Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MCM10 (minichromosome maintenance 10 replication initiation factor)

Identity

Alias_namesMCM10 minichromosome maintenance deficient 10 (S. cerevisiae)
minichromosome maintenance complex component 10
Alias_symbol (synonym)PRO2249
CNA43
DNA43
Other alias
HGNC (Hugo) MCM10
LocusID (NCBI) 55388
Atlas_Id 43357
Location 10p13  [Link to chromosome band 10p13]
Location_base_pair Starts at 13161554 and ends at 13211104 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PRPF18 (10p13) / MCM10 (10p13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MCM10   18043
Cards
Entrez_Gene (NCBI)MCM10  55388  minichromosome maintenance 10 replication initiation factor
AliasesCNA43; DNA43; PRO2249
GeneCards (Weizmann)MCM10
Ensembl hg19 (Hinxton)ENSG00000065328 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000065328 [Gene_View]  chr10:13161554-13211104 [Contig_View]  MCM10 [Vega]
ICGC DataPortalENSG00000065328
TCGA cBioPortalMCM10
AceView (NCBI)MCM10
Genatlas (Paris)MCM10
WikiGenes55388
SOURCE (Princeton)MCM10
Genetics Home Reference (NIH)MCM10
Genomic and cartography
GoldenPath hg38 (UCSC)MCM10  -     chr10:13161554-13211104 +  10p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MCM10  -     10p13   [Description]    (hg19-Feb_2009)
EnsemblMCM10 - 10p13 [CytoView hg19]  MCM10 - 10p13 [CytoView hg38]
Mapping of homologs : NCBIMCM10 [Mapview hg19]  MCM10 [Mapview hg38]
OMIM609357   
Gene and transcription
Genbank (Entrez)AB042719 AF119869 AK055695 AK292701 AL136840
RefSeq transcript (Entrez)NM_018518 NM_182751
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MCM10
Cluster EST : UnigeneHs.198363 [ NCBI ]
CGAP (NCI)Hs.198363
Alternative Splicing GalleryENSG00000065328
Gene ExpressionMCM10 [ NCBI-GEO ]   MCM10 [ EBI - ARRAY_EXPRESS ]   MCM10 [ SEEK ]   MCM10 [ MEM ]
Gene Expression Viewer (FireBrowse)MCM10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55388
GTEX Portal (Tissue expression)MCM10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L590   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L590  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L590
Splice isoforms : SwissVarQ7L590
PhosPhoSitePlusQ7L590
Domains : Interpro (EBI)Rep_factor_Mcm10_C    Znf_Mcm10/DnaG   
Domain families : Pfam (Sanger)Mcm10 (PF09332)    zf-primase (PF09329)   
Domain families : Pfam (NCBI)pfam09332    pfam09329   
Domain families : Smart (EMBL)Mcm10 (SM01280)  
Conserved Domain (NCBI)MCM10
DMDM Disease mutations55388
Blocks (Seattle)MCM10
SuperfamilyQ7L590
Human Protein AtlasENSG00000065328
Peptide AtlasQ7L590
HPRD11297
IPIIPI00375915   IPI00164354   IPI00844003   IPI00945557   
Protein Interaction databases
DIP (DOE-UCLA)Q7L590
IntAct (EBI)Q7L590
FunCoupENSG00000065328
BioGRIDMCM10
STRING (EMBL)MCM10
ZODIACMCM10
Ontologies - Pathways
QuickGOQ7L590
Ontology : AmiGOG1/S transition of mitotic cell cycle  DNA replication origin binding  single-stranded DNA binding  protein binding  nucleus  nucleoplasm  nucleolus  DNA replication  DNA replication initiation  cellular response to DNA damage stimulus  cell proliferation  enzyme binding  replication fork protection complex  identical protein binding  metal ion binding  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  DNA replication origin binding  single-stranded DNA binding  protein binding  nucleus  nucleoplasm  nucleolus  DNA replication  DNA replication initiation  cellular response to DNA damage stimulus  cell proliferation  enzyme binding  replication fork protection complex  identical protein binding  metal ion binding  
NDEx NetworkMCM10
Atlas of Cancer Signalling NetworkMCM10
Wikipedia pathwaysMCM10
Orthology - Evolution
OrthoDB55388
GeneTree (enSembl)ENSG00000065328
Phylogenetic Trees/Animal Genes : TreeFamMCM10
HOVERGENQ7L590
HOGENOMQ7L590
Homologs : HomoloGeneMCM10
Homology/Alignments : Family Browser (UCSC)MCM10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMCM10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MCM10
dbVarMCM10
ClinVarMCM10
1000_GenomesMCM10 
Exome Variant ServerMCM10
ExAC (Exome Aggregation Consortium)MCM10 (select the gene name)
Genetic variants : HAPMAP55388
Genomic Variants (DGV)MCM10 [DGVbeta]
DECIPHERMCM10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMCM10 
Mutations
ICGC Data PortalMCM10 
TCGA Data PortalMCM10 
Broad Tumor PortalMCM10
OASIS PortalMCM10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMCM10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMCM10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MCM10
DgiDB (Drug Gene Interaction Database)MCM10
DoCM (Curated mutations)MCM10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MCM10 (select a term)
intoGenMCM10
Cancer3DMCM10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609357   
Orphanet
MedgenMCM10
Genetic Testing Registry MCM10
NextProtQ7L590 [Medical]
TSGene55388
GENETestsMCM10
Target ValidationMCM10
Huge Navigator MCM10 [HugePedia]
snp3D : Map Gene to Disease55388
BioCentury BCIQMCM10
ClinGenMCM10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55388
Chemical/Pharm GKB GenePA30689
Clinical trialMCM10
Miscellaneous
canSAR (ICR)MCM10 (select the gene name)
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMCM10
EVEXMCM10
GoPubMedMCM10
iHOPMCM10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:17:31 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.