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MCMBP (minichromosome maintenance complex binding protein)

Identity

Alias_namesC10orf119
chromosome 10 open reading frame 119
Alias_symbol (synonym)FLJ13081
MCM-BP
Other alias
HGNC (Hugo) MCMBP
LocusID (NCBI) 79892
Atlas_Id 54446
Location 10q26.11  [Link to chromosome band 10q26]
Location_base_pair Starts at 119829404 and ends at 119872883 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLTB (5q35.2) / MCMBP (10q26.11)G3BP1 (5q33.1) / MCMBP (10q26.11)HDAC9 (7p21.1) / MCMBP (10q26.11)
MCMBP (10q26.11) / FER1L5 (2q11.2)MCMBP (10q26.11) / PSMC5 (17q23.3)MCMBP (10q26.11) / ZNF23 (16q22.2)
TIAL1 (10q26.11) / MCMBP (10q26.11)MCMBP 10q26.11 / ZNF23 16q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  TIAL1/MCMBP (10q26)
t(10;16)(q26;q22) MCMBP/ZNF23


External links

Nomenclature
HGNC (Hugo)MCMBP   25782
Cards
Entrez_Gene (NCBI)MCMBP  79892  minichromosome maintenance complex binding protein
AliasesC10orf119; MCM-BP
GeneCards (Weizmann)MCMBP
Ensembl hg19 (Hinxton)ENSG00000197771 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197771 [Gene_View]  ENSG00000197771 [Sequence]  chr10:119829404-119872883 [Contig_View]  MCMBP [Vega]
ICGC DataPortalENSG00000197771
TCGA cBioPortalMCMBP
AceView (NCBI)MCMBP
Genatlas (Paris)MCMBP
WikiGenes79892
SOURCE (Princeton)MCMBP
Genetics Home Reference (NIH)MCMBP
Genomic and cartography
GoldenPath hg38 (UCSC)MCMBP  -     chr10:119829404-119872883 -  10q26.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MCMBP  -     10q26.11   [Description]    (hg19-Feb_2009)
EnsemblMCMBP - 10q26.11 [CytoView hg19]  MCMBP - 10q26.11 [CytoView hg38]
Mapping of homologs : NCBIMCMBP [Mapview hg19]  MCMBP [Mapview hg38]
OMIM610909   
Gene and transcription
Genbank (Entrez)AA292620 AK001928 AK023143 AK094075 BC000935
RefSeq transcript (Entrez)NM_001256378 NM_001256379 NM_024834
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MCMBP
Cluster EST : UnigeneHs.124246 [ NCBI ]
CGAP (NCI)Hs.124246
Alternative Splicing GalleryENSG00000197771
Gene ExpressionMCMBP [ NCBI-GEO ]   MCMBP [ EBI - ARRAY_EXPRESS ]   MCMBP [ SEEK ]   MCMBP [ MEM ]
Gene Expression Viewer (FireBrowse)MCMBP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79892
GTEX Portal (Tissue expression)MCMBP
Human Protein AtlasENSG00000197771-MCMBP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BTE3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BTE3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BTE3
Splice isoforms : SwissVarQ9BTE3
PhosPhoSitePlusQ9BTE3
Domains : Interpro (EBI)MCM_complex-bd   
Domain families : Pfam (Sanger)MCM_bind (PF09739)   
Domain families : Pfam (NCBI)pfam09739   
Conserved Domain (NCBI)MCMBP
DMDM Disease mutations79892
Blocks (Seattle)MCMBP
PDB (SRS)4KG9   
PDB (PDBSum)4KG9   
PDB (IMB)4KG9   
PDB (RSDB)4KG9   
Structural Biology KnowledgeBase4KG9   
SCOP (Structural Classification of Proteins)4KG9   
CATH (Classification of proteins structures)4KG9   
SuperfamilyQ9BTE3
Human Protein Atlas [tissue]ENSG00000197771-MCMBP [tissue]
Peptide AtlasQ9BTE3
HPRD07624
IPIIPI00478758   IPI00552546   IPI00979721   
Protein Interaction databases
DIP (DOE-UCLA)Q9BTE3
IntAct (EBI)Q9BTE3
FunCoupENSG00000197771
BioGRIDMCMBP
STRING (EMBL)MCMBP
ZODIACMCMBP
Ontologies - Pathways
QuickGOQ9BTE3
Ontology : AmiGOnuclear chromatin  chromatin binding  chromatin binding  protein binding  nucleus  nucleoplasm  cytosol  plasma membrane  DNA-dependent DNA replication  DNA-dependent DNA replication  sister chromatid cohesion  sister chromatid cohesion  MCM complex  MCM complex  cell division  
Ontology : EGO-EBInuclear chromatin  chromatin binding  chromatin binding  protein binding  nucleus  nucleoplasm  cytosol  plasma membrane  DNA-dependent DNA replication  DNA-dependent DNA replication  sister chromatid cohesion  sister chromatid cohesion  MCM complex  MCM complex  cell division  
NDEx NetworkMCMBP
Atlas of Cancer Signalling NetworkMCMBP
Wikipedia pathwaysMCMBP
Orthology - Evolution
OrthoDB79892
GeneTree (enSembl)ENSG00000197771
Phylogenetic Trees/Animal Genes : TreeFamMCMBP
HOVERGENQ9BTE3
HOGENOMQ9BTE3
Homologs : HomoloGeneMCMBP
Homology/Alignments : Family Browser (UCSC)MCMBP
Gene fusions - Rearrangements
Fusion : MitelmanMCMBP/ZNF23 [10q26.11/16q22.2]  
Fusion : MitelmanTIAL1/MCMBP [10q26.11/10q26.11]  [t(10;10)(q26;q26)]  
Fusion PortalMCMBP 10q26.11 ZNF23 16q22.2 BRCA
Fusion Cancer (Beijing)MCMBP [10q26.11]  -  FER1L5 [2q11.2]  [FUSC004266]  [FUSC004266]
Fusion Cancer (Beijing)MCMBP [10q26.11]  -  PSMC5 [17q23.3]  [FUSC004304]
Fusion : QuiverMCMBP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMCMBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MCMBP
dbVarMCMBP
ClinVarMCMBP
1000_GenomesMCMBP 
Exome Variant ServerMCMBP
ExAC (Exome Aggregation Consortium)ENSG00000197771
GNOMAD BrowserENSG00000197771
Varsome BrowserMCMBP
Genetic variants : HAPMAP79892
Genomic Variants (DGV)MCMBP [DGVbeta]
DECIPHERMCMBP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMCMBP 
Mutations
ICGC Data PortalMCMBP 
TCGA Data PortalMCMBP 
Broad Tumor PortalMCMBP
OASIS PortalMCMBP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMCMBP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMCMBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MCMBP
DgiDB (Drug Gene Interaction Database)MCMBP
DoCM (Curated mutations)MCMBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MCMBP (select a term)
intoGenMCMBP
Cancer3DMCMBP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610909   
Orphanet
DisGeNETMCMBP
MedgenMCMBP
Genetic Testing Registry MCMBP
NextProtQ9BTE3 [Medical]
TSGene79892
GENETestsMCMBP
Target ValidationMCMBP
Huge Navigator MCMBP [HugePedia]
snp3D : Map Gene to Disease79892
BioCentury BCIQMCMBP
ClinGenMCMBP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79892
Chemical/Pharm GKB GenePA134862625
Clinical trialMCMBP
Miscellaneous
canSAR (ICR)MCMBP (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMCMBP
EVEXMCMBP
GoPubMedMCMBP
iHOPMCMBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:19:21 CET 2018

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