MEST (mesoderm specific transcript)

2003-02-01  

Identity

HGNC
MEST
LOCATION
7q32.2
LOCUSID
4232
ALIAS
PEG1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4232
MIM: 601029
HGNC: 7028
Ensembl: ENSG00000106484

Variants:

dbSNP: 4232
ClinVar: 4232
TCGA: ENSG00000106484
COSMIC: MEST

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106484ENST00000223215Q5EB52
ENSG00000106484ENST00000223215A0A024R768
ENSG00000106484ENST00000341441Q5EB52
ENSG00000106484ENST00000341441A4D1L9
ENSG00000106484ENST00000378576Q5EB52
ENSG00000106484ENST00000393187Q5EB52
ENSG00000106484ENST00000393187A4D1L9
ENSG00000106484ENST00000399874C9JG66
ENSG00000106484ENST00000416162Q5EB52
ENSG00000106484ENST00000421001C9JWU9
ENSG00000106484ENST00000427521Q5EB52
ENSG00000106484ENST00000433159C9JRA9
ENSG00000106484ENST00000437637C9JUD2
ENSG00000106484ENST00000437945C9JW74
ENSG00000106484ENST00000458161C9JCM6
ENSG00000106484ENST00000462132Q5EB52
ENSG00000106484ENST00000462132A4D1L9
ENSG00000106484ENST00000463263R4GN52

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
222492492012Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling.86
232091872013Metabolic programming of MEST DNA methylation by intrauterine exposure to gestational diabetes mellitus.66
186448382008Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance.37
233437542013Placentas from pregnancies conceived by IVF/ICSI have a reduced DNA methylation level at the H19 and MEST differentially methylated regions.34
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.32
206286242010Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".29
232297282013Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma.27
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.25
174504332007Silver-Russell syndrome in a girl born after in vitro fertilization: partial hypermethylation at the differentially methylated region of PEG1/MEST.24
91928431997Monoallelic expression of human PEG1/MEST is paralleled by parent-specific methylation in fetuses.23

Citation

Dessen P

MEST (mesoderm specific transcript)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41340/mest