METTL16 (methyltransferase 16, N6-methyladenosine)

2007-04-01  

Identity

HGNC
LOCATION
17p13.3
LOCUSID
ALIAS
METT10D
FUSION GENES

Other Information

Locus ID:

NCBI: 79066
HGNC: 28484
Ensembl: ENSG00000127804

Variants:

dbSNP: 79066
ClinVar: 79066
TCGA: ENSG00000127804
COSMIC: METTL16

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127804ENST00000263092Q86W50
ENSG00000127804ENST00000571298K7EKQ8
ENSG00000127804ENST00000574752I3L362
ENSG00000127804ENST00000576556I3L3W3
ENSG00000127804ENST00000576976I3L4V1

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
285257532017The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.119
290512002017Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs.80
278723112016Methyltransferase-like protein 16 binds the 3'-terminal triple helix of MALAT1 long noncoding RNA.38
292623162017S-Adenosylmethionine Synthesis Is Regulated by Selective N6-Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC1.38
295932912018Structural insights into the RNA methyltransferase domain of METTL16.17
206027512010Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.6
316657432019METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis.5
319404102020Characterization of METTL16 as a cytoplasmic RNA binding protein.1

Citation

Dessen P

METTL16 (methyltransferase 16, N6-methyladenosine)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47510/mettl16