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METTL4 (methyltransferase like 4)

Identity

Other namesHsT661
HGNC (Hugo) METTL4
LocusID (NCBI) 64863
Atlas_Id 47028
Location 18p11.32
Location_base_pair Starts at 2537524 and ends at 2571489 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)METTL4   24726
Cards
Entrez_Gene (NCBI)METTL4  64863  methyltransferase like 4
GeneCards (Weizmann)METTL4
Ensembl hg19 (Hinxton)ENSG00000101574 [Gene_View]  chr18:2537524-2571489 [Contig_View]  METTL4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000101574 [Gene_View]  chr18:2537524-2571489 [Contig_View]  METTL4 [Vega]
ICGC DataPortalENSG00000101574
TCGA cBioPortalMETTL4
AceView (NCBI)METTL4
Genatlas (Paris)METTL4
WikiGenes64863
SOURCE (Princeton)METTL4
Genomic and cartography
GoldenPath hg19 (UCSC)METTL4  -     chr18:2537524-2571489 -  18p11.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)METTL4  -     18p11.32   [Description]    (hg38-Dec_2013)
EnsemblMETTL4 - 18p11.32 [CytoView hg19]  METTL4 - 18p11.32 [CytoView hg38]
Mapping of homologs : NCBIMETTL4 [Mapview hg19]  METTL4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK022584 AK026670 AK290001 AL834296 BC056270
RefSeq transcript (Entrez)NM_022840
RefSeq genomic (Entrez)NC_000018 NC_018929 NT_010859 NW_004929409
Consensus coding sequences : CCDS (NCBI)METTL4
Cluster EST : UnigeneHs.126888 [ NCBI ]
CGAP (NCI)Hs.126888
Alternative Splicing : Fast-db (Paris)GSHG0014159
Alternative Splicing GalleryENSG00000101574
Gene ExpressionMETTL4 [ NCBI-GEO ]     METTL4 [ SEEK ]   METTL4 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N3J2 (Uniprot)
NextProtQ8N3J2  [Medical]
With graphics : InterProQ8N3J2
Splice isoforms : SwissVarQ8N3J2 (Swissvar)
Domaine pattern : Prosite (Expaxy)MT_A70 (PS51143)    N6_MTASE (PS00092)   
Domains : Interpro (EBI)DNA_methylase_N6_adenine_CS    MT-A70-like    SAM-dependent_MTases   
Related proteins : CluSTrQ8N3J2
Domain families : Pfam (Sanger)MT-A70 (PF05063)   
Domain families : Pfam (NCBI)pfam05063   
DMDM Disease mutations64863
Blocks (Seattle)Q8N3J2
Human Protein AtlasENSG00000101574
Peptide AtlasQ8N3J2
HPRD14390
IPIIPI00394998   
Protein Interaction databases
DIP (DOE-UCLA)Q8N3J2
IntAct (EBI)Q8N3J2
FunCoupENSG00000101574
BioGRIDMETTL4
IntegromeDBMETTL4
STRING (EMBL)METTL4
Ontologies - Pathways
QuickGOQ8N3J2
Ontology : AmiGOnucleic acid binding  nucleobase-containing compound metabolic process  methyltransferase activity  methylation  
Ontology : EGO-EBInucleic acid binding  nucleobase-containing compound metabolic process  methyltransferase activity  methylation  
Protein Interaction DatabaseMETTL4
DoCM (Curated mutations)METTL4
Wikipedia pathwaysMETTL4
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerMETTL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)METTL4
dbVarMETTL4
ClinVarMETTL4
1000_GenomesMETTL4 
Exome Variant ServerMETTL4
SNP (GeneSNP Utah)METTL4
SNP : HGBaseMETTL4
Genetic variants : HAPMAPMETTL4
Genomic Variants (DGV)METTL4 [DGVbeta]
Mutations
ICGC Data PortalMETTL4 
TCGA Data PortalMETTL4 
Tumor PortalMETTL4
Somatic Mutations in Cancer : COSMICMETTL4 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)18:2537524-2571489
CONAN: Copy Number AnalysisMETTL4 
Mutations and Diseases : HGMDMETTL4
OMIM
MedgenMETTL4
NextProtQ8N3J2 [Medical]
GENETestsMETTL4
Disease Genetic AssociationMETTL4
Huge Navigator METTL4 [HugePedia]  METTL4 [HugeCancerGEM]
snp3D : Map Gene to Disease64863
DGIdb (Drug Gene Interaction db)METTL4
General knowledge
Homologs : HomoloGeneMETTL4
Homology/Alignments : Family Browser (UCSC)METTL4
Phylogenetic Trees/Animal Genes : TreeFamMETTL4
Chemical/Protein Interactions : CTD64863
Chemical/Pharm GKB GenePA134916468
Clinical trialMETTL4
Cancer Resource (Charite)ENSG00000101574
Other databases
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
CoreMineMETTL4
GoPubMedMETTL4
iHOPMETTL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 20 19:37:59 CEST 2015

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