MED30 (mediator complex subunit 30)

2018-02-01  

Identity

HGNC
LOCATION
8q24.11
LOCUSID
ALIAS
MED30S,THRAP6,TRAP25
FUSION GENES

Other Information

Locus ID:

NCBI: 90390
MIM: 610237
HGNC: 23032
Ensembl: ENSG00000164758

Variants:

dbSNP: 90390
ClinVar: 90390
TCGA: ENSG00000164758
COSMIC: MED30

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164758ENST00000297347Q96HR3
ENSG00000164758ENST00000522839Q96HR3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Thyroid hormone signaling pathwayKEGGhsa04919
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)REACTOMER-HSA-400206
PPARA activates gene expressionREACTOMER-HSA-1989781
Developmental BiologyREACTOMER-HSA-1266738
Transcriptional regulation of white adipocyte differentiationREACTOMER-HSA-381340

References

Pubmed IDYearTitleCitations
119099762002Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s.54
204939792010Mediator subunits: gene expression pattern, a novel transcript identification and nuclear localization in human endothelial progenitor cells.4
291874452017The Contrasting Role of the Mediator Subunit MED30 in the Progression of Bladder Cancer.1
296617222018The knockdown of the mediator complex subunit MED30 suppresses the proliferation and migration of renal cell carcinoma cells.0

Citation

Dessen P

MED30 (mediator complex subunit 30)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57379/med30