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METTL24 (methyltransferase like 24)

Identity

Alias_namesC6orf186
chromosome 6 open reading frame 186
Alias_symbol (synonym)dJ71D21.2
Other alias
HGNC (Hugo) METTL24
LocusID (NCBI) 728464
Atlas_Id 68920
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 110245946 and ends at 110358272 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CDC40 (6q21) / METTL24 (6q21)GMDS (6p25.3) / METTL24 (6q21)METTL24 (6q21) / METTL24 (6q21)
METTL24 (6q21) / SLC22A16 (6q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p25;q21) GMDS/METTL24


External links

Nomenclature
HGNC (Hugo)METTL24   21566
Cards
Entrez_Gene (NCBI)METTL24  728464  methyltransferase like 24
AliasesC6orf186; dJ71D21.2
GeneCards (Weizmann)METTL24
Ensembl hg19 (Hinxton)ENSG00000053328 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000053328 [Gene_View]  ENSG00000053328 [Sequence]  chr6:110245946-110358272 [Contig_View]  METTL24 [Vega]
ICGC DataPortalENSG00000053328
TCGA cBioPortalMETTL24
AceView (NCBI)METTL24
Genatlas (Paris)METTL24
WikiGenes728464
SOURCE (Princeton)METTL24
Genetics Home Reference (NIH)METTL24
Genomic and cartography
GoldenPath hg38 (UCSC)METTL24  -     chr6:110245946-110358272 -  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)METTL24  -     6q21   [Description]    (hg19-Feb_2009)
EnsemblMETTL24 - 6q21 [CytoView hg19]  METTL24 - 6q21 [CytoView hg38]
Mapping of homologs : NCBIMETTL24 [Mapview hg19]  METTL24 [Mapview hg38]
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001123364
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)METTL24
Cluster EST : UnigeneHs.722171 [ NCBI ]
CGAP (NCI)Hs.722171
Alternative Splicing GalleryENSG00000053328
Gene ExpressionMETTL24 [ NCBI-GEO ]   METTL24 [ EBI - ARRAY_EXPRESS ]   METTL24 [ SEEK ]   METTL24 [ MEM ]
Gene Expression Viewer (FireBrowse)METTL24 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)728464
GTEX Portal (Tissue expression)METTL24
Human Protein AtlasENSG00000053328-METTL24 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JXM2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JXM2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JXM2
Splice isoforms : SwissVarQ5JXM2
Catalytic activity : Enzyme2.1.1.- [ Enzyme-Expasy ]   2.1.1.-2.1.1.- [ IntEnz-EBI ]   2.1.1.- [ BRENDA ]   2.1.1.- [ KEGG ]   
PhosPhoSitePlusQ5JXM2
Domains : Interpro (EBI)Methyltranfer_dom    METTL24   
Domain families : Pfam (Sanger)Methyltransf_22 (PF13383)   
Domain families : Pfam (NCBI)pfam13383   
Conserved Domain (NCBI)METTL24
DMDM Disease mutations728464
Blocks (Seattle)METTL24
SuperfamilyQ5JXM2
Human Protein Atlas [tissue]ENSG00000053328-METTL24 [tissue]
Peptide AtlasQ5JXM2
IPIIPI00641651   
Protein Interaction databases
DIP (DOE-UCLA)Q5JXM2
IntAct (EBI)Q5JXM2
FunCoupENSG00000053328
BioGRIDMETTL24
STRING (EMBL)METTL24
ZODIACMETTL24
Ontologies - Pathways
QuickGOQ5JXM2
Ontology : AmiGOextracellular region  methyltransferase activity  methylation  
Ontology : EGO-EBIextracellular region  methyltransferase activity  methylation  
NDEx NetworkMETTL24
Atlas of Cancer Signalling NetworkMETTL24
Wikipedia pathwaysMETTL24
Orthology - Evolution
OrthoDB728464
GeneTree (enSembl)ENSG00000053328
Phylogenetic Trees/Animal Genes : TreeFamMETTL24
HOVERGENQ5JXM2
HOGENOMQ5JXM2
Homologs : HomoloGeneMETTL24
Homology/Alignments : Family Browser (UCSC)METTL24
Gene fusions - Rearrangements
Fusion : QuiverMETTL24
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMETTL24 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)METTL24
dbVarMETTL24
ClinVarMETTL24
1000_GenomesMETTL24 
Exome Variant ServerMETTL24
ExAC (Exome Aggregation Consortium)ENSG00000053328
GNOMAD BrowserENSG00000053328
Varsome BrowserMETTL24
Genetic variants : HAPMAP728464
Genomic Variants (DGV)METTL24 [DGVbeta]
DECIPHERMETTL24 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMETTL24 
Mutations
ICGC Data PortalMETTL24 
TCGA Data PortalMETTL24 
Broad Tumor PortalMETTL24
OASIS PortalMETTL24 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMETTL24
BioMutasearch METTL24
DgiDB (Drug Gene Interaction Database)METTL24
DoCM (Curated mutations)METTL24 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)METTL24 (select a term)
intoGenMETTL24
Cancer3DMETTL24(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETMETTL24
MedgenMETTL24
Genetic Testing Registry METTL24
NextProtQ5JXM2 [Medical]
TSGene728464
GENETestsMETTL24
Target ValidationMETTL24
Huge Navigator METTL24 [HugePedia]
snp3D : Map Gene to Disease728464
BioCentury BCIQMETTL24
ClinGenMETTL24
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD728464
Chemical/Pharm GKB GenePA134906793
Clinical trialMETTL24
Miscellaneous
canSAR (ICR)METTL24 (select the gene name)
Probes
Litterature
GeneRIFsGene References Into Functions (Entrez)
CoreMineMETTL24
EVEXMETTL24
GoPubMedMETTL24
iHOPMETTL24
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Jul 30 14:12:42 CEST 2018

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