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METTL8 (methyltransferase like 8)

Identity

Alias_symbol (synonym)FLJ13984
TIP
Other alias
HGNC (Hugo) METTL8
LocusID (NCBI) 79828
Atlas_Id 68929
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 171315746 and ends at 171434109 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MCEE (2p13.3) / METTL8 (2q31.1)METTL8 (2q31.1) / RALGAPA2 (20p11.23)METTL8 (2q31.1) / RFTN2 (2q33.1)
OLA1 (2q31.1) / METTL8 (2q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)METTL8   25856
Cards
Entrez_Gene (NCBI)METTL8  79828  methyltransferase like 8
AliasesTIP
GeneCards (Weizmann)METTL8
Ensembl hg19 (Hinxton)ENSG00000123600 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123600 [Gene_View]  chr2:171315746-171434109 [Contig_View]  METTL8 [Vega]
ICGC DataPortalENSG00000123600
TCGA cBioPortalMETTL8
AceView (NCBI)METTL8
Genatlas (Paris)METTL8
WikiGenes79828
SOURCE (Princeton)METTL8
Genetics Home Reference (NIH)METTL8
Genomic and cartography
GoldenPath hg38 (UCSC)METTL8  -     chr2:171315746-171434109 -  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)METTL8  -     2q31.1   [Description]    (hg19-Feb_2009)
EnsemblMETTL8 - 2q31.1 [CytoView hg19]  METTL8 - 2q31.1 [CytoView hg38]
Mapping of homologs : NCBIMETTL8 [Mapview hg19]  METTL8 [Mapview hg38]
OMIM609525   
Gene and transcription
Genbank (Entrez)AI129960 AK023396 AK024046 AK055616 AK093218
RefSeq transcript (Entrez)NM_001321154 NM_001321155 NM_001321156 NM_001321157 NM_001321158 NM_001321159 NM_001321160 NM_001321161 NM_001321162 NM_024770
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)METTL8
Cluster EST : UnigeneHs.560775 [ NCBI ]
CGAP (NCI)Hs.560775
Alternative Splicing GalleryENSG00000123600
Gene ExpressionMETTL8 [ NCBI-GEO ]   METTL8 [ EBI - ARRAY_EXPRESS ]   METTL8 [ SEEK ]   METTL8 [ MEM ]
Gene Expression Viewer (FireBrowse)METTL8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79828
GTEX Portal (Tissue expression)METTL8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H825   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H825  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H825
Splice isoforms : SwissVarQ9H825
PhosPhoSitePlusQ9H825
Domains : Interpro (EBI)MeTrfase    SAM-dependent_MTases   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)METTL8
DMDM Disease mutations79828
Blocks (Seattle)METTL8
SuperfamilyQ9H825
Human Protein AtlasENSG00000123600
Peptide AtlasQ9H825
HPRD07845
IPIIPI00792367   IPI00746282   IPI00303423   IPI00894483   IPI00894362   IPI00894137   IPI00894019   IPI00917024   
Protein Interaction databases
DIP (DOE-UCLA)Q9H825
IntAct (EBI)Q9H825
FunCoupENSG00000123600
BioGRIDMETTL8
STRING (EMBL)METTL8
ZODIACMETTL8
Ontologies - Pathways
QuickGOQ9H825
Ontology : AmiGOnucleus  cytoplasm  methyltransferase activity  methylation  
Ontology : EGO-EBInucleus  cytoplasm  methyltransferase activity  methylation  
NDEx NetworkMETTL8
Atlas of Cancer Signalling NetworkMETTL8
Wikipedia pathwaysMETTL8
Orthology - Evolution
OrthoDB79828
GeneTree (enSembl)ENSG00000123600
Phylogenetic Trees/Animal Genes : TreeFamMETTL8
HOVERGENQ9H825
HOGENOMQ9H825
Homologs : HomoloGeneMETTL8
Homology/Alignments : Family Browser (UCSC)METTL8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMETTL8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)METTL8
dbVarMETTL8
ClinVarMETTL8
1000_GenomesMETTL8 
Exome Variant ServerMETTL8
ExAC (Exome Aggregation Consortium)METTL8 (select the gene name)
Genetic variants : HAPMAP79828
Genomic Variants (DGV)METTL8 [DGVbeta]
DECIPHERMETTL8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMETTL8 
Mutations
ICGC Data PortalMETTL8 
TCGA Data PortalMETTL8 
Broad Tumor PortalMETTL8
OASIS PortalMETTL8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMETTL8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMETTL8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch METTL8
DgiDB (Drug Gene Interaction Database)METTL8
DoCM (Curated mutations)METTL8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)METTL8 (select a term)
intoGenMETTL8
Cancer3DMETTL8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609525   
Orphanet
MedgenMETTL8
Genetic Testing Registry METTL8
NextProtQ9H825 [Medical]
TSGene79828
GENETestsMETTL8
Target ValidationMETTL8
Huge Navigator METTL8 [HugePedia]
snp3D : Map Gene to Disease79828
BioCentury BCIQMETTL8
ClinGenMETTL8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79828
Chemical/Pharm GKB GenePA145008118
Clinical trialMETTL8
Miscellaneous
canSAR (ICR)METTL8 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMETTL8
EVEXMETTL8
GoPubMedMETTL8
iHOPMETTL8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 18 13:27:15 CEST 2017

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