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MEST (mesoderm specific transcript)

Identity

Alias_namesmesoderm specific transcript (mouse) homolog
mesoderm specific transcript homolog (mouse)
Alias_symbol (synonym)PEG1
Other alias
HGNC (Hugo) MEST
LocusID (NCBI) 4232
Atlas_Id 41340
Location 7q32.2  [Link to chromosome band 7q32]
Location_base_pair Starts at 130492058 and ends at 130506297 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LDHA (11p15.1) / MEST (7q32.2)MEST (7q32.2) / ATP6V0A1 (17q21.2)MEST (7q32.2) / CERS6 (2q24.3)
MEST (7q32.2) / MEST (7q32.2)SPTAN1 (9q34.11) / MEST (7q32.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MEST   7028
LRG (Locus Reference Genomic)LRG_1033
Cards
Entrez_Gene (NCBI)MEST  4232  mesoderm specific transcript
AliasesPEG1
GeneCards (Weizmann)MEST
Ensembl hg19 (Hinxton)ENSG00000106484 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106484 [Gene_View]  chr7:130492058-130506297 [Contig_View]  MEST [Vega]
ICGC DataPortalENSG00000106484
TCGA cBioPortalMEST
AceView (NCBI)MEST
Genatlas (Paris)MEST
WikiGenes4232
SOURCE (Princeton)MEST
Genetics Home Reference (NIH)MEST
Genomic and cartography
GoldenPath hg38 (UCSC)MEST  -     chr7:130492058-130506297 +  7q32.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MEST  -     7q32.2   [Description]    (hg19-Feb_2009)
EnsemblMEST - 7q32.2 [CytoView hg19]  MEST - 7q32.2 [CytoView hg38]
Mapping of homologs : NCBIMEST [Mapview hg19]  MEST [Mapview hg38]
OMIM601029   
Gene and transcription
Genbank (Entrez)AA728839 AK098397 AK298984 AK312688 AU118070
RefSeq transcript (Entrez)NM_001253900 NM_001253901 NM_001253902 NM_002402 NM_177524 NM_177525
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MEST
Cluster EST : UnigeneHs.270978 [ NCBI ]
CGAP (NCI)Hs.270978
Alternative Splicing GalleryENSG00000106484
Gene ExpressionMEST [ NCBI-GEO ]   MEST [ EBI - ARRAY_EXPRESS ]   MEST [ SEEK ]   MEST [ MEM ]
Gene Expression Viewer (FireBrowse)MEST [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4232
GTEX Portal (Tissue expression)MEST
Human Protein AtlasENSG00000106484-MEST [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5EB52   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5EB52  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5EB52
Splice isoforms : SwissVarQ5EB52
Catalytic activity : Enzyme3.-.-.- [ Enzyme-Expasy ]   3.-.-.-3.-.-.- [ IntEnz-EBI ]   3.-.-.- [ BRENDA ]   3.-.-.- [ KEGG ]   
PhosPhoSitePlusQ5EB52
Domains : Interpro (EBI)AB_hydrolase    AB_hydrolase_1    Epox_hydrolase-like   
Domain families : Pfam (Sanger)Abhydrolase_1 (PF00561)   
Domain families : Pfam (NCBI)pfam00561   
Conserved Domain (NCBI)MEST
DMDM Disease mutations4232
Blocks (Seattle)MEST
SuperfamilyQ5EB52
Human Protein Atlas [tissue]ENSG00000106484-MEST [tissue]
Peptide AtlasQ5EB52
HPRD06776
IPIIPI00298947   IPI00414000   IPI00554507   IPI00926302   IPI00926096   IPI00925599   IPI00925388   IPI00925144   IPI00924907   IPI00924704   
Protein Interaction databases
DIP (DOE-UCLA)Q5EB52
IntAct (EBI)Q5EB52
FunCoupENSG00000106484
BioGRIDMEST
STRING (EMBL)MEST
ZODIACMEST
Ontologies - Pathways
QuickGOQ5EB52
Ontology : AmiGOendoplasmic reticulum  endoplasmic reticulum membrane  mesoderm development  integral component of membrane  hydrolase activity  extracellular exosome  
Ontology : EGO-EBIendoplasmic reticulum  endoplasmic reticulum membrane  mesoderm development  integral component of membrane  hydrolase activity  extracellular exosome  
NDEx NetworkMEST
Atlas of Cancer Signalling NetworkMEST
Wikipedia pathwaysMEST
Orthology - Evolution
OrthoDB4232
GeneTree (enSembl)ENSG00000106484
Phylogenetic Trees/Animal Genes : TreeFamMEST
HOVERGENQ5EB52
HOGENOMQ5EB52
Homologs : HomoloGeneMEST
Homology/Alignments : Family Browser (UCSC)MEST
Gene fusions - Rearrangements
Fusion: Tumor Portal MEST
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMEST [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MEST
dbVarMEST
ClinVarMEST
1000_GenomesMEST 
Exome Variant ServerMEST
ExAC (Exome Aggregation Consortium)ENSG00000106484
GNOMAD BrowserENSG00000106484
Genetic variants : HAPMAP4232
Genomic Variants (DGV)MEST [DGVbeta]
DECIPHERMEST [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMEST 
Mutations
ICGC Data PortalMEST 
TCGA Data PortalMEST 
Broad Tumor PortalMEST
OASIS PortalMEST [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMEST  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMEST
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MEST
DgiDB (Drug Gene Interaction Database)MEST
DoCM (Curated mutations)MEST (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MEST (select a term)
intoGenMEST
Cancer3DMEST(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601029   
Orphanet
MedgenMEST
Genetic Testing Registry MEST
NextProtQ5EB52 [Medical]
TSGene4232
GENETestsMEST
Target ValidationMEST
Huge Navigator MEST [HugePedia]
snp3D : Map Gene to Disease4232
BioCentury BCIQMEST
ClinGenMEST (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4232
Chemical/Pharm GKB GenePA30762
Clinical trialMEST
Miscellaneous
canSAR (ICR)MEST (select the gene name)
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMEST
EVEXMEST
GoPubMedMEST
iHOPMEST
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:58:34 CET 2017

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