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METTL6 (methyltransferase like 6)

Identity

Alias_symbol (synonym)MGC24132
Other alias-
HGNC (Hugo) METTL6
LocusID (NCBI) 131965
Atlas_Id 68926
Location 3p25.1  [Link to chromosome band 3p25]
Location_base_pair Starts at 15451267 and ends at 15469054 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SH3BP5 (3p25.1) / METTL6 (3p25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)METTL6   28343
Cards
Entrez_Gene (NCBI)METTL6  131965  methyltransferase like 6
Aliases
GeneCards (Weizmann)METTL6
Ensembl hg19 (Hinxton)ENSG00000206562 [Gene_View]  chr3:15451267-15469054 [Contig_View]  METTL6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000206562 [Gene_View]  chr3:15451267-15469054 [Contig_View]  METTL6 [Vega]
ICGC DataPortalENSG00000206562
TCGA cBioPortalMETTL6
AceView (NCBI)METTL6
Genatlas (Paris)METTL6
WikiGenes131965
SOURCE (Princeton)METTL6
Genetics Home Reference (NIH)METTL6
Genomic and cartography
GoldenPath hg19 (UCSC)METTL6  -     chr3:15451267-15469054 -  3p25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)METTL6  -     3p25.1   [Description]    (hg38-Dec_2013)
EnsemblMETTL6 - 3p25.1 [CytoView hg19]  METTL6 - 3p25.1 [CytoView hg38]
Mapping of homologs : NCBIMETTL6 [Mapview hg19]  METTL6 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK027185 AK057791 AK293370 BC022400 BC036687
RefSeq transcript (Entrez)NM_001301790 NM_001301791 NM_001301792 NM_152396
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)METTL6
Cluster EST : UnigeneHs.149487 [ NCBI ]
CGAP (NCI)Hs.149487
Alternative Splicing GalleryENSG00000206562
Gene ExpressionMETTL6 [ NCBI-GEO ]   METTL6 [ EBI - ARRAY_EXPRESS ]   METTL6 [ SEEK ]   METTL6 [ MEM ]
Gene Expression Viewer (FireBrowse)METTL6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)131965
GTEX Portal (Tissue expression)METTL6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TCB7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TCB7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TCB7
Splice isoforms : SwissVarQ8TCB7
PhosPhoSitePlusQ8TCB7
Domains : Interpro (EBI)Methyltransf_12    MeTrfase    SAM-dependent_MTases   
Domain families : Pfam (Sanger)Methyltransf_12 (PF08242)   
Domain families : Pfam (NCBI)pfam08242   
Conserved Domain (NCBI)METTL6
DMDM Disease mutations131965
Blocks (Seattle)METTL6
SuperfamilyQ8TCB7
Human Protein AtlasENSG00000206562
Peptide AtlasQ8TCB7
HPRD14494
IPIIPI00174125   IPI00376492   IPI00927648   IPI00927185   IPI00926819   
Protein Interaction databases
DIP (DOE-UCLA)Q8TCB7
IntAct (EBI)Q8TCB7
FunCoupENSG00000206562
BioGRIDMETTL6
STRING (EMBL)METTL6
ZODIACMETTL6
Ontologies - Pathways
QuickGOQ8TCB7
Ontology : AmiGOmethyltransferase activity  methylation  
Ontology : EGO-EBImethyltransferase activity  methylation  
Pathways : KEGGHistidine metabolism    Tyrosine metabolism   
NDEx NetworkMETTL6
Atlas of Cancer Signalling NetworkMETTL6
Wikipedia pathwaysMETTL6
Orthology - Evolution
OrthoDB131965
GeneTree (enSembl)ENSG00000206562
Phylogenetic Trees/Animal Genes : TreeFamMETTL6
HOVERGENQ8TCB7
HOGENOMQ8TCB7
Homologs : HomoloGeneMETTL6
Homology/Alignments : Family Browser (UCSC)METTL6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMETTL6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)METTL6
dbVarMETTL6
ClinVarMETTL6
1000_GenomesMETTL6 
Exome Variant ServerMETTL6
ExAC (Exome Aggregation Consortium)METTL6 (select the gene name)
Genetic variants : HAPMAP131965
Genomic Variants (DGV)METTL6 [DGVbeta]
DECIPHER (Syndromes)3:15451267-15469054  ENSG00000206562
CONAN: Copy Number AnalysisMETTL6 
Mutations
ICGC Data PortalMETTL6 
TCGA Data PortalMETTL6 
Broad Tumor PortalMETTL6
OASIS PortalMETTL6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMETTL6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMETTL6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch METTL6
DgiDB (Drug Gene Interaction Database)METTL6
DoCM (Curated mutations)METTL6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)METTL6 (select a term)
intoGenMETTL6
Cancer3DMETTL6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenMETTL6
Genetic Testing Registry METTL6
NextProtQ8TCB7 [Medical]
TSGene131965
GENETestsMETTL6
Huge Navigator METTL6 [HugePedia]
snp3D : Map Gene to Disease131965
BioCentury BCIQMETTL6
ClinGenMETTL6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD131965
Chemical/Pharm GKB GenePA142671462
Clinical trialMETTL6
Miscellaneous
canSAR (ICR)METTL6 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMETTL6
EVEXMETTL6
GoPubMedMETTL6
iHOPMETTL6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:28:07 CET 2017

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