Identity
HGNC
LOCATION
6q22.31
LOCUSID
ALIAS
C6orf61,MCMDC1,ODG4,dJ329L24.1,dJ329L24.3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 254394
MIM: 610098
HGNC: 21484
Ensembl: ENSG00000111877
Variants:
dbSNP: 254394
ClinVar: 254394
TCGA: ENSG00000111877
COSMIC: MCM9
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38678026 | 2024 | Mechanism of DNA unwinding by MCM8-9 in complex with HROB. | 1 |
| 38678026 | 2024 | Mechanism of DNA unwinding by MCM8-9 in complex with HROB. | 1 |
| 37309874 | 2023 | Activity, substrate preference and structure of the HsMCM8/9 helicase. | 1 |
| 37309874 | 2023 | Activity, substrate preference and structure of the HsMCM8/9 helicase. | 1 |
| 33750944 | 2021 | The etiology of Down syndrome: Maternal MCM9 polymorphisms increase risk of reduced recombination and nondisjunction of chromosome 21 during meiosis I within oocyte. | 2 |
| 34043945 | 2021 | Structural study of the N-terminal domain of human MCM8/9 complex. | 6 |
| 33750944 | 2021 | The etiology of Down syndrome: Maternal MCM9 polymorphisms increase risk of reduced recombination and nondisjunction of chromosome 21 during meiosis I within oocyte. | 2 |
| 34043945 | 2021 | Structural study of the N-terminal domain of human MCM8/9 complex. | 6 |
| 32145932 | 2020 | Novel pathogenic mutations in minichromosome maintenance complex component 9 (MCM9) responsible for premature ovarian insufficiency. | 17 |
| 32528060 | 2020 | MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage. | 22 |
| 32613604 | 2020 | An exome-wide exploration of cases of primary ovarian insufficiency uncovers novel sequence variants and candidate genes. | 7 |
| 32145932 | 2020 | Novel pathogenic mutations in minichromosome maintenance complex component 9 (MCM9) responsible for premature ovarian insufficiency. | 17 |
| 32528060 | 2020 | MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage. | 22 |
| 32613604 | 2020 | An exome-wide exploration of cases of primary ovarian insufficiency uncovers novel sequence variants and candidate genes. | 7 |
| 30406445 | 2019 | Gene variants identified by whole-exome sequencing in 33 French women with premature ovarian insufficiency. | 23 |
Citation
Dessen P
MCM9 (minichromosome maintenance 9 homologous recombination repair factor)
Atlas Genet Cytogenet Oncol Haematol. 2012-09-01
Online version: http://atlasgeneticsoncology.org/gene/52895/mcm9
