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MED11 (mediator complex subunit 11)

Identity

Alias_namesmediator of RNA polymerase II transcription, subunit 11 homolog (S. cerevisiae)
Alias_symbol (synonym)HSPC296
MGC88387
Other alias
HGNC (Hugo) MED11
LocusID (NCBI) 400569
Atlas_Id 68870
Location 17p13.2  [Link to chromosome band 17p13]
Location_base_pair Starts at 4731408 and ends at 4733610 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KDM5A (12p13.33) / MED11 (17p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MED11   32687
Cards
Entrez_Gene (NCBI)MED11  400569  mediator complex subunit 11
AliasesHSPC296
GeneCards (Weizmann)MED11
Ensembl hg19 (Hinxton)ENSG00000161920 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000161920 [Gene_View]  chr17:4731408-4733610 [Contig_View]  MED11 [Vega]
ICGC DataPortalENSG00000161920
TCGA cBioPortalMED11
AceView (NCBI)MED11
Genatlas (Paris)MED11
WikiGenes400569
SOURCE (Princeton)MED11
Genetics Home Reference (NIH)MED11
Genomic and cartography
GoldenPath hg38 (UCSC)MED11  -     chr17:4731408-4733610 +  17p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MED11  -     17p13.2   [Description]    (hg19-Feb_2009)
EnsemblMED11 - 17p13.2 [CytoView hg19]  MED11 - 17p13.2 [CytoView hg38]
Mapping of homologs : NCBIMED11 [Mapview hg19]  MED11 [Mapview hg38]
OMIM612383   
Gene and transcription
Genbank (Entrez)AA806707 AF161414 BC070377 BG503911 HG518163
RefSeq transcript (Entrez)NM_001001683 NM_001305000
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MED11
Cluster EST : UnigeneHs.513885 [ NCBI ]
CGAP (NCI)Hs.513885
Alternative Splicing GalleryENSG00000161920
Gene ExpressionMED11 [ NCBI-GEO ]   MED11 [ EBI - ARRAY_EXPRESS ]   MED11 [ SEEK ]   MED11 [ MEM ]
Gene Expression Viewer (FireBrowse)MED11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)400569
GTEX Portal (Tissue expression)MED11
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P086   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P086  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P086
Splice isoforms : SwissVarQ9P086
PhosPhoSitePlusQ9P086
Domains : Interpro (EBI)Mediator_Med11   
Domain families : Pfam (Sanger)Med11 (PF10280)   
Domain families : Pfam (NCBI)pfam10280   
Conserved Domain (NCBI)MED11
DMDM Disease mutations400569
Blocks (Seattle)MED11
SuperfamilyQ9P086
Human Protein AtlasENSG00000161920
Peptide AtlasQ9P086
HPRD14709
IPIIPI00000305   
Protein Interaction databases
DIP (DOE-UCLA)Q9P086
IntAct (EBI)Q9P086
FunCoupENSG00000161920
BioGRIDMED11
STRING (EMBL)MED11
ZODIACMED11
Ontologies - Pathways
QuickGOQ9P086
Ontology : AmiGOubiquitin ligase complex  RNA polymerase II transcription cofactor activity  protein binding  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  protein ubiquitination  mediator complex  ubiquitin protein ligase activity  
Ontology : EGO-EBIubiquitin ligase complex  RNA polymerase II transcription cofactor activity  protein binding  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  protein ubiquitination  mediator complex  ubiquitin protein ligase activity  
NDEx NetworkMED11
Atlas of Cancer Signalling NetworkMED11
Wikipedia pathwaysMED11
Orthology - Evolution
OrthoDB400569
GeneTree (enSembl)ENSG00000161920
Phylogenetic Trees/Animal Genes : TreeFamMED11
HOVERGENQ9P086
HOGENOMQ9P086
Homologs : HomoloGeneMED11
Homology/Alignments : Family Browser (UCSC)MED11
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMED11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MED11
dbVarMED11
ClinVarMED11
1000_GenomesMED11 
Exome Variant ServerMED11
ExAC (Exome Aggregation Consortium)MED11 (select the gene name)
Genetic variants : HAPMAP400569
Genomic Variants (DGV)MED11 [DGVbeta]
DECIPHERMED11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMED11 
Mutations
ICGC Data PortalMED11 
TCGA Data PortalMED11 
Broad Tumor PortalMED11
OASIS PortalMED11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMED11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMED11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MED11
DgiDB (Drug Gene Interaction Database)MED11
DoCM (Curated mutations)MED11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MED11 (select a term)
intoGenMED11
Cancer3DMED11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612383   
Orphanet
MedgenMED11
Genetic Testing Registry MED11
NextProtQ9P086 [Medical]
TSGene400569
GENETestsMED11
Target ValidationMED11
Huge Navigator MED11 [HugePedia]
snp3D : Map Gene to Disease400569
BioCentury BCIQMED11
ClinGenMED11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD400569
Chemical/Pharm GKB GenePA144596413
Clinical trialMED11
Miscellaneous
canSAR (ICR)MED11 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMED11
EVEXMED11
GoPubMedMED11
iHOPMED11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:25:45 CEST 2017

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