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MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2)

Identity

Other aliasMAMDC1
c14_5286
HGNC (Hugo) MDGA2
LocusID (NCBI) 161357
Atlas_Id 57033
Location 14q21.3  [Link to chromosome band 14q21]
Location_base_pair Starts at 46839625 and ends at 47674954 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ASAP1 (8q24.21) / MDGA2 (14q21.3)BCAT1 (12p12.1) / MDGA2 (14q21.3)MDGA2 (14q21.3) / CSTA (3q21.1)
MDGA2 (14q21.3) / LOC100499227 ()TMEM59 (1p32.3) / MDGA2 (14q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MDGA2   19835
Cards
Entrez_Gene (NCBI)MDGA2  161357  MAM domain containing glycosylphosphatidylinositol anchor 2
AliasesMAMDC1; c14_5286
GeneCards (Weizmann)MDGA2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr14:46839625-47674954 [Contig_View]  MDGA2 [Vega]
TCGA cBioPortalMDGA2
AceView (NCBI)MDGA2
Genatlas (Paris)MDGA2
WikiGenes161357
SOURCE (Princeton)MDGA2
Genetics Home Reference (NIH)MDGA2
Genomic and cartography
GoldenPath hg38 (UCSC)MDGA2  -     chr14:46839625-47674954 -  14q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MDGA2  -     14q21.3   [Description]    (hg19-Feb_2009)
EnsemblMDGA2 - 14q21.3 [CytoView hg19]  MDGA2 - 14q21.3 [CytoView hg38]
Mapping of homologs : NCBIMDGA2 [Mapview hg19]  MDGA2 [Mapview hg38]
OMIM611128   
Gene and transcription
Genbank (Entrez)AK123307 AK309211 AY328482 AY358125 AY369208
RefSeq transcript (Entrez)NM_001113498 NM_182830
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MDGA2
Cluster EST : UnigeneHs.436380 [ NCBI ]
CGAP (NCI)Hs.436380
Gene ExpressionMDGA2 [ NCBI-GEO ]   MDGA2 [ EBI - ARRAY_EXPRESS ]   MDGA2 [ SEEK ]   MDGA2 [ MEM ]
Gene Expression Viewer (FireBrowse)MDGA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)161357
GTEX Portal (Tissue expression)MDGA2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z553   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z553  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z553
Splice isoforms : SwissVarQ7Z553
PhosPhoSitePlusQ7Z553
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    IG_LIKE (PS50835)    MAM_2 (PS50060)   
Domains : Interpro (EBI)ConA-like_dom    FN3_dom    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    MAM_dom   
Domain families : Pfam (Sanger)I-set (PF07679)    MAM (PF00629)   
Domain families : Pfam (NCBI)pfam07679    pfam00629   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  MAM (SM00137)  
Conserved Domain (NCBI)MDGA2
DMDM Disease mutations161357
Blocks (Seattle)MDGA2
SuperfamilyQ7Z553
Peptide AtlasQ7Z553
IPIIPI00936317   IPI00976664   IPI01025208   IPI01025445   IPI01025587   IPI00337351   IPI00793296   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z553
IntAct (EBI)Q7Z553
BioGRIDMDGA2
STRING (EMBL)MDGA2
ZODIACMDGA2
Ontologies - Pathways
QuickGOQ7Z553
Ontology : AmiGOextracellular region  plasma membrane  C-terminal protein lipidation  spinal cord motor neuron differentiation  anchored component of membrane  
Ontology : EGO-EBIextracellular region  plasma membrane  C-terminal protein lipidation  spinal cord motor neuron differentiation  anchored component of membrane  
NDEx NetworkMDGA2
Atlas of Cancer Signalling NetworkMDGA2
Wikipedia pathwaysMDGA2
Orthology - Evolution
OrthoDB161357
Phylogenetic Trees/Animal Genes : TreeFamMDGA2
HOVERGENQ7Z553
HOGENOMQ7Z553
Homologs : HomoloGeneMDGA2
Homology/Alignments : Family Browser (UCSC)MDGA2
Gene fusions - Rearrangements
Tumor Fusion PortalMDGA2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMDGA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MDGA2
dbVarMDGA2
ClinVarMDGA2
1000_GenomesMDGA2 
Exome Variant ServerMDGA2
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP161357
Genomic Variants (DGV)MDGA2 [DGVbeta]
DECIPHERMDGA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMDGA2 
Mutations
ICGC Data PortalMDGA2 
TCGA Data PortalMDGA2 
Broad Tumor PortalMDGA2
OASIS PortalMDGA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMDGA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMDGA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MDGA2
DgiDB (Drug Gene Interaction Database)MDGA2
DoCM (Curated mutations)MDGA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MDGA2 (select a term)
intoGenMDGA2
Cancer3DMDGA2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611128   
Orphanet
DisGeNETMDGA2
MedgenMDGA2
Genetic Testing Registry MDGA2
NextProtQ7Z553 [Medical]
TSGene161357
GENETestsMDGA2
Target ValidationMDGA2
Huge Navigator MDGA2 [HugePedia]
snp3D : Map Gene to Disease161357
BioCentury BCIQMDGA2
ClinGenMDGA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD161357
Chemical/Pharm GKB GenePA162395090
Clinical trialMDGA2
Miscellaneous
canSAR (ICR)MDGA2 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMDGA2
EVEXMDGA2
GoPubMedMDGA2
iHOPMDGA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:22:00 CET 2017

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