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MDM1 (Mdm1 nuclear protein)

Identity

Alias_namesMdm4, transformed 3T3 cell double minute 1, p53 binding protein (mouse)
Mdm1 nuclear protein homolog (mouse)
Other alias-
HGNC (Hugo) MDM1
LocusID (NCBI) 56890
Atlas_Id 68863
Location 12q15  [Link to chromosome band 12q15]
Location_base_pair Starts at 68294566 and ends at 68332381 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CPSF6 (12q15) / MDM1 (12q15)RAB21 (12q21.1) / MDM1 (12q15)RAB21 MDM1
CPSF6 MDM1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MDM1   29917
Cards
Entrez_Gene (NCBI)MDM1  56890  Mdm1 nuclear protein
Aliases
GeneCards (Weizmann)MDM1
Ensembl hg19 (Hinxton)ENSG00000111554 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111554 [Gene_View]  chr12:68294566-68332381 [Contig_View]  MDM1 [Vega]
ICGC DataPortalENSG00000111554
TCGA cBioPortalMDM1
AceView (NCBI)MDM1
Genatlas (Paris)MDM1
WikiGenes56890
SOURCE (Princeton)MDM1
Genetics Home Reference (NIH)MDM1
Genomic and cartography
GoldenPath hg38 (UCSC)MDM1  -     chr12:68294566-68332381 -  12q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MDM1  -     12q15   [Description]    (hg19-Feb_2009)
EnsemblMDM1 - 12q15 [CytoView hg19]  MDM1 - 12q15 [CytoView hg38]
Mapping of homologs : NCBIMDM1 [Mapview hg19]  MDM1 [Mapview hg38]
OMIM613813   
Gene and transcription
Genbank (Entrez)AF007130 AF267851 AK026745 AK297311 AK314461
RefSeq transcript (Entrez)NM_001205028 NM_001205029 NM_017440 NM_020128
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MDM1
Cluster EST : UnigeneHs.655702 [ NCBI ]
CGAP (NCI)Hs.655702
Alternative Splicing GalleryENSG00000111554
Gene ExpressionMDM1 [ NCBI-GEO ]   MDM1 [ EBI - ARRAY_EXPRESS ]   MDM1 [ SEEK ]   MDM1 [ MEM ]
Gene Expression Viewer (FireBrowse)MDM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56890
GTEX Portal (Tissue expression)MDM1
Human Protein AtlasENSG00000111554-MDM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TC05   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TC05  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TC05
Splice isoforms : SwissVarQ8TC05
PhosPhoSitePlusQ8TC05
Domains : Interpro (EBI)MDM1   
Domain families : Pfam (Sanger)MDM1 (PF15501)   
Domain families : Pfam (NCBI)pfam15501   
Conserved Domain (NCBI)MDM1
DMDM Disease mutations56890
Blocks (Seattle)MDM1
SuperfamilyQ8TC05
Human Protein Atlas [tissue]ENSG00000111554-MDM1 [tissue]
Peptide AtlasQ8TC05
HPRD14376
IPIIPI00303260   IPI00024498   IPI00178639   IPI01013302   IPI01011833   IPI01011170   IPI00790693   IPI01010132   
Protein Interaction databases
DIP (DOE-UCLA)Q8TC05
IntAct (EBI)Q8TC05
FunCoupENSG00000111554
BioGRIDMDM1
STRING (EMBL)MDM1
ZODIACMDM1
Ontologies - Pathways
QuickGOQ8TC05
Ontology : AmiGOnucleus  centrosome  centriole  cytosol  microtubule  microtubule binding  negative regulation of centriole replication  retina development in camera-type eye  
Ontology : EGO-EBInucleus  centrosome  centriole  cytosol  microtubule  microtubule binding  negative regulation of centriole replication  retina development in camera-type eye  
NDEx NetworkMDM1
Atlas of Cancer Signalling NetworkMDM1
Wikipedia pathwaysMDM1
Orthology - Evolution
OrthoDB56890
GeneTree (enSembl)ENSG00000111554
Phylogenetic Trees/Animal Genes : TreeFamMDM1
HOVERGENQ8TC05
HOGENOMQ8TC05
Homologs : HomoloGeneMDM1
Homology/Alignments : Family Browser (UCSC)MDM1
Gene fusions - Rearrangements
Fusion: TCGA_MDACCRAB21 MDM1
Fusion: TCGA_MDACCCPSF6 MDM1
Tumor Fusion PortalMDM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMDM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MDM1
dbVarMDM1
ClinVarMDM1
1000_GenomesMDM1 
Exome Variant ServerMDM1
ExAC (Exome Aggregation Consortium)ENSG00000111554
GNOMAD BrowserENSG00000111554
Genetic variants : HAPMAP56890
Genomic Variants (DGV)MDM1 [DGVbeta]
DECIPHERMDM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMDM1 
Mutations
ICGC Data PortalMDM1 
TCGA Data PortalMDM1 
Broad Tumor PortalMDM1
OASIS PortalMDM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMDM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMDM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MDM1
DgiDB (Drug Gene Interaction Database)MDM1
DoCM (Curated mutations)MDM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MDM1 (select a term)
intoGenMDM1
Cancer3DMDM1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613813   
Orphanet
DisGeNETMDM1
MedgenMDM1
Genetic Testing Registry MDM1
NextProtQ8TC05 [Medical]
TSGene56890
GENETestsMDM1
Target ValidationMDM1
Huge Navigator MDM1 [HugePedia]
snp3D : Map Gene to Disease56890
BioCentury BCIQMDM1
ClinGenMDM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56890
Chemical/Pharm GKB GenePA134879752
Clinical trialMDM1
Miscellaneous
canSAR (ICR)MDM1 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMDM1
EVEXMDM1
GoPubMedMDM1
iHOPMDM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:26:47 CET 2017

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