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METTL16 (methyltransferase like 16)

Identity

Alias_namesMETT10D
methyltransferase 10 domain containing
Alias_symbol (synonym)MGC3329
Other alias
HGNC (Hugo) METTL16
LocusID (NCBI) 79066
Atlas_Id 47510
Location 17p13.3  [Link to chromosome band 17p13]
Location_base_pair Starts at 2416054 and ends at 2511906 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
H6PD (1p36.22) / METTL16 (17p13.3)METTL16 (17p13.3) / METTL16 (17p13.3)METTL16 (17p13.3) / TXNDC17 (17p13.1)
PTPRF (1p34.2) / METTL16 (17p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)METTL16   28484
Cards
Entrez_Gene (NCBI)METTL16  79066  methyltransferase like 16
AliasesMETT10D
GeneCards (Weizmann)METTL16
Ensembl hg19 (Hinxton)ENSG00000127804 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000127804 [Gene_View]  chr17:2416054-2511906 [Contig_View]  METTL16 [Vega]
ICGC DataPortalENSG00000127804
TCGA cBioPortalMETTL16
AceView (NCBI)METTL16
Genatlas (Paris)METTL16
WikiGenes79066
SOURCE (Princeton)METTL16
Genetics Home Reference (NIH)METTL16
Genomic and cartography
GoldenPath hg38 (UCSC)METTL16  -     chr17:2416054-2511906 -  17p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)METTL16  -     17p13.3   [Description]    (hg19-Feb_2009)
EnsemblMETTL16 - 17p13.3 [CytoView hg19]  METTL16 - 17p13.3 [CytoView hg38]
Mapping of homologs : NCBIMETTL16 [Mapview hg19]  METTL16 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK027410 AK098286 AK294547 AK296464 AL832612
RefSeq transcript (Entrez)NM_024086
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)METTL16
Cluster EST : UnigeneHs.632237 [ NCBI ]
CGAP (NCI)Hs.632237
Alternative Splicing GalleryENSG00000127804
Gene ExpressionMETTL16 [ NCBI-GEO ]   METTL16 [ EBI - ARRAY_EXPRESS ]   METTL16 [ SEEK ]   METTL16 [ MEM ]
Gene Expression Viewer (FireBrowse)METTL16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79066
GTEX Portal (Tissue expression)METTL16
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86W50   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86W50  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86W50
Splice isoforms : SwissVarQ86W50
Catalytic activity : Enzyme2.1.1.- [ Enzyme-Expasy ]   2.1.1.-2.1.1.- [ IntEnz-EBI ]   2.1.1.- [ BRENDA ]   2.1.1.- [ KEGG ]   
PhosPhoSitePlusQ86W50
Domains : Interpro (EBI)rRNA_lsu_MeTfrase_F-like    S-AdoMet-dep_MeTrfase_Mett10D    SAM-dependent_MTases   
Domain families : Pfam (Sanger)Methyltransf_10 (PF05971)   
Domain families : Pfam (NCBI)pfam05971   
Conserved Domain (NCBI)METTL16
DMDM Disease mutations79066
Blocks (Seattle)METTL16
PDB (SRS)2H00   
PDB (PDBSum)2H00   
PDB (IMB)2H00   
PDB (RSDB)2H00   
Structural Biology KnowledgeBase2H00   
SCOP (Structural Classification of Proteins)2H00   
CATH (Classification of proteins structures)2H00   
SuperfamilyQ86W50
Human Protein AtlasENSG00000127804
Peptide AtlasQ86W50
HPRD14556
IPIIPI00163391   IPI00792378   IPI01009560   IPI01018183   IPI00921997   
Protein Interaction databases
DIP (DOE-UCLA)Q86W50
IntAct (EBI)Q86W50
FunCoupENSG00000127804
BioGRIDMETTL16
STRING (EMBL)METTL16
ZODIACMETTL16
Ontologies - Pathways
QuickGOQ86W50
Ontology : AmiGORNA binding  nucleus  23S rRNA (adenine(1618)-N(6))-methyltransferase activity  rRNA base methylation  
Ontology : EGO-EBIRNA binding  nucleus  23S rRNA (adenine(1618)-N(6))-methyltransferase activity  rRNA base methylation  
NDEx NetworkMETTL16
Atlas of Cancer Signalling NetworkMETTL16
Wikipedia pathwaysMETTL16
Orthology - Evolution
OrthoDB79066
GeneTree (enSembl)ENSG00000127804
Phylogenetic Trees/Animal Genes : TreeFamMETTL16
HOVERGENQ86W50
HOGENOMQ86W50
Homologs : HomoloGeneMETTL16
Homology/Alignments : Family Browser (UCSC)METTL16
Gene fusions - Rearrangements
Fusion : MitelmanPTPRF/METTL16 [1p34.2/17p13.3]  [t(1;17)(p34;p13)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMETTL16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)METTL16
dbVarMETTL16
ClinVarMETTL16
1000_GenomesMETTL16 
Exome Variant ServerMETTL16
ExAC (Exome Aggregation Consortium)METTL16 (select the gene name)
Genetic variants : HAPMAP79066
Genomic Variants (DGV)METTL16 [DGVbeta]
DECIPHERMETTL16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMETTL16 
Mutations
ICGC Data PortalMETTL16 
TCGA Data PortalMETTL16 
Broad Tumor PortalMETTL16
OASIS PortalMETTL16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMETTL16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMETTL16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch METTL16
DgiDB (Drug Gene Interaction Database)METTL16
DoCM (Curated mutations)METTL16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)METTL16 (select a term)
intoGenMETTL16
Cancer3DMETTL16(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenMETTL16
Genetic Testing Registry METTL16
NextProtQ86W50 [Medical]
TSGene79066
GENETestsMETTL16
Target ValidationMETTL16
Huge Navigator METTL16 [HugePedia]
snp3D : Map Gene to Disease79066
BioCentury BCIQMETTL16
ClinGenMETTL16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79066
Chemical/Pharm GKB GenePA142671460
Clinical trialMETTL16
Miscellaneous
canSAR (ICR)METTL16 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMETTL16
EVEXMETTL16
GoPubMedMETTL16
iHOPMETTL16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:17:48 CEST 2017

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