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MEPCE (methylphosphate capping enzyme)

Identity

Alias_namesBCDIN3
bin3, bicoid-interacting 3, homolog (Drosophila)
Alias_symbol (synonym)FLJ20257
MePCE
Other alias
HGNC (Hugo) MEPCE
LocusID (NCBI) 56257
Atlas_Id 68904
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 100428790 and ends at 100434126 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACTG1 (17q25.3) / MEPCE (7q22.1)MEPCE (7q22.1) / MEPCE (7q22.1)STX3 (11q12.1) / MEPCE (7q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MEPCE   20247
Cards
Entrez_Gene (NCBI)MEPCE  56257  methylphosphate capping enzyme
AliasesBCDIN3
GeneCards (Weizmann)MEPCE
Ensembl hg19 (Hinxton)ENSG00000146834 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146834 [Gene_View]  chr7:100428790-100434126 [Contig_View]  MEPCE [Vega]
ICGC DataPortalENSG00000146834
TCGA cBioPortalMEPCE
AceView (NCBI)MEPCE
Genatlas (Paris)MEPCE
WikiGenes56257
SOURCE (Princeton)MEPCE
Genetics Home Reference (NIH)MEPCE
Genomic and cartography
GoldenPath hg38 (UCSC)MEPCE  -     chr7:100428790-100434126 +  7q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MEPCE  -     7q22.1   [Description]    (hg19-Feb_2009)
EnsemblMEPCE - 7q22.1 [CytoView hg19]  MEPCE - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBIMEPCE [Mapview hg19]  MEPCE [Mapview hg38]
OMIM611478   
Gene and transcription
Genbank (Entrez)AI432993 AK000264 AK055964 AK291366 BC000556
RefSeq transcript (Entrez)NM_001194990 NM_001194991 NM_001194992 NM_019606
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MEPCE
Cluster EST : UnigeneHs.178011 [ NCBI ]
CGAP (NCI)Hs.178011
Alternative Splicing GalleryENSG00000146834
Gene ExpressionMEPCE [ NCBI-GEO ]   MEPCE [ EBI - ARRAY_EXPRESS ]   MEPCE [ SEEK ]   MEPCE [ MEM ]
Gene Expression Viewer (FireBrowse)MEPCE [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56257
GTEX Portal (Tissue expression)MEPCE
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L2J0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L2J0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L2J0
Splice isoforms : SwissVarQ7L2J0
Catalytic activity : Enzyme2.1.1.- [ Enzyme-Expasy ]   2.1.1.-2.1.1.- [ IntEnz-EBI ]   2.1.1.- [ BRENDA ]   2.1.1.- [ KEGG ]   
PhosPhoSitePlusQ7L2J0
Domaine pattern : Prosite (Expaxy)BIN3_SAM (PS51515)   
Domains : Interpro (EBI)Bin3_C    BIN3_SAM-bd_dom    Methyltranfer_dom    SAM-dependent_MTases   
Domain families : Pfam (Sanger)Bin3 (PF06859)    Methyltransf_31 (PF13847)   
Domain families : Pfam (NCBI)pfam06859    pfam13847   
Conserved Domain (NCBI)MEPCE
DMDM Disease mutations56257
Blocks (Seattle)MEPCE
PDB (SRS)3G07   
PDB (PDBSum)3G07   
PDB (IMB)3G07   
PDB (RSDB)3G07   
Structural Biology KnowledgeBase3G07   
SCOP (Structural Classification of Proteins)3G07   
CATH (Classification of proteins structures)3G07   
SuperfamilyQ7L2J0
Human Protein AtlasENSG00000146834
Peptide AtlasQ7L2J0
HPRD07889
IPIIPI00021320   IPI00924881   
Protein Interaction databases
DIP (DOE-UCLA)Q7L2J0
IntAct (EBI)Q7L2J0
FunCoupENSG00000146834
BioGRIDMEPCE
STRING (EMBL)MEPCE
ZODIACMEPCE
Ontologies - Pathways
QuickGOQ7L2J0
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA methylation  RNA binding  RNA methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  snRNA metabolic process  negative regulation of chromatin binding  snRNA modification  positive regulation of G1/S transition of mitotic cell cycle  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA methylation  RNA binding  RNA methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  snRNA metabolic process  negative regulation of chromatin binding  snRNA modification  positive regulation of G1/S transition of mitotic cell cycle  
NDEx NetworkMEPCE
Atlas of Cancer Signalling NetworkMEPCE
Wikipedia pathwaysMEPCE
Orthology - Evolution
OrthoDB56257
GeneTree (enSembl)ENSG00000146834
Phylogenetic Trees/Animal Genes : TreeFamMEPCE
HOVERGENQ7L2J0
HOGENOMQ7L2J0
Homologs : HomoloGeneMEPCE
Homology/Alignments : Family Browser (UCSC)MEPCE
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMEPCE [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MEPCE
dbVarMEPCE
ClinVarMEPCE
1000_GenomesMEPCE 
Exome Variant ServerMEPCE
ExAC (Exome Aggregation Consortium)MEPCE (select the gene name)
Genetic variants : HAPMAP56257
Genomic Variants (DGV)MEPCE [DGVbeta]
DECIPHERMEPCE [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMEPCE 
Mutations
ICGC Data PortalMEPCE 
TCGA Data PortalMEPCE 
Broad Tumor PortalMEPCE
OASIS PortalMEPCE [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMEPCE  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMEPCE
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MEPCE
DgiDB (Drug Gene Interaction Database)MEPCE
DoCM (Curated mutations)MEPCE (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MEPCE (select a term)
intoGenMEPCE
Cancer3DMEPCE(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611478   
Orphanet
MedgenMEPCE
Genetic Testing Registry MEPCE
NextProtQ7L2J0 [Medical]
TSGene56257
GENETestsMEPCE
Target ValidationMEPCE
Huge Navigator MEPCE [HugePedia]
snp3D : Map Gene to Disease56257
BioCentury BCIQMEPCE
ClinGenMEPCE
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56257
Chemical/Pharm GKB GenePA162395768
Clinical trialMEPCE
Miscellaneous
canSAR (ICR)MEPCE (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMEPCE
EVEXMEPCE
GoPubMedMEPCE
iHOPMEPCE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:25:52 CEST 2017

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