Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MESP2 (mesoderm posterior bHLH transcription factor 2)

Identity

Alias_namesmesoderm posterior 2 homolog (mouse)
mesoderm posterior basic helix-loop-helix transcription factor 2
Alias_symbol (synonym)SCDO2
bHLHc6
Other alias
HGNC (Hugo) MESP2
LocusID (NCBI) 145873
Atlas_Id 50437
Location 15q26.1  [Link to chromosome band 15q26]
Location_base_pair Starts at 89776358 and ends at 89778751 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IQGAP1 (15q26.1) / MESP2 (15q26.1)MAN2C1 (15q24.2) / MESP2 (15q26.1)IQGAP1 15q26.1 / MESP2 15q26.1
MAN2C1 15q24.2 / MESP2 15q26.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MESP2   29659
Cards
Entrez_Gene (NCBI)MESP2  145873  mesoderm posterior bHLH transcription factor 2
AliasesSCDO2; bHLHc6
GeneCards (Weizmann)MESP2
Ensembl hg19 (Hinxton)ENSG00000188095 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188095 [Gene_View]  chr15:89776358-89778751 [Contig_View]  MESP2 [Vega]
ICGC DataPortalENSG00000188095
TCGA cBioPortalMESP2
AceView (NCBI)MESP2
Genatlas (Paris)MESP2
WikiGenes145873
SOURCE (Princeton)MESP2
Genetics Home Reference (NIH)MESP2
Genomic and cartography
GoldenPath hg38 (UCSC)MESP2  -     chr15:89776358-89778751 +  15q26.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MESP2  -     15q26.1   [Description]    (hg19-Feb_2009)
EnsemblMESP2 - 15q26.1 [CytoView hg19]  MESP2 - 15q26.1 [CytoView hg38]
Mapping of homologs : NCBIMESP2 [Mapview hg19]  MESP2 [Mapview hg38]
OMIM277300   605195   608681   
Gene and transcription
Genbank (Entrez)AL360139 BC111413
RefSeq transcript (Entrez)NM_001039958
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MESP2
Cluster EST : UnigeneHs.37311 [ NCBI ]
CGAP (NCI)Hs.37311
Alternative Splicing GalleryENSG00000188095
Gene ExpressionMESP2 [ NCBI-GEO ]   MESP2 [ EBI - ARRAY_EXPRESS ]   MESP2 [ SEEK ]   MESP2 [ MEM ]
Gene Expression Viewer (FireBrowse)MESP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)145873
GTEX Portal (Tissue expression)MESP2
Human Protein AtlasENSG00000188095-MESP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ0VG99   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ0VG99  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ0VG99
Splice isoforms : SwissVarQ0VG99
PhosPhoSitePlusQ0VG99
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)MESP2
DMDM Disease mutations145873
Blocks (Seattle)MESP2
SuperfamilyQ0VG99
Human Protein Atlas [tissue]ENSG00000188095-MESP2 [tissue]
Peptide AtlasQ0VG99
IPIIPI00394925   
Protein Interaction databases
DIP (DOE-UCLA)Q0VG99
IntAct (EBI)Q0VG99
FunCoupENSG00000188095
BioGRIDMESP2
STRING (EMBL)MESP2
ZODIACMESP2
Ontologies - Pathways
QuickGOQ0VG99
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  mesoderm formation  somitogenesis  heart morphogenesis  nucleus  transcription from RNA polymerase II promoter  Notch signaling pathway  embryonic pattern specification  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  extracellular exosome  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  mesoderm formation  somitogenesis  heart morphogenesis  nucleus  transcription from RNA polymerase II promoter  Notch signaling pathway  embryonic pattern specification  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  extracellular exosome  
NDEx NetworkMESP2
Atlas of Cancer Signalling NetworkMESP2
Wikipedia pathwaysMESP2
Orthology - Evolution
OrthoDB145873
GeneTree (enSembl)ENSG00000188095
Phylogenetic Trees/Animal Genes : TreeFamMESP2
HOVERGENQ0VG99
HOGENOMQ0VG99
Homologs : HomoloGeneMESP2
Homology/Alignments : Family Browser (UCSC)MESP2
Gene fusions - Rearrangements
Fusion : MitelmanIQGAP1/MESP2 [15q26.1/15q26.1]  [t(15;15)(q26;q26)]  
Fusion : MitelmanMAN2C1/MESP2 [15q24.2/15q26.1]  [t(15;15)(q24;q26)]  
Fusion: TCGA_MDACCIQGAP1 15q26.1 MESP2 15q26.1 BRCA
Fusion: TCGA_MDACCMAN2C1 15q24.2 MESP2 15q26.1 PRAD
Tumor Fusion PortalMESP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMESP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MESP2
dbVarMESP2
ClinVarMESP2
1000_GenomesMESP2 
Exome Variant ServerMESP2
ExAC (Exome Aggregation Consortium)ENSG00000188095
GNOMAD BrowserENSG00000188095
Genetic variants : HAPMAP145873
Genomic Variants (DGV)MESP2 [DGVbeta]
DECIPHERMESP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMESP2 
Mutations
ICGC Data PortalMESP2 
TCGA Data PortalMESP2 
Broad Tumor PortalMESP2
OASIS PortalMESP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMESP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMESP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MESP2
DgiDB (Drug Gene Interaction Database)MESP2
DoCM (Curated mutations)MESP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MESP2 (select a term)
intoGenMESP2
Cancer3DMESP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM277300    605195    608681   
Orphanet1042   
DisGeNETMESP2
MedgenMESP2
Genetic Testing Registry MESP2
NextProtQ0VG99 [Medical]
TSGene145873
GENETestsMESP2
Target ValidationMESP2
Huge Navigator MESP2 [HugePedia]
snp3D : Map Gene to Disease145873
BioCentury BCIQMESP2
ClinGenMESP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD145873
Chemical/Pharm GKB GenePA142671469
Clinical trialMESP2
Miscellaneous
canSAR (ICR)MESP2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMESP2
EVEXMESP2
GoPubMedMESP2
iHOPMESP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:22:10 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.