Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MCUB (mitochondrial calcium uniporter dominant negative beta subunit)

Identity

Alias_namesCCDC109B
coiled-coil domain containing 109B
Alias_symbol (synonym)FLJ20647
Other alias
HGNC (Hugo) MCUB
LocusID (NCBI) 55013
Atlas_Id 78557
Location 4q25  [Link to chromosome band 4q25]
Location_base_pair Starts at 109560199 and ends at 109687716 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MCUB   26076
Cards
Entrez_Gene (NCBI)MCUB  55013  mitochondrial calcium uniporter dominant negative beta subunit
AliasesCCDC109B
GeneCards (Weizmann)MCUB
Ensembl hg19 (Hinxton)ENSG00000005059 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000005059 [Gene_View]  chr4:109560199-109687716 [Contig_View]  MCUB [Vega]
ICGC DataPortalENSG00000005059
TCGA cBioPortalMCUB
AceView (NCBI)MCUB
Genatlas (Paris)MCUB
WikiGenes55013
SOURCE (Princeton)MCUB
Genetics Home Reference (NIH)MCUB
Genomic and cartography
GoldenPath hg38 (UCSC)MCUB  -     chr4:109560199-109687716 +  4q25   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MCUB  -     4q25   [Description]    (hg19-Feb_2009)
EnsemblMCUB - 4q25 [CytoView hg19]  MCUB - 4q25 [CytoView hg38]
Mapping of homologs : NCBIMCUB [Mapview hg19]  MCUB [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK000654 AK095936 AK291098 AK311030 AL832311
RefSeq transcript (Entrez)NM_017918
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MCUB
Cluster EST : UnigeneHs.234149 [ NCBI ]
CGAP (NCI)Hs.234149
Alternative Splicing GalleryENSG00000005059
Gene ExpressionMCUB [ NCBI-GEO ]   MCUB [ EBI - ARRAY_EXPRESS ]   MCUB [ SEEK ]   MCUB [ MEM ]
Gene Expression Viewer (FireBrowse)MCUB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55013
GTEX Portal (Tissue expression)MCUB
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWR8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWR8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWR8
Splice isoforms : SwissVarQ9NWR8
PhosPhoSitePlusQ9NWR8
Domains : Interpro (EBI)Coiled-coil-dom_prot_109_C   
Domain families : Pfam (Sanger)MCU (PF04678)   
Domain families : Pfam (NCBI)pfam04678   
Conserved Domain (NCBI)MCUB
DMDM Disease mutations55013
Blocks (Seattle)MCUB
SuperfamilyQ9NWR8
Human Protein AtlasENSG00000005059
Peptide AtlasQ9NWR8
HPRD07939
IPIIPI00178611   IPI00965797   
Protein Interaction databases
DIP (DOE-UCLA)Q9NWR8
IntAct (EBI)Q9NWR8
FunCoupENSG00000005059
BioGRIDMCUB
STRING (EMBL)MCUB
ZODIACMCUB
Ontologies - Pathways
QuickGOQ9NWR8
Ontology : AmiGOion channel activity  calcium channel activity  mitochondrion  mitochondrial calcium ion transmembrane transport  uniporter activity  calcium channel inhibitor activity  calcium channel inhibitor activity  intrinsic component of membrane  integral component of mitochondrial inner membrane  calcium channel complex  mitochondrial calcium uptake  mitochondrial calcium ion homeostasis  mitochondrial calcium ion homeostasis  regulation of molecular function  uniplex complex  
Ontology : EGO-EBIion channel activity  calcium channel activity  mitochondrion  mitochondrial calcium ion transmembrane transport  uniporter activity  calcium channel inhibitor activity  calcium channel inhibitor activity  intrinsic component of membrane  integral component of mitochondrial inner membrane  calcium channel complex  mitochondrial calcium uptake  mitochondrial calcium ion homeostasis  mitochondrial calcium ion homeostasis  regulation of molecular function  uniplex complex  
NDEx NetworkMCUB
Atlas of Cancer Signalling NetworkMCUB
Wikipedia pathwaysMCUB
Orthology - Evolution
OrthoDB55013
GeneTree (enSembl)ENSG00000005059
Phylogenetic Trees/Animal Genes : TreeFamMCUB
HOVERGENQ9NWR8
HOGENOMQ9NWR8
Homologs : HomoloGeneMCUB
Homology/Alignments : Family Browser (UCSC)MCUB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMCUB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MCUB
dbVarMCUB
ClinVarMCUB
1000_GenomesMCUB 
Exome Variant ServerMCUB
ExAC (Exome Aggregation Consortium)MCUB (select the gene name)
Genetic variants : HAPMAP55013
Genomic Variants (DGV)MCUB [DGVbeta]
DECIPHERMCUB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMCUB 
Mutations
ICGC Data PortalMCUB 
TCGA Data PortalMCUB 
Broad Tumor PortalMCUB
OASIS PortalMCUB [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMCUB
BioMutasearch MCUB
DgiDB (Drug Gene Interaction Database)MCUB
DoCM (Curated mutations)MCUB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MCUB (select a term)
intoGenMCUB
Cancer3DMCUB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenMCUB
Genetic Testing Registry MCUB
NextProtQ9NWR8 [Medical]
TSGene55013
GENETestsMCUB
Huge Navigator MCUB [HugePedia]
snp3D : Map Gene to Disease55013
BioCentury BCIQMCUB
ClinGenMCUB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55013
Chemical/Pharm GKB GenePA145008731
Clinical trialMCUB
Miscellaneous
canSAR (ICR)MCUB (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMCUB
EVEXMCUB
GoPubMedMCUB
iHOPMCUB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 11:38:01 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.