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MCUR1 (mitochondrial calcium uniporter regulator 1)

Identity

Alias_namesC6orf79
CCDC90A
chromosome 6 open reading frame 79
coiled-coil domain containing 90A
Alias_symbol (synonym)FLJ20958
Other aliasFMP32
HGNC (Hugo) MCUR1
LocusID (NCBI) 63933
Atlas_Id 68858
Location 6p23  [Link to chromosome band 6p23]
Location_base_pair Starts at 13786549 and ends at 13814560 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ENO1 (1p36.23) / MCUR1 (6p23)LOC100507412 (-) / MCUR1 (6p23)MCUR1 (6p23) / MCUR1 (6p23)
MCUR1 (6p23) / NEDD1 (12q23.1)MCUR1 (6p23) / S100A10 (1q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;6)(q21;p23) MCUR1/S100A10


External links

Nomenclature
HGNC (Hugo)MCUR1   21097
Cards
Entrez_Gene (NCBI)MCUR1  63933  mitochondrial calcium uniporter regulator 1
AliasesC6orf79; CCDC90A; FMP32
GeneCards (Weizmann)MCUR1
Ensembl hg19 (Hinxton)ENSG00000050393 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000050393 [Gene_View]  ENSG00000050393 [Sequence]  chr6:13786549-13814560 [Contig_View]  MCUR1 [Vega]
ICGC DataPortalENSG00000050393
TCGA cBioPortalMCUR1
AceView (NCBI)MCUR1
Genatlas (Paris)MCUR1
WikiGenes63933
SOURCE (Princeton)MCUR1
Genetics Home Reference (NIH)MCUR1
Genomic and cartography
GoldenPath hg38 (UCSC)MCUR1  -     chr6:13786549-13814560 -  6p23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MCUR1  -     6p23   [Description]    (hg19-Feb_2009)
EnsemblMCUR1 - 6p23 [CytoView hg19]  MCUR1 - 6p23 [CytoView hg38]
Mapping of homologs : NCBIMCUR1 [Mapview hg19]  MCUR1 [Mapview hg38]
OMIM616952   
Gene and transcription
Genbank (Entrez)AI309194 AK024611 AK123750 BC008234 BC016850
RefSeq transcript (Entrez)NM_001031713 NM_022102
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MCUR1
Cluster EST : UnigeneHs.214043 [ NCBI ]
CGAP (NCI)Hs.214043
Alternative Splicing GalleryENSG00000050393
Gene ExpressionMCUR1 [ NCBI-GEO ]   MCUR1 [ EBI - ARRAY_EXPRESS ]   MCUR1 [ SEEK ]   MCUR1 [ MEM ]
Gene Expression Viewer (FireBrowse)MCUR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63933
GTEX Portal (Tissue expression)MCUR1
Human Protein AtlasENSG00000050393-MCUR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AQ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96AQ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96AQ8
Splice isoforms : SwissVarQ96AQ8
PhosPhoSitePlusQ96AQ8
Domains : Interpro (EBI)DUF1640    MCUR1   
Domain families : Pfam (Sanger)DUF1640 (PF07798)   
Domain families : Pfam (NCBI)pfam07798   
Conserved Domain (NCBI)MCUR1
DMDM Disease mutations63933
Blocks (Seattle)MCUR1
SuperfamilyQ96AQ8
Human Protein Atlas [tissue]ENSG00000050393-MCUR1 [tissue]
Peptide AtlasQ96AQ8
HPRD12833
IPIIPI00152975   IPI00844482   
Protein Interaction databases
DIP (DOE-UCLA)Q96AQ8
IntAct (EBI)Q96AQ8
FunCoupENSG00000050393
BioGRIDMCUR1
STRING (EMBL)MCUR1
ZODIACMCUR1
Ontologies - Pathways
QuickGOQ96AQ8
Ontology : AmiGOprotein binding  mitochondrial calcium ion transmembrane transport  integral component of mitochondrial inner membrane  mitochondrial calcium uptake  positive regulation of mitochondrial calcium ion concentration  calcium ion import  
Ontology : EGO-EBIprotein binding  mitochondrial calcium ion transmembrane transport  integral component of mitochondrial inner membrane  mitochondrial calcium uptake  positive regulation of mitochondrial calcium ion concentration  calcium ion import  
NDEx NetworkMCUR1
Atlas of Cancer Signalling NetworkMCUR1
Wikipedia pathwaysMCUR1
Orthology - Evolution
OrthoDB63933
GeneTree (enSembl)ENSG00000050393
Phylogenetic Trees/Animal Genes : TreeFamMCUR1
HOVERGENQ96AQ8
HOGENOMQ96AQ8
Homologs : HomoloGeneMCUR1
Homology/Alignments : Family Browser (UCSC)MCUR1
Gene fusions - Rearrangements
Fusion : QuiverMCUR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMCUR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MCUR1
dbVarMCUR1
ClinVarMCUR1
1000_GenomesMCUR1 
Exome Variant ServerMCUR1
ExAC (Exome Aggregation Consortium)ENSG00000050393
GNOMAD BrowserENSG00000050393
Varsome BrowserMCUR1
Genetic variants : HAPMAP63933
Genomic Variants (DGV)MCUR1 [DGVbeta]
DECIPHERMCUR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMCUR1 
Mutations
ICGC Data PortalMCUR1 
TCGA Data PortalMCUR1 
Broad Tumor PortalMCUR1
OASIS PortalMCUR1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMCUR1
BioMutasearch MCUR1
DgiDB (Drug Gene Interaction Database)MCUR1
DoCM (Curated mutations)MCUR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MCUR1 (select a term)
intoGenMCUR1
Cancer3DMCUR1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616952   
Orphanet
DisGeNETMCUR1
MedgenMCUR1
Genetic Testing Registry MCUR1
NextProtQ96AQ8 [Medical]
TSGene63933
GENETestsMCUR1
Target ValidationMCUR1
Huge Navigator MCUR1 [HugePedia]
snp3D : Map Gene to Disease63933
BioCentury BCIQMCUR1
ClinGenMCUR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD63933
Chemical/Pharm GKB GenePA162381944
Clinical trialMCUR1
Miscellaneous
canSAR (ICR)MCUR1 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMCUR1
EVEXMCUR1
GoPubMedMCUR1
iHOPMCUR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Jul 30 14:12:30 CEST 2018

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