Identity |
Alias (NCBI) | BCL2L3 | EAT | MCL1-ES | MCL1L | MCL1S | Mcl-1 | TM | bcl2-L-3 | mcl1/EAT |
HGNC (Hugo) | MCL1 |
HGNC Alias symb | BCL2L3 | Mcl-1 |
HGNC Previous name | myeloid cell leukemia sequence 1 (BCL2-related) | myeloid cell leukemia 1 | MCL1, BCL2 family apoptosis regulator |
LocusID (NCBI) | 4170 |
Atlas_Id | 41317 |
Location | 1q21.2 [Link to chromosome band 1q21] |
Location_base_pair | Starts at 150574551 and ends at 150579738 bp from pter ( according to hg38-Dec_2013) |
Fusion genes (updated 2017) | Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands) |
CCL4 (17q12) / MCL1 (1q21.3) | MCL1 (1q21.3) / APLNR (11q12.1) | MCL1 (1q21.3) / AR (Xq12) | |
MCL1 (1q21.3) / CTSS (1q21.3) | MCL1 (1q21.3) / GARS (7p14.3) | MCL1 (1q21.3) / MCL1 (1q21.3) | |
MCL1 (1q21.3) / SERPINA1 (14q32.13) | PPP1R12B (1q32.1) / MCL1 (1q21.3) | SLC25A1 (22q11.21) / MCL1 (1q21.3) | |
ZZZ3 (1p31.1) / MCL1 (1q21.3) | MCL1 1q21.3 / AR Xq12 | MCL1 1q21.3 / CTSS 1q21.3 | |
Note | Non-annotated gene. Preliminary data : if you are an author |
DNA/RNA |
Other Leukemias implicated (Data extracted from papers in the Atlas) [ 5 ] |
Burkitt's lymphoma (BL)
Multiple Myeloma t(2;18)(p11;q21)IGK/BCL2 and IGK/KDSR t(4;11)(q21;q23) KMT2A/AFF1 t(14;19)(q32;q13) IGH/Various Partners |
Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ] |
MCL1/CTSS (1q21)
t(X;1)(q12;q21) MCL1/AR |
External links |
Genes in title | automatic search in PubMed |
REVIEW articles | automatic search in PubMed |
Last year publications | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Fri Jan 1 18:24:21 CET 2021 |
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