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MEI4 (meiotic double-stranded break formation protein 4)

Identity

Alias_namesmeiosis-specific 4 homolog (S. cerevisiae)
Other alias-
HGNC (Hugo) MEI4
LocusID (NCBI) 101928601
Atlas_Id 68898
Location 6q14.1  [Link to chromosome band 6q14]
Location_base_pair Starts at 77650274 and ends at 77927042 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MEI4   43638
Cards
Entrez_Gene (NCBI)MEI4  101928601  meiotic double-stranded break formation protein 4
Aliases
GeneCards (Weizmann)MEI4
Ensembl hg19 (Hinxton)ENSG00000269964 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000269964 [Gene_View]  ENSG00000269964 [Sequence]  chr6:77650274-77927042 [Contig_View]  MEI4 [Vega]
ICGC DataPortalENSG00000269964
TCGA cBioPortalMEI4
AceView (NCBI)MEI4
Genatlas (Paris)MEI4
WikiGenes101928601
SOURCE (Princeton)MEI4
Genetics Home Reference (NIH)MEI4
Genomic and cartography
GoldenPath hg38 (UCSC)MEI4  -     chr6:77650274-77927042 +  6q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MEI4  -     6q14.1   [Description]    (hg19-Feb_2009)
EnsemblMEI4 - 6q14.1 [CytoView hg19]  MEI4 - 6q14.1 [CytoView hg38]
Mapping of homologs : NCBIMEI4 [Mapview hg19]  MEI4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)CA841124
RefSeq transcript (Entrez)NM_001282136 NM_001322247
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MEI4
Cluster EST : UnigeneHs.544538 [ NCBI ]
CGAP (NCI)Hs.544538
Alternative Splicing GalleryENSG00000269964
Gene ExpressionMEI4 [ NCBI-GEO ]   MEI4 [ EBI - ARRAY_EXPRESS ]   MEI4 [ SEEK ]   MEI4 [ MEM ]
Gene Expression Viewer (FireBrowse)MEI4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)101928601
GTEX Portal (Tissue expression)MEI4
Human Protein AtlasENSG00000269964-MEI4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA8MW99   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA8MW99  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA8MW99
Splice isoforms : SwissVarA8MW99
PhosPhoSitePlusA8MW99
Domains : Interpro (EBI)MEI4   
Domain families : Pfam (Sanger)Mei4 (PF13971)   
Domain families : Pfam (NCBI)pfam13971   
Conserved Domain (NCBI)MEI4
DMDM Disease mutations101928601
Blocks (Seattle)MEI4
SuperfamilyA8MW99
Human Protein Atlas [tissue]ENSG00000269964-MEI4 [tissue]
Peptide AtlasA8MW99
Protein Interaction databases
DIP (DOE-UCLA)A8MW99
IntAct (EBI)A8MW99
FunCoupENSG00000269964
BioGRIDMEI4
STRING (EMBL)MEI4
ZODIACMEI4
Ontologies - Pathways
QuickGOA8MW99
Ontology : AmiGOlateral element  DNA recombination  synapsis  spermatogenesis  meiotic DNA double-strand break formation  oogenesis  
Ontology : EGO-EBIlateral element  DNA recombination  synapsis  spermatogenesis  meiotic DNA double-strand break formation  oogenesis  
NDEx NetworkMEI4
Atlas of Cancer Signalling NetworkMEI4
Wikipedia pathwaysMEI4
Orthology - Evolution
OrthoDB101928601
GeneTree (enSembl)ENSG00000269964
Phylogenetic Trees/Animal Genes : TreeFamMEI4
HOVERGENA8MW99
HOGENOMA8MW99
Homologs : HomoloGeneMEI4
Homology/Alignments : Family Browser (UCSC)MEI4
Gene fusions - Rearrangements
Fusion : QuiverMEI4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMEI4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MEI4
dbVarMEI4
ClinVarMEI4
1000_GenomesMEI4 
Exome Variant ServerMEI4
ExAC (Exome Aggregation Consortium)ENSG00000269964
GNOMAD BrowserENSG00000269964
Varsome BrowserMEI4
Genetic variants : HAPMAP101928601
Genomic Variants (DGV)MEI4 [DGVbeta]
DECIPHERMEI4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMEI4 
Mutations
ICGC Data PortalMEI4 
TCGA Data PortalMEI4 
Broad Tumor PortalMEI4
OASIS PortalMEI4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMEI4
BioMutasearch MEI4
DgiDB (Drug Gene Interaction Database)MEI4
DoCM (Curated mutations)MEI4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MEI4 (select a term)
intoGenMEI4
Cancer3DMEI4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETMEI4
MedgenMEI4
Genetic Testing Registry MEI4
NextProtA8MW99 [Medical]
TSGene101928601
GENETestsMEI4
Target ValidationMEI4
Huge Navigator MEI4 [HugePedia]
snp3D : Map Gene to Disease101928601
BioCentury BCIQMEI4
ClinGenMEI4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD101928601
Chemical/Pharm GKB GenePA166123702
Clinical trialMEI4
Miscellaneous
canSAR (ICR)MEI4 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMEI4
EVEXMEI4
GoPubMedMEI4
iHOPMEI4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:12:38 CEST 2018

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