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MESDC2 (mesoderm development candidate 2)

Identity

Alias_symbol (synonym)KIAA0081
BOCA
MESD
Other alias
HGNC (Hugo) MESDC2
LocusID (NCBI) 23184
Atlas_Id 46073
Location 15q25.1  [Link to chromosome band 15q25]
Location_base_pair Starts at 80975745 and ends at 80989878 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACVR1C (2q24.1) / MESDC2 (15q25.1)IL22RA1 (1p36.11) / MESDC2 (15q25.1)MESDC2 (15q25.1) / CASK (Xp11.4)
SENP1 (12q13.11) / MESDC2 (15q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MESDC2   13520
Cards
Entrez_Gene (NCBI)MESDC2  23184  mesoderm development candidate 2
AliasesBOCA; MESD
GeneCards (Weizmann)MESDC2
Ensembl hg19 (Hinxton)ENSG00000117899 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117899 [Gene_View]  chr15:80975745-80989878 [Contig_View]  MESDC2 [Vega]
ICGC DataPortalENSG00000117899
TCGA cBioPortalMESDC2
AceView (NCBI)MESDC2
Genatlas (Paris)MESDC2
WikiGenes23184
SOURCE (Princeton)MESDC2
Genetics Home Reference (NIH)MESDC2
Genomic and cartography
GoldenPath hg38 (UCSC)MESDC2  -     chr15:80975745-80989878 -  15q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MESDC2  -     15q25.1   [Description]    (hg19-Feb_2009)
EnsemblMESDC2 - 15q25.1 [CytoView hg19]  MESDC2 - 15q25.1 [CytoView hg38]
Mapping of homologs : NCBIMESDC2 [Mapview hg19]  MESDC2 [Mapview hg38]
OMIM607783   
Gene and transcription
Genbank (Entrez)AI911839 AK026606 AK301416 AY359110 BC007867
RefSeq transcript (Entrez)NM_015154
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MESDC2
Cluster EST : UnigeneHs.732380 [ NCBI ]
CGAP (NCI)Hs.732380
Alternative Splicing GalleryENSG00000117899
Gene ExpressionMESDC2 [ NCBI-GEO ]   MESDC2 [ EBI - ARRAY_EXPRESS ]   MESDC2 [ SEEK ]   MESDC2 [ MEM ]
Gene Expression Viewer (FireBrowse)MESDC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23184
GTEX Portal (Tissue expression)MESDC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14696   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14696  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14696
Splice isoforms : SwissVarQ14696
PhosPhoSitePlusQ14696
Domains : Interpro (EBI)Mesoderm_development_cand-2   
Domain families : Pfam (Sanger)Mesd (PF10185)   
Domain families : Pfam (NCBI)pfam10185   
Conserved Domain (NCBI)MESDC2
DMDM Disease mutations23184
Blocks (Seattle)MESDC2
SuperfamilyQ14696
Human Protein AtlasENSG00000117899
Peptide AtlasQ14696
HPRD12129
IPIIPI00399089   IPI00796904   
Protein Interaction databases
DIP (DOE-UCLA)Q14696
IntAct (EBI)Q14696
FunCoupENSG00000117899
BioGRIDMESDC2
STRING (EMBL)MESDC2
ZODIACMESDC2
Ontologies - Pathways
QuickGOQ14696
Ontology : AmiGOmolecular_function  cellular_component  endoplasmic reticulum  plasma membrane  protein folding  mesoderm development  Wnt signaling pathway  protein localization to cell surface  low-density lipoprotein particle receptor binding  
Ontology : EGO-EBImolecular_function  cellular_component  endoplasmic reticulum  plasma membrane  protein folding  mesoderm development  Wnt signaling pathway  protein localization to cell surface  low-density lipoprotein particle receptor binding  
NDEx NetworkMESDC2
Atlas of Cancer Signalling NetworkMESDC2
Wikipedia pathwaysMESDC2
Orthology - Evolution
OrthoDB23184
GeneTree (enSembl)ENSG00000117899
Phylogenetic Trees/Animal Genes : TreeFamMESDC2
HOVERGENQ14696
HOGENOMQ14696
Homologs : HomoloGeneMESDC2
Homology/Alignments : Family Browser (UCSC)MESDC2
Gene fusions - Rearrangements
Fusion : MitelmanMESDC2/CASK [15q25.1/Xp11.4]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMESDC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MESDC2
dbVarMESDC2
ClinVarMESDC2
1000_GenomesMESDC2 
Exome Variant ServerMESDC2
ExAC (Exome Aggregation Consortium)MESDC2 (select the gene name)
Genetic variants : HAPMAP23184
Genomic Variants (DGV)MESDC2 [DGVbeta]
DECIPHERMESDC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMESDC2 
Mutations
ICGC Data PortalMESDC2 
TCGA Data PortalMESDC2 
Broad Tumor PortalMESDC2
OASIS PortalMESDC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMESDC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMESDC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MESDC2
DgiDB (Drug Gene Interaction Database)MESDC2
DoCM (Curated mutations)MESDC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MESDC2 (select a term)
intoGenMESDC2
Cancer3DMESDC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607783   
Orphanet
MedgenMESDC2
Genetic Testing Registry MESDC2
NextProtQ14696 [Medical]
TSGene23184
GENETestsMESDC2
Target ValidationMESDC2
Huge Navigator MESDC2 [HugePedia]
snp3D : Map Gene to Disease23184
BioCentury BCIQMESDC2
ClinGenMESDC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23184
Chemical/Pharm GKB GenePA30761
Clinical trialMESDC2
Miscellaneous
canSAR (ICR)MESDC2 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMESDC2
EVEXMESDC2
GoPubMedMESDC2
iHOPMESDC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:42:48 CEST 2017

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