Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MEX3D (mex-3 RNA binding family member D)

Identity

Alias_namesRKHD1
ring finger and KH domain containing 1
mex-3 homolog D (C. elegans)
Alias_symbol (synonym)Tino
KIAA2031
OK/SW-cl.4
RNF193
Other aliasMEX-3D
MEX3
TINO
HGNC (Hugo) MEX3D
LocusID (NCBI) 399664
Atlas_Id 47199
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 1554669 and ends at 1568058 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MEX3D (19p13.3) / DCTN6 (8p12)MEX3D 19p13.3 / DCTN6 8p12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MEX3D   16734
Cards
Entrez_Gene (NCBI)MEX3D  399664  mex-3 RNA binding family member D
AliasesMEX-3D; MEX3; OK/SW-cl.4; RKHD1; 
RNF193; TINO
GeneCards (Weizmann)MEX3D
Ensembl hg19 (Hinxton)ENSG00000181588 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000181588 [Gene_View]  chr19:1554669-1568058 [Contig_View]  MEX3D [Vega]
ICGC DataPortalENSG00000181588
TCGA cBioPortalMEX3D
AceView (NCBI)MEX3D
Genatlas (Paris)MEX3D
WikiGenes399664
SOURCE (Princeton)MEX3D
Genetics Home Reference (NIH)MEX3D
Genomic and cartography
GoldenPath hg38 (UCSC)MEX3D  -     chr19:1554669-1568058 -  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MEX3D  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblMEX3D - 19p13.3 [CytoView hg19]  MEX3D - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIMEX3D [Mapview hg19]  MEX3D [Mapview hg38]
OMIM611009   
Gene and transcription
Genbank (Entrez)AB062435 AB107353 AF458084 AY950680 BC113384
RefSeq transcript (Entrez)NM_001174118 NM_203304
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MEX3D
Cluster EST : UnigeneHs.436495 [ NCBI ]
CGAP (NCI)Hs.436495
Alternative Splicing GalleryENSG00000181588
Gene ExpressionMEX3D [ NCBI-GEO ]   MEX3D [ EBI - ARRAY_EXPRESS ]   MEX3D [ SEEK ]   MEX3D [ MEM ]
Gene Expression Viewer (FireBrowse)MEX3D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)399664
GTEX Portal (Tissue expression)MEX3D
Human Protein AtlasENSG00000181588-MEX3D [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86XN8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86XN8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86XN8
Splice isoforms : SwissVarQ86XN8
PhosPhoSitePlusQ86XN8
Domaine pattern : Prosite (Expaxy)KH_TYPE_1 (PS50084)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)KH_dom    KH_dom_type_1    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)KH_1 (PF00013)   
Domain families : Pfam (NCBI)pfam00013   
Domain families : Smart (EMBL)KH (SM00322)  
Conserved Domain (NCBI)MEX3D
DMDM Disease mutations399664
Blocks (Seattle)MEX3D
PDB (SRS)2DGR   
PDB (PDBSum)2DGR   
PDB (IMB)2DGR   
PDB (RSDB)2DGR   
Structural Biology KnowledgeBase2DGR   
SCOP (Structural Classification of Proteins)2DGR   
CATH (Classification of proteins structures)2DGR   
SuperfamilyQ86XN8
Human Protein Atlas [tissue]ENSG00000181588-MEX3D [tissue]
Peptide AtlasQ86XN8
HPRD15254
IPIIPI00478085   IPI00655985   IPI00169380   IPI00783891   
Protein Interaction databases
DIP (DOE-UCLA)Q86XN8
IntAct (EBI)Q86XN8
FunCoupENSG00000181588
BioGRIDMEX3D
STRING (EMBL)MEX3D
ZODIACMEX3D
Ontologies - Pathways
QuickGOQ86XN8
Ontology : AmiGORNA binding  nucleus  zinc ion binding  mRNA localization resulting in posttranscriptional regulation of gene expression  AU-rich element binding  perinuclear region of cytoplasm  mRNA destabilization  
Ontology : EGO-EBIRNA binding  nucleus  zinc ion binding  mRNA localization resulting in posttranscriptional regulation of gene expression  AU-rich element binding  perinuclear region of cytoplasm  mRNA destabilization  
NDEx NetworkMEX3D
Atlas of Cancer Signalling NetworkMEX3D
Wikipedia pathwaysMEX3D
Orthology - Evolution
OrthoDB399664
GeneTree (enSembl)ENSG00000181588
Phylogenetic Trees/Animal Genes : TreeFamMEX3D
HOVERGENQ86XN8
HOGENOMQ86XN8
Homologs : HomoloGeneMEX3D
Homology/Alignments : Family Browser (UCSC)MEX3D
Gene fusions - Rearrangements
Fusion : MitelmanMEX3D/DCTN6 [19p13.3/8p12]  
Fusion: TCGA_MDACCMEX3D 19p13.3 DCTN6 8p12 BRCA
Tumor Fusion PortalMEX3D
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMEX3D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MEX3D
dbVarMEX3D
ClinVarMEX3D
1000_GenomesMEX3D 
Exome Variant ServerMEX3D
ExAC (Exome Aggregation Consortium)ENSG00000181588
GNOMAD BrowserENSG00000181588
Genetic variants : HAPMAP399664
Genomic Variants (DGV)MEX3D [DGVbeta]
DECIPHERMEX3D [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMEX3D 
Mutations
ICGC Data PortalMEX3D 
TCGA Data PortalMEX3D 
Broad Tumor PortalMEX3D
OASIS PortalMEX3D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMEX3D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMEX3D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MEX3D
DgiDB (Drug Gene Interaction Database)MEX3D
DoCM (Curated mutations)MEX3D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MEX3D (select a term)
intoGenMEX3D
Cancer3DMEX3D(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611009   
Orphanet
DisGeNETMEX3D
MedgenMEX3D
Genetic Testing Registry MEX3D
NextProtQ86XN8 [Medical]
TSGene399664
GENETestsMEX3D
Target ValidationMEX3D
Huge Navigator MEX3D [HugePedia]
snp3D : Map Gene to Disease399664
BioCentury BCIQMEX3D
ClinGenMEX3D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD399664
Chemical/Pharm GKB GenePA162395829
Clinical trialMEX3D
Miscellaneous
canSAR (ICR)MEX3D (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMEX3D
EVEXMEX3D
GoPubMedMEX3D
iHOPMEX3D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:22:13 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.