MEP1B (meprin A, beta)

Identity

Other names	-
HGNC	MEP1B
Location	18q12.2-q12.3
Location_base_pair	Starts at 28023985 and ends at 28054364 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	MEP1B   7020
Entrez_Gene	MEP1B  4225  meprin A, beta
	Cards
GeneCards	MEP1B
Ensembl	MEP1B [Search_View]   ENSG00000112818 [Gene_View]
Genatlas	MEP1B
GeneLynx	MEP1B
eGenome	MEP1B
euGene	4225
	Genomic and cartography
GoldenPath	MEP1B  -     chr18:28023985-28054364 +  18q12.1   [Description]    (hg18-March_2006)
Ensembl	MEP1B - 18q12.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	MEP1B
	Gene and transcription
Genbank	AY695931 [ ENTREZ ]
Genbank	X81333 [ ENTREZ ]
RefSeq	NM_005925 [ SRS ]    NM_005925 [ ENTREZ ]
RefSeq	AC_000061 [ SRS ]    AC_000061 [ ENTREZ ]
RefSeq	AC_000150 [ SRS ]    AC_000150 [ ENTREZ ]
RefSeq	NC_000018 [ SRS ]    NC_000018 [ ENTREZ ]
RefSeq	NT_010966 [ SRS ]    NT_010966 [ ENTREZ ]
RefSeq	NW_001838467 [ SRS ]    NW_001838467 [ ENTREZ ]
RefSeq	NW_927095 [ SRS ]    NW_927095 [ ENTREZ ]
AceView	MEP1B AceView - NCBI
Unigene	Hs.194777 [ SRS ]    Hs.194777 [ NCBI ]     HS194777 [ spliceNest ]
Fast-db	3219 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q16820 [ SRS]    Q16820 [ EXPASY ]     Q16820 [ INTERPRO ]     Q16820 [ UNIPROT ]
Prosite	PS00022 EGF_1 [ SRS ]    PS00022 EGF_1 [ Expasy ]
Prosite	PS01186 EGF_2 [ SRS ]    PS01186 EGF_2 [ Expasy ]
Prosite	PS50026 EGF_3 [ SRS ]    PS50026 EGF_3 [ Expasy ]
Prosite	PS00740 MAM_1 [ SRS ]    PS00740 MAM_1 [ Expasy ]
Prosite	PS50060 MAM_2 [ SRS ]    PS50060 MAM_2 [ Expasy ]
Prosite	PS50144 MATH [ SRS ]    PS50144 MATH [ Expasy ]
Prosite	PS00142 ZINC_PROTEASE [ SRS ]    PS00142 ZINC_PROTEASE [ Expasy ]
Interpro	IPR006210 EGF [ SRS ]    IPR006210 EGF [ EBI ]
Interpro	IPR000742 EGF_3 [ SRS ]    IPR000742 EGF_3 [ EBI ]
Interpro	IPR006209 EGF_like [ SRS ]    IPR006209 EGF_like [ EBI ]
Interpro	IPR013032 EGF_like_reg_CS [ SRS ]    IPR013032 EGF_like_reg_CS [ EBI ]
Interpro	IPR000998 MAM [ SRS ]    IPR000998 MAM [ EBI ]
Interpro	IPR002083 MATH [ SRS ]    IPR002083 MATH [ EBI ]
Interpro	IPR008294 Pept_M12A_Meprin [ SRS ]    IPR008294 Pept_M12A_Meprin [ EBI ]
Interpro	IPR006025 Pept_M_Zn_BS [ SRS ]    IPR006025 Pept_M_Zn_BS [ EBI ]
Interpro	IPR006026 Peptidase_M [ SRS ]    IPR006026 Peptidase_M [ EBI ]
Interpro	IPR001506 Peptidase_M12A [ SRS ]    IPR001506 Peptidase_M12A [ EBI ]
Interpro	IPR013322 TRAF-type [ SRS ]    IPR013322 TRAF-type [ EBI ]
CluSTr	Q16820
Pfam	PF01400 Astacin [ SRS ]    PF01400 Astacin [ Sanger ]    pfam01400 [ NCBI-CDD ]
Pfam	PF00008 EGF [ SRS ]    PF00008 EGF [ Sanger ]    pfam00008 [ NCBI-CDD ]
Pfam	PF00629 MAM [ SRS ]    PF00629 MAM [ Sanger ]    pfam00629 [ NCBI-CDD ]
Pfam	PF00917 MATH [ SRS ]    PF00917 MATH [ Sanger ]    pfam00917 [ NCBI-CDD ]
Smart	SM00181 EGF [EMBL]
Smart	SM00137 MAM [EMBL]
Smart	SM00061 MATH [EMBL]
Smart	SM00235 ZnMc [EMBL]
Blocks	Q16820
HPRD	02667
	Protein Interaction databases
DIP	Q16820
IntAct	Q16820
	Polymorphism : SNP, mutations, diseases
OMIM	600389    [ map ]
GENECLINICS	600389
SNP	MEP1B [dbSNP-NCBI]
SNP	NM_005925 [SNP-NCI]
SNP	MEP1B [GeneSNPs - Utah]  MEP1B] [HGBASE - SRS]
HAPMAP	MEP1B [HAPMAP]
HGMD	MEP1B
	General knowledge
Family Browser	MEP1B [UCSC Family Browser]
SOURCE	NM_005925
SMD	Hs.194777
SAGE	Hs.194777
Enzyme	3.4.24.18 [ Enzyme-Expasy ]   3.4.24.18 [ Enzyme-SRS ]   3.4.24.18 [ IntEnz-EBI ]   3.4.24.18 [ BRENDA ]   3.4.24.18 [ KEGG ]   3.4.24.18 [ WIT ]
GO	meprin A activity [Amigo]  meprin A activity
GO	extracellular space [Amigo]  extracellular space
GO	plasma membrane [Amigo]  plasma membrane
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	proteolysis [Amigo]  proteolysis
GO	digestion [Amigo]  digestion
GO	metallopeptidase activity [Amigo]  metallopeptidase activity
GO	zinc ion binding [Amigo]  zinc ion binding
GO	astacin activity [Amigo]  astacin activity
GO	metal ion binding [Amigo]  metal ion binding
PubGene	MEP1B
TreeFam	MEP1B
CTD	4225 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	MEP1B Related clones (RZPD - Berlin)
	PubMed
PubMed	18 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:50:20 2008