MDFI (MyoD family inhibitor)

2012-02-01  

Identity

HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
I-MF,I-mfa
FUSION GENES

Other Information

Locus ID:

NCBI: 4188
MIM: 604971
HGNC: 6967
Ensembl: ENSG00000112559

Variants:

dbSNP: 4188
ClinVar: 4188
TCGA: ENSG00000112559
COSMIC: MDFI

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112559ENST00000230321Q99750
ENSG00000112559ENST00000230321A0A024RCY2
ENSG00000112559ENST00000373050B1AKB6
ENSG00000112559ENST00000373051Q99750
ENSG00000112559ENST00000373051A0A024RCY2
ENSG00000112559ENST00000419164B1AKB7
ENSG00000112559ENST00000432027B1AKB8
ENSG00000112559ENST00000435476B1AKB9
ENSG00000112559ENST00000441667B1AKC1
ENSG00000112559ENST00000446650B1AKC0

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383758212024MDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathway.1
383758212024MDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathway.1
338999502021Multifaceted array-based keloidal gene expression profiling reveals specific MDFI upregulation in keloid lesions.1
338999502021Multifaceted array-based keloidal gene expression profiling reveals specific MDFI upregulation in keloid lesions.1
324574532020Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer.17
324574532020Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer.17
287825762017DNA methylation of CMTM3, SSTR2, and MDFI genes in colorectal cancer.29
287825762017DNA methylation of CMTM3, SSTR2, and MDFI genes in colorectal cancer.29
216644112011I-mfa domain proteins specifically interact with SERTA domain proteins and repress their transactivating functions.10
216644112011I-mfa domain proteins specifically interact with SERTA domain proteins and repress their transactivating functions.10
152077262004Myogenic repressor I-mfa interferes with the function of Zic family proteins.17
152077262004Myogenic repressor I-mfa interferes with the function of Zic family proteins.17
145302672003Inhibitor of myogenic family, a novel suppressor of store-operated currents through an interaction with TRPC1.22
145302672003Inhibitor of myogenic family, a novel suppressor of store-operated currents through an interaction with TRPC1.22

Citation

Dessen P

MDFI (MyoD family inhibitor)

Atlas Genet Cytogenet Oncol Haematol. 2012-02-01

Online version: http://atlasgeneticsoncology.org/gene/52596/mdfi