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METTL2A (methyltransferase 2A, methylcytidine)

Identity

Alias (NCBI)METTL2
HGNC (Hugo) METTL2A
HGNC Alias symbFLJ12760
METTL2
LocusID (NCBI) 339175
Atlas_Id 68922
Location 17q23.2  [Link to chromosome band 17q23]
Location_base_pair Starts at 62423897 and ends at 62453385 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
METTL2A (17q23.2) / EFCAB3 (17q23.2)METTL2A (17q23.2) / IRGQ (19q13.31)METTL2A (17q23.2) / PNO1 (2p14)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)METTL2A   25755
Cards
Entrez_Gene (NCBI)METTL2A    methyltransferase 2A, methylcytidine
AliasesMETTL2
GeneCards (Weizmann)METTL2A
Ensembl hg19 (Hinxton)ENSG00000087995 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000087995 [Gene_View]  ENSG00000087995 [Sequence]  chr17:62423897-62453385 [Contig_View]  METTL2A [Vega]
ICGC DataPortalENSG00000087995
TCGA cBioPortalMETTL2A
AceView (NCBI)METTL2A
Genatlas (Paris)METTL2A
SOURCE (Princeton)METTL2A
Genetics Home Reference (NIH)METTL2A
Genomic and cartography
GoldenPath hg38 (UCSC)METTL2A  -     chr17:62423897-62453385 +  17q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)METTL2A  -     17q23.2   [Description]    (hg19-Feb_2009)
GoldenPathMETTL2A - 17q23.2 [CytoView hg19]  METTL2A - 17q23.2 [CytoView hg38]
ImmunoBaseENSG00000087995
Genome Data Viewer NCBIMETTL2A [Mapview hg19]  
OMIM618902   
Gene and transcription
Genbank (Entrez)AF161384 AF161385 AK000991 AK022822 BC006985
RefSeq transcript (Entrez)NM_001005372 NM_181725
Consensus coding sequences : CCDS (NCBI)METTL2A
Gene ExpressionMETTL2A [ NCBI-GEO ]   METTL2A [ EBI - ARRAY_EXPRESS ]   METTL2A [ SEEK ]   METTL2A [ MEM ]
Gene Expression Viewer (FireBrowse)METTL2A [ Firebrowse - Broad ]
GenevisibleExpression of METTL2A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339175
GTEX Portal (Tissue expression)METTL2A
Human Protein AtlasENSG00000087995-METTL2A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96IZ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96IZ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96IZ6
PhosPhoSitePlusQ96IZ6
Domains : Interpro (EBI)MeTrfase    SAM-dependent_MTases   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)METTL2A
SuperfamilyQ96IZ6
AlphaFold pdb e-kbQ96IZ6   
Human Protein Atlas [tissue]ENSG00000087995-METTL2A [tissue]
HPRD07795
Protein Interaction databases
DIP (DOE-UCLA)Q96IZ6
IntAct (EBI)Q96IZ6
BioGRIDMETTL2A
STRING (EMBL)METTL2A
ZODIACMETTL2A
Ontologies - Pathways
QuickGOQ96IZ6
Ontology : AmiGOprotein binding  tRNA (cytosine) methyltransferase activity  tRNA methylation  tRNA methylation  tRNA (cytosine-3-)-methyltransferase activity  tRNA (cytosine-3-)-methyltransferase activity  
Ontology : EGO-EBIprotein binding  tRNA (cytosine) methyltransferase activity  tRNA methylation  tRNA methylation  tRNA (cytosine-3-)-methyltransferase activity  tRNA (cytosine-3-)-methyltransferase activity  
NDEx NetworkMETTL2A
Atlas of Cancer Signalling NetworkMETTL2A
Wikipedia pathwaysMETTL2A
Orthology - Evolution
OrthoDB339175
GeneTree (enSembl)ENSG00000087995
Phylogenetic Trees/Animal Genes : TreeFamMETTL2A
Homologs : HomoloGeneMETTL2A
Homology/Alignments : Family Browser (UCSC)METTL2A
Gene fusions - Rearrangements
Fusion : QuiverMETTL2A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMETTL2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)METTL2A
dbVarMETTL2A
ClinVarMETTL2A
MonarchMETTL2A
1000_GenomesMETTL2A 
Exome Variant ServerMETTL2A
GNOMAD BrowserENSG00000087995
Varsome BrowserMETTL2A
ACMGMETTL2A variants
VarityQ96IZ6
Genomic Variants (DGV)METTL2A [DGVbeta]
DECIPHERMETTL2A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMETTL2A 
Mutations
ICGC Data PortalMETTL2A 
TCGA Data PortalMETTL2A 
Broad Tumor PortalMETTL2A
OASIS PortalMETTL2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMETTL2A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMETTL2A
Mutations and Diseases : HGMDMETTL2A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMETTL2A
DgiDB (Drug Gene Interaction Database)METTL2A
DoCM (Curated mutations)METTL2A
CIViC (Clinical Interpretations of Variants in Cancer)METTL2A
Cancer3DMETTL2A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618902   
Orphanet
DisGeNETMETTL2A
MedgenMETTL2A
Genetic Testing Registry METTL2A
NextProtQ96IZ6 [Medical]
GENETestsMETTL2A
Target ValidationMETTL2A
Huge Navigator METTL2A [HugePedia]
ClinGenMETTL2A
Clinical trials, drugs, therapy
MyCancerGenomeMETTL2A
Protein Interactions : CTDMETTL2A
Pharm GKB GenePA143485532
PharosQ96IZ6
Clinical trialMETTL2A
Miscellaneous
canSAR (ICR)METTL2A
HarmonizomeMETTL2A
DataMed IndexMETTL2A
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMETTL2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:07:11 CEST 2021

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