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METTL8 (methyltransferase 8, methylcytidine)

Identity

Alias (NCBI)TIP
HGNC (Hugo) METTL8
HGNC Alias symbFLJ13984
TIP
HGNC Alias nametension-induced/inhibited protein
LocusID (NCBI) 79828
Atlas_Id 68929
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 171315746 and ends at 171434803 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MCEE (2p13.3) / METTL8 (2q31.1)METTL8 (2q31.1) / RALGAPA2 (20p11.23)METTL8 (2q31.1) / RFTN2 (2q33.1)
OLA1 (2q31.1) / METTL8 (2q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)METTL8   25856
Cards
Entrez_Gene (NCBI)METTL8    methyltransferase 8, methylcytidine
AliasesTIP
GeneCards (Weizmann)METTL8
Ensembl hg19 (Hinxton)ENSG00000123600 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123600 [Gene_View]  ENSG00000123600 [Sequence]  chr2:171315746-171434803 [Contig_View]  METTL8 [Vega]
ICGC DataPortalENSG00000123600
TCGA cBioPortalMETTL8
AceView (NCBI)METTL8
Genatlas (Paris)METTL8
SOURCE (Princeton)METTL8
Genetics Home Reference (NIH)METTL8
Genomic and cartography
GoldenPath hg38 (UCSC)METTL8  -     chr2:171315746-171434803 -  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)METTL8  -     2q31.1   [Description]    (hg19-Feb_2009)
GoldenPathMETTL8 - 2q31.1 [CytoView hg19]  METTL8 - 2q31.1 [CytoView hg38]
ImmunoBaseENSG00000123600
Genome Data Viewer NCBIMETTL8 [Mapview hg19]  
OMIM609525   
Gene and transcription
Genbank (Entrez)AI129960 AK023396 AK024046 AK055616 AK093218
RefSeq transcript (Entrez)NM_001321154 NM_001321155 NM_001321156 NM_001321157 NM_001321158 NM_001321159 NM_001321160 NM_001321161 NM_001321162 NM_024770
Consensus coding sequences : CCDS (NCBI)METTL8
Gene ExpressionMETTL8 [ NCBI-GEO ]   METTL8 [ EBI - ARRAY_EXPRESS ]   METTL8 [ SEEK ]   METTL8 [ MEM ]
Gene Expression Viewer (FireBrowse)METTL8 [ Firebrowse - Broad ]
GenevisibleExpression of METTL8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79828
GTEX Portal (Tissue expression)METTL8
Human Protein AtlasENSG00000123600-METTL8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H825   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H825  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H825
PhosPhoSitePlusQ9H825
Domains : Interpro (EBI)Methyltransf_25    MeTrfase    SAM-dependent_MTases   
Domain families : Pfam (Sanger)Methyltransf_25 (PF13649)   
Domain families : Pfam (NCBI)pfam13649   
Conserved Domain (NCBI)METTL8
SuperfamilyQ9H825
AlphaFold pdb e-kbQ9H825   
Human Protein Atlas [tissue]ENSG00000123600-METTL8 [tissue]
HPRD07845
Protein Interaction databases
DIP (DOE-UCLA)Q9H825
IntAct (EBI)Q9H825
BioGRIDMETTL8
STRING (EMBL)METTL8
ZODIACMETTL8
Ontologies - Pathways
QuickGOQ9H825
Ontology : AmiGOnucleus  cytoplasm  mRNA methyltransferase activity  tRNA methylation  tRNA (cytosine-3-)-methyltransferase activity  mRNA methylation  
Ontology : EGO-EBInucleus  cytoplasm  mRNA methyltransferase activity  tRNA methylation  tRNA (cytosine-3-)-methyltransferase activity  mRNA methylation  
NDEx NetworkMETTL8
Atlas of Cancer Signalling NetworkMETTL8
Wikipedia pathwaysMETTL8
Orthology - Evolution
OrthoDB79828
GeneTree (enSembl)ENSG00000123600
Phylogenetic Trees/Animal Genes : TreeFamMETTL8
Homologs : HomoloGeneMETTL8
Homology/Alignments : Family Browser (UCSC)METTL8
Gene fusions - Rearrangements
Fusion : QuiverMETTL8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMETTL8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)METTL8
dbVarMETTL8
ClinVarMETTL8
MonarchMETTL8
1000_GenomesMETTL8 
Exome Variant ServerMETTL8
GNOMAD BrowserENSG00000123600
Varsome BrowserMETTL8
ACMGMETTL8 variants
VarityQ9H825
Genomic Variants (DGV)METTL8 [DGVbeta]
DECIPHERMETTL8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMETTL8 
Mutations
ICGC Data PortalMETTL8 
TCGA Data PortalMETTL8 
Broad Tumor PortalMETTL8
OASIS PortalMETTL8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMETTL8  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMETTL8
Mutations and Diseases : HGMDMETTL8
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMETTL8
DgiDB (Drug Gene Interaction Database)METTL8
DoCM (Curated mutations)METTL8
CIViC (Clinical Interpretations of Variants in Cancer)METTL8
Cancer3DMETTL8
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609525   
Orphanet
DisGeNETMETTL8
MedgenMETTL8
Genetic Testing Registry METTL8
NextProtQ9H825 [Medical]
GENETestsMETTL8
Target ValidationMETTL8
Huge Navigator METTL8 [HugePedia]
ClinGenMETTL8
Clinical trials, drugs, therapy
MyCancerGenomeMETTL8
Protein Interactions : CTDMETTL8
Pharm GKB GenePA145008118
PharosQ9H825
Clinical trialMETTL8
Miscellaneous
canSAR (ICR)METTL8
HarmonizomeMETTL8
DataMed IndexMETTL8
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMETTL8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:07:12 CEST 2021

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