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MEIS3 (Meis homeobox 3)

Identity

Alias_namesMeis1
Alias_symbol (synonym)MRG2
DKFZp547H236
Other alias
HGNC (Hugo) MEIS3
LocusID (NCBI) 56917
Atlas_Id 56209
Location 19q13.32  [Link to chromosome band 19q13]
Location_base_pair Starts at 47403118 and ends at 47419528 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACTG1 (17q25.3) / MEIS3 (19q13.32)MEIS3 (19q13.32) / TSIX (Xq13.2)SLC8A3 (14q24.2) / MEIS3 (19q13.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MEIS3   29537
Cards
Entrez_Gene (NCBI)MEIS3  56917  Meis homeobox 3
AliasesMRG2
GeneCards (Weizmann)MEIS3
Ensembl hg19 (Hinxton)ENSG00000105419 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105419 [Gene_View]  chr19:47403118-47419528 [Contig_View]  MEIS3 [Vega]
ICGC DataPortalENSG00000105419
TCGA cBioPortalMEIS3
AceView (NCBI)MEIS3
Genatlas (Paris)MEIS3
WikiGenes56917
SOURCE (Princeton)MEIS3
Genetics Home Reference (NIH)MEIS3
Genomic and cartography
GoldenPath hg38 (UCSC)MEIS3  -     chr19:47403118-47419528 -  19q13.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MEIS3  -     19q13.32   [Description]    (hg19-Feb_2009)
EnsemblMEIS3 - 19q13.32 [CytoView hg19]  MEIS3 - 19q13.32 [CytoView hg38]
Mapping of homologs : NCBIMEIS3 [Mapview hg19]  MEIS3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB209455 AK098710 AK289950 AL537583 AY091593
RefSeq transcript (Entrez)NM_001009813 NM_001301059 NM_001346148 NM_020160
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MEIS3
Cluster EST : UnigeneHs.380923 [ NCBI ]
CGAP (NCI)Hs.380923
Alternative Splicing GalleryENSG00000105419
Gene ExpressionMEIS3 [ NCBI-GEO ]   MEIS3 [ EBI - ARRAY_EXPRESS ]   MEIS3 [ SEEK ]   MEIS3 [ MEM ]
Gene Expression Viewer (FireBrowse)MEIS3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56917
GTEX Portal (Tissue expression)MEIS3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99687   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99687  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99687
Splice isoforms : SwissVarQ99687
PhosPhoSitePlusQ99687
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_dom    Homeobox_KN_domain    PKNOX/Meis_N   
Domain families : Pfam (Sanger)Homeobox_KN (PF05920)    Meis_PKNOX_N (PF16493)   
Domain families : Pfam (NCBI)pfam05920    pfam16493   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)MEIS3
DMDM Disease mutations56917
Blocks (Seattle)MEIS3
SuperfamilyQ99687
Human Protein AtlasENSG00000105419
Peptide AtlasQ99687
HPRD14386
IPIIPI00549724   IPI00456373   IPI00216162   IPI00555575   
Protein Interaction databases
DIP (DOE-UCLA)Q99687
IntAct (EBI)Q99687
FunCoupENSG00000105419
BioGRIDMEIS3
STRING (EMBL)MEIS3
ZODIACMEIS3
Ontologies - Pathways
QuickGOQ99687
Ontology : AmiGOtranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  chromatin binding  nucleus  transcription from RNA polymerase II promoter  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  positive regulation of protein kinase B signaling  negative regulation of apoptotic signaling pathway  
Ontology : EGO-EBItranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  chromatin binding  nucleus  transcription from RNA polymerase II promoter  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  positive regulation of protein kinase B signaling  negative regulation of apoptotic signaling pathway  
NDEx NetworkMEIS3
Atlas of Cancer Signalling NetworkMEIS3
Wikipedia pathwaysMEIS3
Orthology - Evolution
OrthoDB56917
GeneTree (enSembl)ENSG00000105419
Phylogenetic Trees/Animal Genes : TreeFamMEIS3
HOVERGENQ99687
HOGENOMQ99687
Homologs : HomoloGeneMEIS3
Homology/Alignments : Family Browser (UCSC)MEIS3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMEIS3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MEIS3
dbVarMEIS3
ClinVarMEIS3
1000_GenomesMEIS3 
Exome Variant ServerMEIS3
ExAC (Exome Aggregation Consortium)MEIS3 (select the gene name)
Genetic variants : HAPMAP56917
Genomic Variants (DGV)MEIS3 [DGVbeta]
DECIPHERMEIS3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMEIS3 
Mutations
ICGC Data PortalMEIS3 
TCGA Data PortalMEIS3 
Broad Tumor PortalMEIS3
OASIS PortalMEIS3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMEIS3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMEIS3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MEIS3
DgiDB (Drug Gene Interaction Database)MEIS3
DoCM (Curated mutations)MEIS3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MEIS3 (select a term)
intoGenMEIS3
Cancer3DMEIS3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenMEIS3
Genetic Testing Registry MEIS3
NextProtQ99687 [Medical]
TSGene56917
GENETestsMEIS3
Target ValidationMEIS3
Huge Navigator MEIS3 [HugePedia]
snp3D : Map Gene to Disease56917
BioCentury BCIQMEIS3
ClinGenMEIS3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56917
Chemical/Pharm GKB GenePA30742
Clinical trialMEIS3
Miscellaneous
canSAR (ICR)MEIS3 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMEIS3
EVEXMEIS3
GoPubMedMEIS3
iHOPMEIS3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:17:43 CEST 2017

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