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MED31 (mediator complex subunit 31)

Identity

Alias_namesmediator of RNA polymerase II transcription
Alias_symbol (synonym)CGI-125
Soh1
Other alias3110004H13Rik
HGNC (Hugo) MED31
LocusID (NCBI) 51003
Atlas_Id 55504
Location 17p13.1  [Link to chromosome band 17p13]
Location_base_pair Starts at 6643313 and ends at 6651634 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MED31   24260
Cards
Entrez_Gene (NCBI)MED31  51003  mediator complex subunit 31
Aliases3110004H13Rik; CGI-125; Soh1
GeneCards (Weizmann)MED31
Ensembl hg19 (Hinxton)ENSG00000108590 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108590 [Gene_View]  chr17:6643313-6651634 [Contig_View]  MED31 [Vega]
ICGC DataPortalENSG00000108590
TCGA cBioPortalMED31
AceView (NCBI)MED31
Genatlas (Paris)MED31
WikiGenes51003
SOURCE (Princeton)MED31
Genetics Home Reference (NIH)MED31
Genomic and cartography
GoldenPath hg38 (UCSC)MED31  -     chr17:6643313-6651634 -  17p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MED31  -     17p13.1   [Description]    (hg19-Feb_2009)
EnsemblMED31 - 17p13.1 [CytoView hg19]  MED31 - 17p13.1 [CytoView hg38]
Mapping of homologs : NCBIMED31 [Mapview hg19]  MED31 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF151883 AK094033 AK130946 AK311875 BC012539
RefSeq transcript (Entrez)NM_016060
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MED31
Cluster EST : UnigeneHs.567493 [ NCBI ]
CGAP (NCI)Hs.567493
Alternative Splicing GalleryENSG00000108590
Gene ExpressionMED31 [ NCBI-GEO ]   MED31 [ EBI - ARRAY_EXPRESS ]   MED31 [ SEEK ]   MED31 [ MEM ]
Gene Expression Viewer (FireBrowse)MED31 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51003
GTEX Portal (Tissue expression)MED31
Human Protein AtlasENSG00000108590-MED31 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3C7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3C7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3C7
Splice isoforms : SwissVarQ9Y3C7
PhosPhoSitePlusQ9Y3C7
Domains : Interpro (EBI)Mediator_Med31   
Domain families : Pfam (Sanger)Med31 (PF05669)   
Domain families : Pfam (NCBI)pfam05669   
Conserved Domain (NCBI)MED31
DMDM Disease mutations51003
Blocks (Seattle)MED31
SuperfamilyQ9Y3C7
Human Protein Atlas [tissue]ENSG00000108590-MED31 [tissue]
Peptide AtlasQ9Y3C7
HPRD14382
IPIIPI00007021   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3C7
IntAct (EBI)Q9Y3C7
FunCoupENSG00000108590
BioGRIDMED31
STRING (EMBL)MED31
ZODIACMED31
Ontologies - Pathways
QuickGOQ9Y3C7
Ontology : AmiGOubiquitin ligase complex  RNA polymerase II transcription cofactor activity  transcription coactivator activity  protein binding  nucleoplasm  regulation of transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  protein ubiquitination  mediator complex  negative regulation of fibroblast proliferation  limb development  ubiquitin protein ligase activity  core mediator complex  
Ontology : EGO-EBIubiquitin ligase complex  RNA polymerase II transcription cofactor activity  transcription coactivator activity  protein binding  nucleoplasm  regulation of transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  protein ubiquitination  mediator complex  negative regulation of fibroblast proliferation  limb development  ubiquitin protein ligase activity  core mediator complex  
NDEx NetworkMED31
Atlas of Cancer Signalling NetworkMED31
Wikipedia pathwaysMED31
Orthology - Evolution
OrthoDB51003
GeneTree (enSembl)ENSG00000108590
Phylogenetic Trees/Animal Genes : TreeFamMED31
HOVERGENQ9Y3C7
HOGENOMQ9Y3C7
Homologs : HomoloGeneMED31
Homology/Alignments : Family Browser (UCSC)MED31
Gene fusions - Rearrangements
Fusion: Tumor Portal MED31
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMED31 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MED31
dbVarMED31
ClinVarMED31
1000_GenomesMED31 
Exome Variant ServerMED31
ExAC (Exome Aggregation Consortium)ENSG00000108590
GNOMAD BrowserENSG00000108590
Genetic variants : HAPMAP51003
Genomic Variants (DGV)MED31 [DGVbeta]
DECIPHERMED31 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMED31 
Mutations
ICGC Data PortalMED31 
TCGA Data PortalMED31 
Broad Tumor PortalMED31
OASIS PortalMED31 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMED31  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMED31
BioMutasearch MED31
DgiDB (Drug Gene Interaction Database)MED31
DoCM (Curated mutations)MED31 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MED31 (select a term)
intoGenMED31
Cancer3DMED31(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenMED31
Genetic Testing Registry MED31
NextProtQ9Y3C7 [Medical]
TSGene51003
GENETestsMED31
Target ValidationMED31
Huge Navigator MED31 [HugePedia]
snp3D : Map Gene to Disease51003
BioCentury BCIQMED31
ClinGenMED31
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51003
Chemical/Pharm GKB GenePA134884310
Clinical trialMED31
Miscellaneous
canSAR (ICR)MED31 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMED31
EVEXMED31
GoPubMedMED31
iHOPMED31
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:58:29 CET 2017

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