:40679178-40682814 +  22q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MCHR1  -     22q13.2   [Description]    (hg19-Feb_2009)
EnsemblMCHR1 - 22q13.2 [CytoView hg19]  MCHR1 - 22q13.2 [CytoView hg38]
Mapping of homologs : NCBIMCHR1 [Mapview hg19]  MCHR1 [Mapview hg38]
OMIM601751   
Gene and transcription
Genbank (Entrez)AB063174 AF490537 AI934819 AK308739 AK314857
RefSeq transcript (Entrez)NM_005297
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MCHR1
Cluster EST : UnigeneHs.248122 [ NCBI ]
CGAP (NCI)Hs.248122
Alternative Splicing GalleryENSG00000128285
Gene ExpressionMCHR1 [ NCBI-GEO ]   MCHR1 [ EBI - ARRAY_EXPRESS ]   MCHR1 [ SEEK ]   MCHR1 [ MEM ]
Gene Expression Viewer (FireBrowse)MCHR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2847
GTEX Portal (Tissue expression)MCHR1
Human Protein AtlasENSG00000128285-MCHR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99705   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99705  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99705
Splice isoforms : SwissVarQ99705
PhosPhoSitePlusQ99705
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    MCH1_rcpt    MCH_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)MCHR1
DMDM Disease mutations2847
Blocks (Seattle)MCHR1
SuperfamilyQ99705
Human Protein Atlas [tissue]ENSG00000128285-MCHR1 [tissue]
Peptide AtlasQ99705
HPRD11874
IPIIPI00017705   IPI00552549   
Protein Interaction databases
DIP (DOE-UCLA)Q99705
IntAct (EBI)Q99705
FunCoupENSG00000128285
BioGRIDMCHR1
STRING (EMBL)MCHR1
ZODIACMCHR1
Ontologies - Pathways
QuickGOQ99705
Ontology : AmiGOG-protein coupled receptor activity  plasma membrane  integral component of plasma membrane  generation of precursor metabolites and energy  G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  chemical synaptic transmission  feeding behavior  neuropeptide receptor activity  melanin-concentrating hormone receptor activity  non-motile cilium  
Ontology : EGO-EBIG-protein coupled receptor activity  plasma membrane  integral component of plasma membrane  generation of precursor metabolites and energy  G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  chemical synaptic transmission  feeding behavior  neuropeptide receptor activity  melanin-concentrating hormone receptor activity  non-motile cilium  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkMCHR1
Atlas of Cancer Signalling NetworkMCHR1
Wikipedia pathwaysMCHR1
Orthology - Evolution
OrthoDB2847
GeneTree (enSembl)ENSG00000128285
Phylogenetic Trees/Animal Genes : TreeFamMCHR1
HOVERGENQ99705
HOGENOMQ99705
Homologs : HomoloGeneMCHR1
Homology/Alignments : Family Browser (UCSC)MCHR1
Gene fusions - Rearrangements
Tumor Fusion PortalMCHR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMCHR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MCHR1
dbVarMCHR1
ClinVarMCHR1
1000_GenomesMCHR1 
Exome Variant ServerMCHR1
ExAC (Exome Aggregation Consortium)ENSG00000128285
GNOMAD BrowserENSG00000128285
Genetic variants : HAPMAP2847
Genomic Variants (DGV)MCHR1 [DGVbeta]
DECIPHERMCHR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMCHR1 
Mutations
ICGC Data PortalMCHR1 
TCGA Data PortalMCHR1 
Broad Tumor PortalMCHR1
OASIS PortalMCHR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMCHR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMCHR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MCHR1
DgiDB (Drug Gene Interaction Database)MCHR1
DoCM (Curated mutations)MCHR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MCHR1 (select a term)
intoGenMCHR1
Cancer3DMCHR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601751   
Orphanet
DisGeNETMCHR1
MedgenMCHR1
Genetic Testing Registry MCHR1
NextProtQ99705 [Medical]
TSGene2847
GENETestsMCHR1
Target ValidationMCHR1
Huge Navigator MCHR1 [HugePedia]
snp3D : Map Gene to Disease2847
BioCentury BCIQMCHR1
ClinGenMCHR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2847
Chemical/Pharm GKB GenePA28867
Clinical trialMCHR1
Miscellaneous
canSAR (ICR)MCHR1 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMCHR1
EVEXMCHR1
GoPubMedMCHR1
iHOPMCHR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:21:54 CET 2017

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