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MED20 (mediator complex subunit 20)

Identity

Alias (NCBI)PRO0213
SRB2
TRFP
HGNC (Hugo) MED20
HGNC Alias symbDKFZp586D2223
PRO0213
HGNC Previous nameTRFP
HGNC Previous nameTrf (TATA binding protein-related factor)-proximal homolog (Drosophila)
LocusID (NCBI) 9477
Atlas_Id 68876
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41905354 and ends at 41921139 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AKR1A1 (1p34.1) / MED20 (6p21.1)MED20 (6p21.1) / RNF182 (6p23)MED20 (6p21.1) / TLL2 (10q24.1)
MED20 (6p21.1) / USP49 (6p21.1)USP49 (6p21.1) / MED20 (6p21.1)MED20 RNF182
MED20 TLL2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MED20   16840
Cards
Entrez_Gene (NCBI)MED20    mediator complex subunit 20
AliasesPRO0213; SRB2; TRFP
GeneCards (Weizmann)MED20
Ensembl hg19 (Hinxton)ENSG00000124641 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124641 [Gene_View]  ENSG00000124641 [Sequence]  chr6:41905354-41921139 [Contig_View]  MED20 [Vega]
ICGC DataPortalENSG00000124641
TCGA cBioPortalMED20
AceView (NCBI)MED20
Genatlas (Paris)MED20
SOURCE (Princeton)MED20
Genetics Home Reference (NIH)MED20
Genomic and cartography
GoldenPath hg38 (UCSC)MED20  -     chr6:41905354-41921139 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MED20  -     6p21.1   [Description]    (hg19-Feb_2009)
GoldenPathMED20 - 6p21.1 [CytoView hg19]  MED20 - 6p21.1 [CytoView hg38]
ImmunoBaseENSG00000124641
Genome Data Viewer NCBIMED20 [Mapview hg19]  
OMIM612915   
Gene and transcription
Genbank (Entrez)AF097725 AF116602 AJ420544 AK023092 AK097385
RefSeq transcript (Entrez)NM_001305455 NM_001305456 NM_001305457 NM_004275
Consensus coding sequences : CCDS (NCBI)MED20
Gene ExpressionMED20 [ NCBI-GEO ]   MED20 [ EBI - ARRAY_EXPRESS ]   MED20 [ SEEK ]   MED20 [ MEM ]
Gene Expression Viewer (FireBrowse)MED20 [ Firebrowse - Broad ]
GenevisibleExpression of MED20 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9477
GTEX Portal (Tissue expression)MED20
Human Protein AtlasENSG00000124641-MED20 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H944   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H944  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H944
PhosPhoSitePlusQ9H944
Domains : Interpro (EBI)Mediator_Med20   
Domain families : Pfam (Sanger)Med20 (PF08612)   
Domain families : Pfam (NCBI)pfam08612   
Conserved Domain (NCBI)MED20
SuperfamilyQ9H944
AlphaFold pdb e-kbQ9H944   
Human Protein Atlas [tissue]ENSG00000124641-MED20 [tissue]
HPRD15638
Protein Interaction databases
DIP (DOE-UCLA)Q9H944
IntAct (EBI)Q9H944
BioGRIDMED20
STRING (EMBL)MED20
ZODIACMED20
Ontologies - Pathways
QuickGOQ9H944
Ontology : AmiGOtranscription coactivator activity  DNA-directed 5'-3' RNA polymerase activity  protein binding  nucleoplasm  transcription, DNA-templated  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  mediator complex  mediator complex  positive regulation of transcription, DNA-templated  regulation of transcription initiation from RNA polymerase II promoter  
Ontology : EGO-EBItranscription coactivator activity  DNA-directed 5'-3' RNA polymerase activity  protein binding  nucleoplasm  transcription, DNA-templated  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  mediator complex  mediator complex  positive regulation of transcription, DNA-templated  regulation of transcription initiation from RNA polymerase II promoter  
NDEx NetworkMED20
Atlas of Cancer Signalling NetworkMED20
Wikipedia pathwaysMED20
Orthology - Evolution
OrthoDB9477
GeneTree (enSembl)ENSG00000124641
Phylogenetic Trees/Animal Genes : TreeFamMED20
Homologs : HomoloGeneMED20
Homology/Alignments : Family Browser (UCSC)MED20
Gene fusions - Rearrangements
Fusion : QuiverMED20
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMED20 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MED20
dbVarMED20
ClinVarMED20
MonarchMED20
1000_GenomesMED20 
Exome Variant ServerMED20
GNOMAD BrowserENSG00000124641
Varsome BrowserMED20
ACMGMED20 variants
VarityQ9H944
Genomic Variants (DGV)MED20 [DGVbeta]
DECIPHERMED20 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMED20 
Mutations
ICGC Data PortalMED20 
TCGA Data PortalMED20 
Broad Tumor PortalMED20
OASIS PortalMED20 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMED20  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMED20
Mutations and Diseases : HGMDMED20
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMED20
DgiDB (Drug Gene Interaction Database)MED20
DoCM (Curated mutations)MED20
CIViC (Clinical Interpretations of Variants in Cancer)MED20
Cancer3DMED20
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612915   
Orphanet
DisGeNETMED20
MedgenMED20
Genetic Testing Registry MED20
NextProtQ9H944 [Medical]
GENETestsMED20
Target ValidationMED20
Huge Navigator MED20 [HugePedia]
ClinGenMED20
Clinical trials, drugs, therapy
MyCancerGenomeMED20
Protein Interactions : CTDMED20
Pharm GKB GenePA162395472
PharosQ9H944
Clinical trialMED20
Miscellaneous
canSAR (ICR)MED20
HarmonizomeMED20
DataMed IndexMED20
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMED20
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:07:04 CEST 2021

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