MEOX1 (mesenchyme homeobox 1)

2003-02-01  

Identity

HGNC
MEOX1
LOCATION
17q21.31
LOCUSID
4222
ALIAS
KFS2,MOX1

Other Information

Locus ID:

NCBI: 4222
MIM: 600147
HGNC: 7013
Ensembl: ENSG00000005102

Variants:

dbSNP: 4222
ClinVar: 4222
TCGA: ENSG00000005102
COSMIC: MEOX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000005102ENST00000318579P50221
ENSG00000005102ENST00000393661P50221
ENSG00000005102ENST00000549132F8VXS6

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
225671232012Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites.16
232900722013Mutations in MEOX1, encoding mesenchyme homeobox 1, cause Klippel-Feil anomaly.14
272859822016Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer.14
240739942013Mutation in MEOX1 gene causes a recessive Klippel-Feil syndrome subtype.8
177640812007Diaphanospondylodysostosis: six new cases and exclusion of the candidate genes, PAX1 and MEOX1.4
306623302019MEOX1 Promotes Tumor Progression and Predicts Poor Prognosis in Human Non-Small-Cell Lung Cancer.2
305434602019Silencing of MEOX1 Gene Inhibits Proliferation and Promotes Apoptosis of LNCaP Cells in Prostate Cancer.0
322410492020[Mechanism of transcriptional regulation of Meox1 by transforming growth factor β (1) and its effect on cell migration of adult human dermal fibroblasts].0

Citation

Dessen P

MEOX1 (mesenchyme homeobox 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41335/meox1