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MDP1 (magnesium-dependent phosphatase 1)

Identity

Alias_symbol (synonym)MGC5987
FN6Pase
Other aliasFN6PASE
MDP-1
HGNC (Hugo) MDP1
LocusID (NCBI) 145553
Atlas_Id 68865
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 24683143 and ends at 24685276 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MDP1 (14q12) / CHMP4A (14q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MDP1   28781
Cards
Entrez_Gene (NCBI)MDP1  145553  magnesium-dependent phosphatase 1
AliasesFN6PASE; MDP-1
GeneCards (Weizmann)MDP1
Ensembl hg19 (Hinxton)ENSG00000213920 [Gene_View]  chr14:24683143-24685276 [Contig_View]  MDP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000213920 [Gene_View]  chr14:24683143-24685276 [Contig_View]  MDP1 [Vega]
ICGC DataPortalENSG00000213920
TCGA cBioPortalMDP1
AceView (NCBI)MDP1
Genatlas (Paris)MDP1
WikiGenes145553
SOURCE (Princeton)MDP1
Genetics Home Reference (NIH)MDP1
Genomic and cartography
GoldenPath hg19 (UCSC)MDP1  -     chr14:24683143-24685276 -  14q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MDP1  -     14q12   [Description]    (hg38-Dec_2013)
EnsemblMDP1 - 14q12 [CytoView hg19]  MDP1 - 14q12 [CytoView hg38]
Mapping of homologs : NCBIMDP1 [Mapview hg19]  MDP1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA918790 AK092821 AK312038 BC009495 BC046912
RefSeq transcript (Entrez)NM_001199821 NM_001199822 NM_138476
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)MDP1
Cluster EST : UnigeneHs.220963 [ NCBI ]
CGAP (NCI)Hs.220963
Alternative Splicing GalleryENSG00000213920
Gene ExpressionMDP1 [ NCBI-GEO ]   MDP1 [ EBI - ARRAY_EXPRESS ]   MDP1 [ SEEK ]   MDP1 [ MEM ]
Gene Expression Viewer (FireBrowse)MDP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)145553
GTEX Portal (Tissue expression)MDP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86V88   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86V88  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86V88
Splice isoforms : SwissVarQ86V88
Catalytic activity : Enzyme3.1.3.- [ Enzyme-Expasy ]   3.1.3.-3.1.3.- [ IntEnz-EBI ]   3.1.3.- [ BRENDA ]   3.1.3.- [ KEGG ]   
PhosPhoSitePlusQ86V88
Domains : Interpro (EBI)HAD-like_dom    HAD_SF_ppase_IIIC    MDP_1_eu    MDP_1_eu_arc   
Domain families : Pfam (Sanger)Acid_PPase (PF12689)   
Domain families : Pfam (NCBI)pfam12689   
Conserved Domain (NCBI)MDP1
DMDM Disease mutations145553
Blocks (Seattle)MDP1
PDB (SRS)2WM8   
PDB (PDBSum)2WM8   
PDB (IMB)2WM8   
PDB (RSDB)2WM8   
Structural Biology KnowledgeBase2WM8   
SCOP (Structural Classification of Proteins)2WM8   
CATH (Classification of proteins structures)2WM8   
SuperfamilyQ86V88
Human Protein AtlasENSG00000213920
Peptide AtlasQ86V88
HPRD14695
IPIIPI00337556   IPI00385758   IPI00384628   IPI00985332   
Protein Interaction databases
DIP (DOE-UCLA)Q86V88
IntAct (EBI)Q86V88
FunCoupENSG00000213920
BioGRIDMDP1
STRING (EMBL)MDP1
ZODIACMDP1
Ontologies - Pathways
QuickGOQ86V88
Ontology : AmiGOprotein tyrosine phosphatase activity  peptidyl-tyrosine dephosphorylation  metal ion binding  extracellular exosome  
Ontology : EGO-EBIprotein tyrosine phosphatase activity  peptidyl-tyrosine dephosphorylation  metal ion binding  extracellular exosome  
NDEx NetworkMDP1
Atlas of Cancer Signalling NetworkMDP1
Wikipedia pathwaysMDP1
Orthology - Evolution
OrthoDB145553
GeneTree (enSembl)ENSG00000213920
Phylogenetic Trees/Animal Genes : TreeFamMDP1
HOVERGENQ86V88
HOGENOMQ86V88
Homologs : HomoloGeneMDP1
Homology/Alignments : Family Browser (UCSC)MDP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMDP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MDP1
dbVarMDP1
ClinVarMDP1
1000_GenomesMDP1 
Exome Variant ServerMDP1
ExAC (Exome Aggregation Consortium)MDP1 (select the gene name)
Genetic variants : HAPMAP145553
Genomic Variants (DGV)MDP1 [DGVbeta]
DECIPHER (Syndromes)14:24683143-24685276  ENSG00000213920
CONAN: Copy Number AnalysisMDP1 
Mutations
ICGC Data PortalMDP1 
TCGA Data PortalMDP1 
Broad Tumor PortalMDP1
OASIS PortalMDP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMDP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMDP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MDP1
DgiDB (Drug Gene Interaction Database)MDP1
DoCM (Curated mutations)MDP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MDP1 (select a term)
intoGenMDP1
Cancer3DMDP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenMDP1
Genetic Testing Registry MDP1
NextProtQ86V88 [Medical]
TSGene145553
GENETestsMDP1
Huge Navigator MDP1 [HugePedia]
snp3D : Map Gene to Disease145553
BioCentury BCIQMDP1
ClinGenMDP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD145553
Chemical/Pharm GKB GenePA165479165
Clinical trialMDP1
Miscellaneous
canSAR (ICR)MDP1 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMDP1
EVEXMDP1
GoPubMedMDP1
iHOPMDP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 12:27:55 CET 2017

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