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MFHAS1 (malignant fibrous histiocytoma amplified sequence 1)

Identity

Alias_symbol (synonym)MASL1
LRRC65
Other aliasROCO4
HGNC (Hugo) MFHAS1
LocusID (NCBI) 9258
Atlas_Id 41343
Location 8p23.1  [Link to chromosome band 8p23]
Location_base_pair Starts at 8784489 and ends at 8893621 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DAAM1 (14q23.1) / MFHAS1 (8p23.1)GPR137B (1q42.3) / MFHAS1 (8p23.1)MFHAS1 (8p23.1) / DDX18 (2q14.1)
MFHAS1 (8p23.1) / FRMD4B (3p14.1)MFHAS1 (8p23.1) / UBAP1 (9p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MFHAS1   16982
Cards
Entrez_Gene (NCBI)MFHAS1  9258  malignant fibrous histiocytoma amplified sequence 1
AliasesLRRC65; MASL1; ROCO4
GeneCards (Weizmann)MFHAS1
Ensembl hg19 (Hinxton)ENSG00000147324 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147324 [Gene_View]  chr8:8784489-8893621 [Contig_View]  MFHAS1 [Vega]
ICGC DataPortalENSG00000147324
TCGA cBioPortalMFHAS1
AceView (NCBI)MFHAS1
Genatlas (Paris)MFHAS1
WikiGenes9258
SOURCE (Princeton)MFHAS1
Genetics Home Reference (NIH)MFHAS1
Genomic and cartography
GoldenPath hg38 (UCSC)MFHAS1  -     chr8:8784489-8893621 -  8p23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MFHAS1  -     8p23.1   [Description]    (hg19-Feb_2009)
EnsemblMFHAS1 - 8p23.1 [CytoView hg19]  MFHAS1 - 8p23.1 [CytoView hg38]
Mapping of homologs : NCBIMFHAS1 [Mapview hg19]  MFHAS1 [Mapview hg38]
OMIM605352   
Gene and transcription
Genbank (Entrez)AB016816 AK027007 AK096504 BC014226 BC167810
RefSeq transcript (Entrez)NM_004225
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MFHAS1
Cluster EST : UnigeneHs.379414 [ NCBI ]
CGAP (NCI)Hs.379414
Alternative Splicing GalleryENSG00000147324
Gene ExpressionMFHAS1 [ NCBI-GEO ]   MFHAS1 [ EBI - ARRAY_EXPRESS ]   MFHAS1 [ SEEK ]   MFHAS1 [ MEM ]
Gene Expression Viewer (FireBrowse)MFHAS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9258
GTEX Portal (Tissue expression)MFHAS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4C4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4C4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4C4
Splice isoforms : SwissVarQ9Y4C4
PhosPhoSitePlusQ9Y4C4
Domaine pattern : Prosite (Expaxy)LRR (PS51450)    ROC (PS51424)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    MIRO-like    P-loop_NTPase    ROC_dom   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    Roc (PF08477)   
Domain families : Pfam (NCBI)pfam13855    pfam08477   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  
Conserved Domain (NCBI)MFHAS1
DMDM Disease mutations9258
Blocks (Seattle)MFHAS1
SuperfamilyQ9Y4C4
Human Protein AtlasENSG00000147324
Peptide AtlasQ9Y4C4
HPRD12010
IPIIPI00003495   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4C4
IntAct (EBI)Q9Y4C4
FunCoupENSG00000147324
BioGRIDMFHAS1
STRING (EMBL)MFHAS1
ZODIACMFHAS1
Ontologies - Pathways
QuickGOQ9Y4C4
Ontology : AmiGOprotein binding  GTP binding  intracellular  plasma membrane  signal transduction  small GTPase mediated signal transduction  
Ontology : EGO-EBIprotein binding  GTP binding  intracellular  plasma membrane  signal transduction  small GTPase mediated signal transduction  
NDEx NetworkMFHAS1
Atlas of Cancer Signalling NetworkMFHAS1
Wikipedia pathwaysMFHAS1
Orthology - Evolution
OrthoDB9258
GeneTree (enSembl)ENSG00000147324
Phylogenetic Trees/Animal Genes : TreeFamMFHAS1
HOVERGENQ9Y4C4
HOGENOMQ9Y4C4
Homologs : HomoloGeneMFHAS1
Homology/Alignments : Family Browser (UCSC)MFHAS1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMFHAS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MFHAS1
dbVarMFHAS1
ClinVarMFHAS1
1000_GenomesMFHAS1 
Exome Variant ServerMFHAS1
ExAC (Exome Aggregation Consortium)MFHAS1 (select the gene name)
Genetic variants : HAPMAP9258
Genomic Variants (DGV)MFHAS1 [DGVbeta]
DECIPHERMFHAS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMFHAS1 
Mutations
ICGC Data PortalMFHAS1 
TCGA Data PortalMFHAS1 
Broad Tumor PortalMFHAS1
OASIS PortalMFHAS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMFHAS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMFHAS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MFHAS1
DgiDB (Drug Gene Interaction Database)MFHAS1
DoCM (Curated mutations)MFHAS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MFHAS1 (select a term)
intoGenMFHAS1
Cancer3DMFHAS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605352   
Orphanet
MedgenMFHAS1
Genetic Testing Registry MFHAS1
NextProtQ9Y4C4 [Medical]
TSGene9258
GENETestsMFHAS1
Target ValidationMFHAS1
Huge Navigator MFHAS1 [HugePedia]
snp3D : Map Gene to Disease9258
BioCentury BCIQMFHAS1
ClinGenMFHAS1 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9258
Chemical/Pharm GKB GenePA30773
Clinical trialMFHAS1
Miscellaneous
canSAR (ICR)MFHAS1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMFHAS1
EVEXMFHAS1
GoPubMedMFHAS1
iHOPMFHAS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:06:41 CEST 2017

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