METRNL (meteorin like, glial cell differentiation regulator)

2018-07-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 284207
MIM: 616241
HGNC: 27584
Ensembl: ENSG00000176845

Variants:

dbSNP: 284207
ClinVar: 284207
TCGA: ENSG00000176845
COSMIC: METRNL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176845ENST00000320095Q641Q3
ENSG00000176845ENST00000570778Q641Q3
ENSG00000176845ENST00000571814Q641Q3
ENSG00000176845ENST00000574053I3L0R0

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
243932922014Subfatin is a novel adipokine and unlike Meteorin in adipose and brain expression.0
263075852015Adipocyte Metrnl Antagonizes Insulin Resistance Through PPARγ Signaling.0
277168262016Meteorin-Like Shows Unique Expression Pattern in Bone and Its Overexpression Inhibits Osteoblast Differentiation.0
277487452017METRNL decreases during adipogenesis and inhibits adipocyte differentiation leading to adipocyte hypertrophy in humans.0
302125812018Lower serum levels of Meteorin-like/Subfatin in patients with coronary artery disease and type 2 diabetes mellitus are negatively associated with insulin resistance and inflammatory cytokines.0
303946662019Serum Metrnl is associated with the presence and severity of coronary artery disease.0
308255622019Association of low serum Meteorin like (Metrnl) concentrations with worsening of glucose tolerance, impaired endothelial function and atherosclerosis.0

Citation

Dessen P

METRNL (meteorin like, glial cell differentiation regulator)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57591/metrnl