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MDH1B (malate dehydrogenase 1B)

Identity

Alias_namesmalate dehydrogenase 1B, NAD (soluble)
Alias_symbol (synonym)FLJ25341
RP11-95H11
Other alias
HGNC (Hugo) MDH1B
LocusID (NCBI) 130752
Atlas_Id 68861
Location 2q33.3  [Link to chromosome band 2q33]
Location_base_pair Starts at 206737765 and ends at 206765549 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MDH1B   17836
Cards
Entrez_Gene (NCBI)MDH1B  130752  malate dehydrogenase 1B
AliasesRP11-95H11
GeneCards (Weizmann)MDH1B
Ensembl hg19 (Hinxton)ENSG00000138400 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138400 [Gene_View]  chr2:206737765-206765549 [Contig_View]  MDH1B [Vega]
ICGC DataPortalENSG00000138400
TCGA cBioPortalMDH1B
AceView (NCBI)MDH1B
Genatlas (Paris)MDH1B
WikiGenes130752
SOURCE (Princeton)MDH1B
Genetics Home Reference (NIH)MDH1B
Genomic and cartography
GoldenPath hg38 (UCSC)MDH1B  -     chr2:206737765-206765549 -  2q33.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MDH1B  -     2q33.3   [Description]    (hg19-Feb_2009)
EnsemblMDH1B - 2q33.3 [CytoView hg19]  MDH1B - 2q33.3 [CytoView hg38]
Mapping of homologs : NCBIMDH1B [Mapview hg19]  MDH1B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI076012 AK058070 AK292378 AK292386 AK302250
RefSeq transcript (Entrez)NM_001039845 NM_001282940 NM_001330223 NM_001330224 NM_001330225 NM_001330226 NM_206892
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MDH1B
Cluster EST : UnigeneHs.147816 [ NCBI ]
CGAP (NCI)Hs.147816
Alternative Splicing GalleryENSG00000138400
Gene ExpressionMDH1B [ NCBI-GEO ]   MDH1B [ EBI - ARRAY_EXPRESS ]   MDH1B [ SEEK ]   MDH1B [ MEM ]
Gene Expression Viewer (FireBrowse)MDH1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)130752
GTEX Portal (Tissue expression)MDH1B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5I0G3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5I0G3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5I0G3
Splice isoforms : SwissVarQ5I0G3
PhosPhoSitePlusQ5I0G3
Domains : Interpro (EBI)Lactate_DH/Glyco_Ohase_4_C    Malate_DH_type2    NAD(P)-bd_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)MDH1B
DMDM Disease mutations130752
Blocks (Seattle)MDH1B
SuperfamilyQ5I0G3
Human Protein AtlasENSG00000138400
Peptide AtlasQ5I0G3
HPRD14375
IPIIPI00292741   IPI00890813   IPI00743131   IPI00926595   IPI00927796   
Protein Interaction databases
DIP (DOE-UCLA)Q5I0G3
IntAct (EBI)Q5I0G3
FunCoupENSG00000138400
BioGRIDMDH1B
STRING (EMBL)MDH1B
ZODIACMDH1B
Ontologies - Pathways
QuickGOQ5I0G3
Ontology : AmiGOcytoplasm  carbohydrate metabolic process  tricarboxylic acid cycle  oxaloacetate metabolic process  malate metabolic process  NADH metabolic process  L-malate dehydrogenase activity  
Ontology : EGO-EBIcytoplasm  carbohydrate metabolic process  tricarboxylic acid cycle  oxaloacetate metabolic process  malate metabolic process  NADH metabolic process  L-malate dehydrogenase activity  
NDEx NetworkMDH1B
Atlas of Cancer Signalling NetworkMDH1B
Wikipedia pathwaysMDH1B
Orthology - Evolution
OrthoDB130752
GeneTree (enSembl)ENSG00000138400
Phylogenetic Trees/Animal Genes : TreeFamMDH1B
HOVERGENQ5I0G3
HOGENOMQ5I0G3
Homologs : HomoloGeneMDH1B
Homology/Alignments : Family Browser (UCSC)MDH1B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMDH1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MDH1B
dbVarMDH1B
ClinVarMDH1B
1000_GenomesMDH1B 
Exome Variant ServerMDH1B
ExAC (Exome Aggregation Consortium)MDH1B (select the gene name)
Genetic variants : HAPMAP130752
Genomic Variants (DGV)MDH1B [DGVbeta]
DECIPHERMDH1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMDH1B 
Mutations
ICGC Data PortalMDH1B 
TCGA Data PortalMDH1B 
Broad Tumor PortalMDH1B
OASIS PortalMDH1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMDH1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMDH1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MDH1B
DgiDB (Drug Gene Interaction Database)MDH1B
DoCM (Curated mutations)MDH1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MDH1B (select a term)
intoGenMDH1B
Cancer3DMDH1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenMDH1B
Genetic Testing Registry MDH1B
NextProtQ5I0G3 [Medical]
TSGene130752
GENETestsMDH1B
Target ValidationMDH1B
Huge Navigator MDH1B [HugePedia]
snp3D : Map Gene to Disease130752
BioCentury BCIQMDH1B
ClinGenMDH1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD130752
Chemical/Pharm GKB GenePA30715
Clinical trialMDH1B
Miscellaneous
canSAR (ICR)MDH1B (select the gene name)
Probes
Litterature
PubMed2 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMDH1B
EVEXMDH1B
GoPubMedMDH1B
iHOPMDH1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:27:05 CEST 2017

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