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MED22 (mediator complex subunit 22)

Identity

Alias_namesSURF5
surfeit 5
Alias_symbol (synonym)Med24
Other aliasMED24
surf-5
HGNC (Hugo) MED22
LocusID (NCBI) 6837
Atlas_Id 52772
Location 9q34.2  [Link to chromosome band 9q34]
Location_base_pair Starts at 133340901 and ends at 133348156 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FN1 (2q35) / MED22 (9q34.2)MED22 (9q34.2) / SURF6 (9q34.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MED22   11477
Cards
Entrez_Gene (NCBI)MED22  6837  mediator complex subunit 22
AliasesMED24; SURF5; surf-5
GeneCards (Weizmann)MED22
Ensembl hg19 (Hinxton)ENSG00000148297 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148297 [Gene_View]  chr9:133340901-133348156 [Contig_View]  MED22 [Vega]
ICGC DataPortalENSG00000148297
TCGA cBioPortalMED22
AceView (NCBI)MED22
Genatlas (Paris)MED22
WikiGenes6837
SOURCE (Princeton)MED22
Genetics Home Reference (NIH)MED22
Genomic and cartography
GoldenPath hg38 (UCSC)MED22  -     chr9:133340901-133348156 -  9q34.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MED22  -     9q34.2   [Description]    (hg19-Feb_2009)
EnsemblMED22 - 9q34.2 [CytoView hg19]  MED22 - 9q34.2 [CytoView hg38]
Mapping of homologs : NCBIMED22 [Mapview hg19]  MED22 [Mapview hg38]
OMIM185641   
Gene and transcription
Genbank (Entrez)AJ224358 AJ224359 AJ224360 AK124518 AK126069
RefSeq transcript (Entrez)NM_006752 NM_133640 NM_181491
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MED22
Cluster EST : UnigeneHs.78354 [ NCBI ]
CGAP (NCI)Hs.78354
Alternative Splicing GalleryENSG00000148297
Gene ExpressionMED22 [ NCBI-GEO ]   MED22 [ EBI - ARRAY_EXPRESS ]   MED22 [ SEEK ]   MED22 [ MEM ]
Gene Expression Viewer (FireBrowse)MED22 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6837
GTEX Portal (Tissue expression)MED22
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15528   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15528  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15528
Splice isoforms : SwissVarQ15528
PhosPhoSitePlusQ15528
Domains : Interpro (EBI)Med22   
Domain families : Pfam (Sanger)Med22 (PF06179)   
Domain families : Pfam (NCBI)pfam06179   
Conserved Domain (NCBI)MED22
DMDM Disease mutations6837
Blocks (Seattle)MED22
SuperfamilyQ15528
Human Protein AtlasENSG00000148297
Peptide AtlasQ15528
HPRD01713
IPIIPI00018040   IPI00219228   IPI00382721   IPI00644426   IPI01012538   IPI00645426   IPI00947131   
Protein Interaction databases
DIP (DOE-UCLA)Q15528
IntAct (EBI)Q15528
FunCoupENSG00000148297
BioGRIDMED22
STRING (EMBL)MED22
ZODIACMED22
Ontologies - Pathways
QuickGOQ15528
Ontology : AmiGORNA polymerase II transcription cofactor activity  protein binding  cytoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  mediator complex  
Ontology : EGO-EBIRNA polymerase II transcription cofactor activity  protein binding  cytoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  mediator complex  
NDEx NetworkMED22
Atlas of Cancer Signalling NetworkMED22
Wikipedia pathwaysMED22
Orthology - Evolution
OrthoDB6837
GeneTree (enSembl)ENSG00000148297
Phylogenetic Trees/Animal Genes : TreeFamMED22
HOVERGENQ15528
HOGENOMQ15528
Homologs : HomoloGeneMED22
Homology/Alignments : Family Browser (UCSC)MED22
Gene fusions - Rearrangements
Fusion Cancer (Beijing)FN1 [2q35]  -  MED22 [9q34.2]  [FUSC002150]  [FUSC002150]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMED22 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MED22
dbVarMED22
ClinVarMED22
1000_GenomesMED22 
Exome Variant ServerMED22
ExAC (Exome Aggregation Consortium)MED22 (select the gene name)
Genetic variants : HAPMAP6837
Genomic Variants (DGV)MED22 [DGVbeta]
DECIPHERMED22 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMED22 
Mutations
ICGC Data PortalMED22 
TCGA Data PortalMED22 
Broad Tumor PortalMED22
OASIS PortalMED22 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMED22  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMED22
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MED22
DgiDB (Drug Gene Interaction Database)MED22
DoCM (Curated mutations)MED22 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MED22 (select a term)
intoGenMED22
Cancer3DMED22(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM185641   
Orphanet
MedgenMED22
Genetic Testing Registry MED22
NextProtQ15528 [Medical]
TSGene6837
GENETestsMED22
Target ValidationMED22
Huge Navigator MED22 [HugePedia]
snp3D : Map Gene to Disease6837
BioCentury BCIQMED22
ClinGenMED22
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6837
Chemical/Pharm GKB GenePA162395486
Clinical trialMED22
Miscellaneous
canSAR (ICR)MED22 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMED22
EVEXMED22
GoPubMedMED22
iHOPMED22
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:06:34 CEST 2017

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