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METTL2B (methyltransferase like 2B)

Identity

Alias_namesMETTL2
methyltransferase like 2
Alias_symbol (synonym)METL
FLJ11350
Other aliasMETTL2A
PSENIP1
HGNC (Hugo) METTL2B
LocusID (NCBI) 55798
Atlas_Id 68923
Location 7q32.1  [Link to chromosome band 7q32]
Location_base_pair Starts at 128476729 and ends at 128502924 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ELN (7q11.23) / METTL2B (7q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)METTL2B   18272
Cards
Entrez_Gene (NCBI)METTL2B  55798  methyltransferase like 2B
AliasesMETL; METTL2; METTL2A; PSENIP1
GeneCards (Weizmann)METTL2B
Ensembl hg19 (Hinxton)ENSG00000165055 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165055 [Gene_View]  chr7:128476729-128502924 [Contig_View]  METTL2B [Vega]
ICGC DataPortalENSG00000165055
TCGA cBioPortalMETTL2B
AceView (NCBI)METTL2B
Genatlas (Paris)METTL2B
WikiGenes55798
SOURCE (Princeton)METTL2B
Genetics Home Reference (NIH)METTL2B
Genomic and cartography
GoldenPath hg38 (UCSC)METTL2B  -     chr7:128476729-128502924 +  7q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)METTL2B  -     7q32.1   [Description]    (hg19-Feb_2009)
EnsemblMETTL2B - 7q32.1 [CytoView hg19]  METTL2B - 7q32.1 [CytoView hg38]
Mapping of homologs : NCBIMETTL2B [Mapview hg19]  METTL2B [Mapview hg38]
OMIM607846   
Gene and transcription
Genbank (Entrez)AK002212 AK125539 AK299960 AK302775 AY358237
RefSeq transcript (Entrez)NM_018396
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)METTL2B
Cluster EST : UnigeneHs.433213 [ NCBI ]
CGAP (NCI)Hs.433213
Alternative Splicing GalleryENSG00000165055
Gene ExpressionMETTL2B [ NCBI-GEO ]   METTL2B [ EBI - ARRAY_EXPRESS ]   METTL2B [ SEEK ]   METTL2B [ MEM ]
Gene Expression Viewer (FireBrowse)METTL2B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55798
GTEX Portal (Tissue expression)METTL2B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P1Q9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P1Q9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P1Q9
Splice isoforms : SwissVarQ6P1Q9
PhosPhoSitePlusQ6P1Q9
Domains : Interpro (EBI)MeTrfase    SAM-dependent_MTases   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)METTL2B
DMDM Disease mutations55798
Blocks (Seattle)METTL2B
SuperfamilyQ6P1Q9
Human Protein AtlasENSG00000165055
Peptide AtlasQ6P1Q9
HPRD09705
IPIIPI00853093   IPI00181997   IPI00432690   IPI00853035   IPI00945858   IPI00945686   IPI00946046   
Protein Interaction databases
DIP (DOE-UCLA)Q6P1Q9
IntAct (EBI)Q6P1Q9
FunCoupENSG00000165055
BioGRIDMETTL2B
STRING (EMBL)METTL2B
ZODIACMETTL2B
Ontologies - Pathways
QuickGOQ6P1Q9
Ontology : AmiGOtRNA (cytosine) methyltransferase activity  tRNA methylation  
Ontology : EGO-EBItRNA (cytosine) methyltransferase activity  tRNA methylation  
Pathways : KEGGHistidine metabolism    Tyrosine metabolism   
NDEx NetworkMETTL2B
Atlas of Cancer Signalling NetworkMETTL2B
Wikipedia pathwaysMETTL2B
Orthology - Evolution
OrthoDB55798
GeneTree (enSembl)ENSG00000165055
Phylogenetic Trees/Animal Genes : TreeFamMETTL2B
HOVERGENQ6P1Q9
HOGENOMQ6P1Q9
Homologs : HomoloGeneMETTL2B
Homology/Alignments : Family Browser (UCSC)METTL2B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMETTL2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)METTL2B
dbVarMETTL2B
ClinVarMETTL2B
1000_GenomesMETTL2B 
Exome Variant ServerMETTL2B
ExAC (Exome Aggregation Consortium)METTL2B (select the gene name)
Genetic variants : HAPMAP55798
Genomic Variants (DGV)METTL2B [DGVbeta]
DECIPHERMETTL2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMETTL2B 
Mutations
ICGC Data PortalMETTL2B 
TCGA Data PortalMETTL2B 
Broad Tumor PortalMETTL2B
OASIS PortalMETTL2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMETTL2B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMETTL2B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch METTL2B
DgiDB (Drug Gene Interaction Database)METTL2B
DoCM (Curated mutations)METTL2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)METTL2B (select a term)
intoGenMETTL2B
Cancer3DMETTL2B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607846   
Orphanet
MedgenMETTL2B
Genetic Testing Registry METTL2B
NextProtQ6P1Q9 [Medical]
TSGene55798
GENETestsMETTL2B
Target ValidationMETTL2B
Huge Navigator METTL2B [HugePedia]
snp3D : Map Gene to Disease55798
BioCentury BCIQMETTL2B
ClinGenMETTL2B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55798
Chemical/Pharm GKB GenePA134924546
Clinical trialMETTL2B
Miscellaneous
canSAR (ICR)METTL2B (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMETTL2B
EVEXMETTL2B
GoPubMedMETTL2B
iHOPMETTL2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:27:14 CEST 2017

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