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MED26 (mediator complex subunit 26)

Identity

Alias_namesCRSP7
cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa
Alias_symbol (synonym)CRSP70
Other alias
HGNC (Hugo) MED26
LocusID (NCBI) 9441
Atlas_Id 68878
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 16574907 and ends at 16628204 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CARM1 (19p13.2) / MED26 (19p13.11)MED26 (19p13.11) / CEP164 (11q23.3)MED26 (19p13.11) / KIF18B (17q21.31)
MED26 (19p13.11) / MED26 (19p13.11)MED26 (19p13.11) / USP36 (17q25.3)PTPRJ (11p11.2) / MED26 (19p13.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MED26   2376
Cards
Entrez_Gene (NCBI)MED26  9441  mediator complex subunit 26
AliasesCRSP7; CRSP70
GeneCards (Weizmann)MED26
Ensembl hg19 (Hinxton)ENSG00000105085 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105085 [Gene_View]  chr19:16574907-16628204 [Contig_View]  MED26 [Vega]
ICGC DataPortalENSG00000105085
TCGA cBioPortalMED26
AceView (NCBI)MED26
Genatlas (Paris)MED26
WikiGenes9441
SOURCE (Princeton)MED26
Genetics Home Reference (NIH)MED26
Genomic and cartography
GoldenPath hg38 (UCSC)MED26  -     chr19:16574907-16628204 -  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MED26  -     19p13.11   [Description]    (hg19-Feb_2009)
EnsemblMED26 - 19p13.11 [CytoView hg19]  MED26 - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBIMED26 [Mapview hg19]  MED26 [Mapview hg38]
OMIM605043   
Gene and transcription
Genbank (Entrez)AF104253 AK128435 AK313778 BC047040 BC063628
RefSeq transcript (Entrez)NM_004831
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MED26
Cluster EST : UnigeneHs.715040 [ NCBI ]
CGAP (NCI)Hs.715040
Alternative Splicing GalleryENSG00000105085
Gene ExpressionMED26 [ NCBI-GEO ]   MED26 [ EBI - ARRAY_EXPRESS ]   MED26 [ SEEK ]   MED26 [ MEM ]
Gene Expression Viewer (FireBrowse)MED26 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9441
GTEX Portal (Tissue expression)MED26
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95402   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95402  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95402
Splice isoforms : SwissVarO95402
PhosPhoSitePlusO95402
Domaine pattern : Prosite (Expaxy)TFIIS_N (PS51319)   
Domains : Interpro (EBI)Med26_C    Med26_Mid    TFIIS/CRSP70_N_sub    TFIIS_N   
Domain families : Pfam (Sanger)Med26 (PF08711)    Med26_C (PF15693)    Med26_M (PF15694)   
Domain families : Pfam (NCBI)pfam08711    pfam15693    pfam15694   
Domain families : Smart (EMBL)TFS2N (SM00509)  
Conserved Domain (NCBI)MED26
DMDM Disease mutations9441
Blocks (Seattle)MED26
PDB (SRS)2MZO   
PDB (PDBSum)2MZO   
PDB (IMB)2MZO   
PDB (RSDB)2MZO   
Structural Biology KnowledgeBase2MZO   
SCOP (Structural Classification of Proteins)2MZO   
CATH (Classification of proteins structures)2MZO   
SuperfamilyO95402
Human Protein AtlasENSG00000105085
Peptide AtlasO95402
HPRD05437
IPIIPI00294682   IPI00827801   
Protein Interaction databases
DIP (DOE-UCLA)O95402
IntAct (EBI)O95402
FunCoupENSG00000105085
BioGRIDMED26
STRING (EMBL)MED26
ZODIACMED26
Ontologies - Pathways
QuickGOO95402
Ontology : AmiGORNA polymerase II transcription cofactor activity  transcription coactivator activity  protein binding  nucleoplasm  regulation of transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  mediator complex  
Ontology : EGO-EBIRNA polymerase II transcription cofactor activity  transcription coactivator activity  protein binding  nucleoplasm  regulation of transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  mediator complex  
NDEx NetworkMED26
Atlas of Cancer Signalling NetworkMED26
Wikipedia pathwaysMED26
Orthology - Evolution
OrthoDB9441
GeneTree (enSembl)ENSG00000105085
Phylogenetic Trees/Animal Genes : TreeFamMED26
HOVERGENO95402
HOGENOMO95402
Homologs : HomoloGeneMED26
Homology/Alignments : Family Browser (UCSC)MED26
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMED26 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MED26
dbVarMED26
ClinVarMED26
1000_GenomesMED26 
Exome Variant ServerMED26
ExAC (Exome Aggregation Consortium)MED26 (select the gene name)
Genetic variants : HAPMAP9441
Genomic Variants (DGV)MED26 [DGVbeta]
DECIPHERMED26 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMED26 
Mutations
ICGC Data PortalMED26 
TCGA Data PortalMED26 
Broad Tumor PortalMED26
OASIS PortalMED26 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMED26  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMED26
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MED26
DgiDB (Drug Gene Interaction Database)MED26
DoCM (Curated mutations)MED26 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MED26 (select a term)
intoGenMED26
Cancer3DMED26(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605043   
Orphanet
MedgenMED26
Genetic Testing Registry MED26
NextProtO95402 [Medical]
TSGene9441
GENETestsMED26
Target ValidationMED26
Huge Navigator MED26 [HugePedia]
snp3D : Map Gene to Disease9441
BioCentury BCIQMED26
ClinGenMED26
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9441
Chemical/Pharm GKB GenePA162395623
Clinical trialMED26
Miscellaneous
canSAR (ICR)MED26 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMED26
EVEXMED26
GoPubMedMED26
iHOPMED26
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:25:47 CEST 2017

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