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METTL25 (methyltransferase like 25)

Identity

Alias (NCBI)C12orf26
HGNC (Hugo) METTL25
HGNC Alias symbFLJ22789
HGNC Previous nameC12orf26
HGNC Previous namechromosome 12 open reading frame 26
LocusID (NCBI) 84190
Atlas_Id 68921
Location 12q21.31  [Link to chromosome band 12q21]
Location_base_pair Starts at 82358497 and ends at 82479237 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ABHD12 (20p11.21) / METTL25 (12q21.31)LRTOMT (11q13.4) / METTL25 (12q21.31)METTL25 (12q21.31) / AMDHD1 (12q23.1)
METTL25 (12q21.31) / FGD6 (12q22)SYT1 (12q21.2) / METTL25 (12q21.31)TBC1D15 (12q21.1) / METTL25 (12q21.31)
TMTC2 (12q21.31) / METTL25 (12q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 6 ]
  t(11;12)(q13;q21) LRTOMT/METTL25
SYT1/METTL25 (12q21)
TBC1D15/METTL25 (12q21)
TMTC2/METTL25 (12q21)
t(12;12)(q21;q22) METTL25/FGD6
t(12;12)(q21;q23) METTL25/AMDHD1


External links

Nomenclature
HGNC (Hugo)METTL25   26228
Cards
Entrez_Gene (NCBI)METTL25  84190  methyltransferase like 25
AliasesC12orf26
GeneCards (Weizmann)METTL25
Ensembl hg19 (Hinxton)ENSG00000127720 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000127720 [Gene_View]  ENSG00000127720 [Sequence]  chr12:82358497-82479237 [Contig_View]  METTL25 [Vega]
ICGC DataPortalENSG00000127720
TCGA cBioPortalMETTL25
AceView (NCBI)METTL25
Genatlas (Paris)METTL25
WikiGenes84190
SOURCE (Princeton)METTL25
Genetics Home Reference (NIH)METTL25
Genomic and cartography
GoldenPath hg38 (UCSC)METTL25  -     chr12:82358497-82479237 +  12q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)METTL25  -     12q21.31   [Description]    (hg19-Feb_2009)
GoldenPathMETTL25 - 12q21.31 [CytoView hg19]  METTL25 - 12q21.31 [CytoView hg38]
ImmunoBaseENSG00000127720
genome Data Viewer NCBIMETTL25 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK026442 AK310231 BC029120 BG186273 DB059865
RefSeq transcript (Entrez)NM_001319675 NM_001347934 NM_032230
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)METTL25
Alternative Splicing GalleryENSG00000127720
Gene ExpressionMETTL25 [ NCBI-GEO ]   METTL25 [ EBI - ARRAY_EXPRESS ]   METTL25 [ SEEK ]   METTL25 [ MEM ]
Gene Expression Viewer (FireBrowse)METTL25 [ Firebrowse - Broad ]
GenevisibleExpression of METTL25 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84190
GTEX Portal (Tissue expression)METTL25
Human Protein AtlasENSG00000127720-METTL25 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N6Q8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N6Q8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N6Q8
Splice isoforms : SwissVarQ8N6Q8
PhosPhoSitePlusQ8N6Q8
Domains : Interpro (EBI)Methyltranfer_dom    SAM-dependent_MTases   
Domain families : Pfam (Sanger)Methyltransf_32 (PF13679)   
Domain families : Pfam (NCBI)pfam13679   
Conserved Domain (NCBI)METTL25
DMDM Disease mutations84190
Blocks (Seattle)METTL25
SuperfamilyQ8N6Q8
Human Protein Atlas [tissue]ENSG00000127720-METTL25 [tissue]
Peptide AtlasQ8N6Q8
HPRD10979
IPIIPI00297450   IPI01022228   IPI01022420   IPI01022054   
Protein Interaction databases
DIP (DOE-UCLA)Q8N6Q8
IntAct (EBI)Q8N6Q8
FunCoupENSG00000127720
BioGRIDMETTL25
STRING (EMBL)METTL25
ZODIACMETTL25
Ontologies - Pathways
QuickGOQ8N6Q8
Ontology : AmiGOmethyltransferase activity  methylation  
Ontology : EGO-EBImethyltransferase activity  methylation  
NDEx NetworkMETTL25
Atlas of Cancer Signalling NetworkMETTL25
Wikipedia pathwaysMETTL25
Orthology - Evolution
OrthoDB84190
GeneTree (enSembl)ENSG00000127720
Phylogenetic Trees/Animal Genes : TreeFamMETTL25
HOGENOMQ8N6Q8
Homologs : HomoloGeneMETTL25
Homology/Alignments : Family Browser (UCSC)METTL25
Gene fusions - Rearrangements
Fusion : QuiverMETTL25
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMETTL25 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)METTL25
dbVarMETTL25
ClinVarMETTL25
1000_GenomesMETTL25 
Exome Variant ServerMETTL25
GNOMAD BrowserENSG00000127720
Varsome BrowserMETTL25
Genetic variants : HAPMAP84190
Genomic Variants (DGV)METTL25 [DGVbeta]
DECIPHERMETTL25 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMETTL25 
Mutations
ICGC Data PortalMETTL25 
TCGA Data PortalMETTL25 
Broad Tumor PortalMETTL25
OASIS PortalMETTL25 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMETTL25  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMETTL25
Mutations and Diseases : HGMDMETTL25
BioMutasearch METTL25
DgiDB (Drug Gene Interaction Database)METTL25
DoCM (Curated mutations)METTL25 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)METTL25 (select a term)
intoGenMETTL25
Cancer3DMETTL25(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETMETTL25
MedgenMETTL25
Genetic Testing Registry METTL25
NextProtQ8N6Q8 [Medical]
TSGene84190
GENETestsMETTL25
Target ValidationMETTL25
Huge Navigator METTL25 [HugePedia]
snp3D : Map Gene to Disease84190
BioCentury BCIQMETTL25
ClinGenMETTL25
Clinical trials, drugs, therapy
Protein Interactions : CTD84190
Pharm GKB GenePA142672297
Clinical trialMETTL25
Miscellaneous
canSAR (ICR)METTL25 (select the gene name)
HarmonizomeMETTL25
DataMed IndexMETTL25
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMETTL25
EVEXMETTL25
GoPubMedMETTL25
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jul 16 16:13:36 CEST 2020

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