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MED26 (mediator complex subunit 26)

Identity

Alias (NCBI)CRSP7
CRSP70
HGNC (Hugo) MED26
HGNC Alias symbCRSP70
HGNC Previous nameCRSP7
HGNC Previous namecofactor required for Sp1 transcriptional activation, subunit 7, 70kDa
LocusID (NCBI) 9441
Atlas_Id 68878
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 16574919 and ends at 16628204 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CARM1 (19p13.2)::MED26 (19p13.11)MED26 (19p13.11)::CEP164 (11q23.3)MED26 (19p13.11)::KIF18B (17q21.31)
MED26 (19p13.11)::MED26 (19p13.11)MED26 (19p13.11)::USP36 (17q25.3)PTPRJ (11p11.2)::MED26 (19p13.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MED26   2376
Cards
Entrez_Gene (NCBI)MED26    mediator complex subunit 26
AliasesCRSP7; CRSP70
GeneCards (Weizmann)MED26
Ensembl hg19 (Hinxton)ENSG00000105085 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105085 [Gene_View]  ENSG00000105085 [Sequence]  chr19:16574919-16628204 [Contig_View]  MED26 [Vega]
ICGC DataPortalENSG00000105085
TCGA cBioPortalMED26
AceView (NCBI)MED26
Genatlas (Paris)MED26
SOURCE (Princeton)MED26
Genetics Home Reference (NIH)MED26
Genomic and cartography
GoldenPath hg38 (UCSC)MED26  -     chr19:16574919-16628204 -  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MED26  -     19p13.11   [Description]    (hg19-Feb_2009)
GoldenPathMED26 - 19p13.11 [CytoView hg19]  MED26 - 19p13.11 [CytoView hg38]
ImmunoBaseENSG00000105085
Genome Data Viewer NCBIMED26 [Mapview hg19]  
OMIM605043   
Gene and transcription
Genbank (Entrez)AF104253 AK128435 AK313778 BC047040 BC063628
RefSeq transcript (Entrez)NM_004831
Consensus coding sequences : CCDS (NCBI)MED26
Gene ExpressionMED26 [ NCBI-GEO ]   MED26 [ EBI - ARRAY_EXPRESS ]   MED26 [ SEEK ]   MED26 [ MEM ]
Gene Expression Viewer (FireBrowse)MED26 [ Firebrowse - Broad ]
GenevisibleExpression of MED26 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9441
GTEX Portal (Tissue expression)MED26
Human Protein AtlasENSG00000105085-MED26 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95402   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95402  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95402
PhosPhoSitePlusO95402
Domaine pattern : Prosite (Expaxy)TFIIS_N (PS51319)   
Domains : Interpro (EBI)MED26    Med26_C    Med26_Mid    TFIIS/CRSP70_N_sub    TFIIS/LEDGF_dom_sf    TFIIS_N   
Domain families : Pfam (Sanger)Med26 (PF08711)    Med26_C (PF15693)    Med26_M (PF15694)   
Domain families : Pfam (NCBI)pfam08711    pfam15693    pfam15694   
Domain families : Smart (EMBL)TFS2N (SM00509)  
Conserved Domain (NCBI)MED26
PDB (RSDB)5ODD   
PDB Europe5ODD   
PDB (PDBSum)5ODD   
PDB (IMB)5ODD   
Structural Biology KnowledgeBase5ODD   
SCOP (Structural Classification of Proteins)5ODD   
CATH (Classification of proteins structures)5ODD   
SuperfamilyO95402
AlphaFold pdb e-kbO95402   
Human Protein Atlas [tissue]ENSG00000105085-MED26 [tissue]
HPRD05437
Protein Interaction databases
DIP (DOE-UCLA)O95402
IntAct (EBI)O95402
BioGRIDMED26
STRING (EMBL)MED26
ZODIACMED26
Ontologies - Pathways
QuickGOO95402
Ontology : AmiGOtranscription coregulator activity  transcription coregulator activity  transcription coactivator activity  protein binding  nucleoplasm  regulation of transcription by RNA polymerase II  regulation of transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  positive regulation of gene expression  mediator complex  mediator complex  positive regulation of transcription, DNA-templated  regulation of transcription initiation from RNA polymerase II promoter  core mediator complex  
Ontology : EGO-EBItranscription coregulator activity  transcription coregulator activity  transcription coactivator activity  protein binding  nucleoplasm  regulation of transcription by RNA polymerase II  regulation of transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  positive regulation of gene expression  mediator complex  mediator complex  positive regulation of transcription, DNA-templated  regulation of transcription initiation from RNA polymerase II promoter  core mediator complex  
NDEx NetworkMED26
Atlas of Cancer Signalling NetworkMED26
Wikipedia pathwaysMED26
Orthology - Evolution
OrthoDB9441
GeneTree (enSembl)ENSG00000105085
Phylogenetic Trees/Animal Genes : TreeFamMED26
Homologs : HomoloGeneMED26
Homology/Alignments : Family Browser (UCSC)MED26
Gene fusions - Rearrangements
Fusion : QuiverMED26
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMED26 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MED26
dbVarMED26
ClinVarMED26
MonarchMED26
1000_GenomesMED26 
Exome Variant ServerMED26
GNOMAD BrowserENSG00000105085
Varsome BrowserMED26
ACMGMED26 variants
VarityO95402
Genomic Variants (DGV)MED26 [DGVbeta]
DECIPHERMED26 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMED26 
Mutations
ICGC Data PortalMED26 
TCGA Data PortalMED26 
Broad Tumor PortalMED26
OASIS PortalMED26 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMED26  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMED26
Mutations and Diseases : HGMDMED26
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMED26
DgiDB (Drug Gene Interaction Database)MED26
DoCM (Curated mutations)MED26
CIViC (Clinical Interpretations of Variants in Cancer)MED26
Cancer3DMED26
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605043   
Orphanet
DisGeNETMED26
MedgenMED26
Genetic Testing Registry MED26
NextProtO95402 [Medical]
GENETestsMED26
Target ValidationMED26
Huge Navigator MED26 [HugePedia]
ClinGenMED26
Clinical trials, drugs, therapy
MyCancerGenomeMED26
Protein Interactions : CTDMED26
Pharm GKB GenePA162395623
PharosO95402
Clinical trialMED26
Miscellaneous
canSAR (ICR)MED26
HarmonizomeMED26
ARCHS4MED26
DataMed IndexMED26
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMED26
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 13:36:39 CET 2022

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