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METTL2B (methyltransferase 2B, methylcytidine)

Identity

Alias (NCBI)METL
METTL2
METTL2A
PSENIP1
HGNC (Hugo) METTL2B
HGNC Alias symbMETL
FLJ11350
HGNC Previous nameMETTL2
HGNC Previous namemethyltransferase like 2
LocusID (NCBI) 55798
Atlas_Id 68923
Location 7q32.1  [Link to chromosome band 7q32]
Location_base_pair Starts at 128476748 and ends at 128506602 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ELN (7q11.23) / METTL2B (7q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)METTL2B   18272
Cards
Entrez_Gene (NCBI)METTL2B    methyltransferase 2B, methylcytidine
AliasesMETL; METTL2; METTL2A; PSENIP1
GeneCards (Weizmann)METTL2B
Ensembl hg19 (Hinxton)ENSG00000165055 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165055 [Gene_View]  ENSG00000165055 [Sequence]  chr7:128476748-128506602 [Contig_View]  METTL2B [Vega]
ICGC DataPortalENSG00000165055
TCGA cBioPortalMETTL2B
AceView (NCBI)METTL2B
Genatlas (Paris)METTL2B
SOURCE (Princeton)METTL2B
Genetics Home Reference (NIH)METTL2B
Genomic and cartography
GoldenPath hg38 (UCSC)METTL2B  -     chr7:128476748-128506602 +  7q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)METTL2B  -     7q32.1   [Description]    (hg19-Feb_2009)
GoldenPathMETTL2B - 7q32.1 [CytoView hg19]  METTL2B - 7q32.1 [CytoView hg38]
ImmunoBaseENSG00000165055
Genome Data Viewer NCBIMETTL2B [Mapview hg19]  
OMIM607846   
Gene and transcription
Genbank (Entrez)AK002212 AK125539 AK299960 AK302775 AY358237
RefSeq transcript (Entrez)NM_018396
Consensus coding sequences : CCDS (NCBI)METTL2B
Gene ExpressionMETTL2B [ NCBI-GEO ]   METTL2B [ EBI - ARRAY_EXPRESS ]   METTL2B [ SEEK ]   METTL2B [ MEM ]
Gene Expression Viewer (FireBrowse)METTL2B [ Firebrowse - Broad ]
GenevisibleExpression of METTL2B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55798
GTEX Portal (Tissue expression)METTL2B
Human Protein AtlasENSG00000165055-METTL2B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P1Q9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P1Q9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P1Q9
PhosPhoSitePlusQ6P1Q9
Domains : Interpro (EBI)MeTrfase    SAM-dependent_MTases   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)METTL2B
SuperfamilyQ6P1Q9
AlphaFold pdb e-kbQ6P1Q9   
Human Protein Atlas [tissue]ENSG00000165055-METTL2B [tissue]
HPRD09705
Protein Interaction databases
DIP (DOE-UCLA)Q6P1Q9
IntAct (EBI)Q6P1Q9
BioGRIDMETTL2B
STRING (EMBL)METTL2B
ZODIACMETTL2B
Ontologies - Pathways
QuickGOQ6P1Q9
Ontology : AmiGOprotein binding  tRNA (cytosine) methyltransferase activity  tRNA methylation  tRNA (cytosine-3-)-methyltransferase activity  tRNA (cytosine-3-)-methyltransferase activity  
Ontology : EGO-EBIprotein binding  tRNA (cytosine) methyltransferase activity  tRNA methylation  tRNA (cytosine-3-)-methyltransferase activity  tRNA (cytosine-3-)-methyltransferase activity  
Pathways : KEGGSelenoamino acid metabolism    Tyrosine metabolism    Aminophosphonate metabolism    Nitrobenzene degradation    Tryptophan metabolism    Histidine metabolism    Androgen and estrogen metabolism   
NDEx NetworkMETTL2B
Atlas of Cancer Signalling NetworkMETTL2B
Wikipedia pathwaysMETTL2B
Orthology - Evolution
OrthoDB55798
GeneTree (enSembl)ENSG00000165055
Phylogenetic Trees/Animal Genes : TreeFamMETTL2B
Homologs : HomoloGeneMETTL2B
Homology/Alignments : Family Browser (UCSC)METTL2B
Gene fusions - Rearrangements
Fusion : QuiverMETTL2B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMETTL2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)METTL2B
dbVarMETTL2B
ClinVarMETTL2B
MonarchMETTL2B
1000_GenomesMETTL2B 
Exome Variant ServerMETTL2B
GNOMAD BrowserENSG00000165055
Varsome BrowserMETTL2B
ACMGMETTL2B variants
VarityQ6P1Q9
Genomic Variants (DGV)METTL2B [DGVbeta]
DECIPHERMETTL2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMETTL2B 
Mutations
ICGC Data PortalMETTL2B 
TCGA Data PortalMETTL2B 
Broad Tumor PortalMETTL2B
OASIS PortalMETTL2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMETTL2B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMETTL2B
Mutations and Diseases : HGMDMETTL2B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMETTL2B
DgiDB (Drug Gene Interaction Database)METTL2B
DoCM (Curated mutations)METTL2B
CIViC (Clinical Interpretations of Variants in Cancer)METTL2B
Cancer3DMETTL2B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607846   
Orphanet
DisGeNETMETTL2B
MedgenMETTL2B
Genetic Testing Registry METTL2B
NextProtQ6P1Q9 [Medical]
GENETestsMETTL2B
Target ValidationMETTL2B
Huge Navigator METTL2B [HugePedia]
ClinGenMETTL2B
Clinical trials, drugs, therapy
MyCancerGenomeMETTL2B
Protein Interactions : CTDMETTL2B
Pharm GKB GenePA134924546
PharosQ6P1Q9
Clinical trialMETTL2B
Miscellaneous
canSAR (ICR)METTL2B
HarmonizomeMETTL2B
DataMed IndexMETTL2B
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMETTL2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:07:11 CEST 2021

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