MFSD2B (major facilitator superfamily domain containing 2B)

2014-11-01  

Identity

HGNC
MFSD2B
LOCATION
2p23.3
LOCUSID
388931
ALIAS
SLC59A2

Other Information

Locus ID:

NCBI: 388931
MIM: 617845
HGNC: 37207
Ensembl: ENSG00000205639

Variants:

dbSNP: 388931
ClinVar: 388931
TCGA: ENSG00000205639
COSMIC: MFSD2B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205639ENST00000338315A6NFX1
ENSG00000205639ENST00000406420A0A2I3JL00
ENSG00000205639ENST00000453731H7BZN4
ENSG00000205639ENST00000669179A0A590UK14

Expression (GTEx)

0
1
2
3
4
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
186943952008Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis.26
273019512016Variations of chromosome 2 gene expressions among patients with lung cancer or non-cancer.9
290453862017Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets.0
295635272018MFSD2B is a sphingosine 1-phosphate transporter in erythroid cells.0

Citation

Dessen P

MFSD2B (major facilitator superfamily domain containing 2B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68940/mfsd2b