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MGA (MGA, MAX dimerization protein)

Identity

Alias_namesMAX gene associated
Alias_symbol (synonym)KIAA0518
MAD5
MXD5
FLJ12634
Other alias
HGNC (Hugo) MGA
LocusID (NCBI) 23269
Atlas_Id 53659
Location 15q15.1  [Link to chromosome band 15q15]
Location_base_pair Starts at 41660412 and ends at 41769943 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CDKN2A (9p21.3) / MGA (15q15.1)MGA (15q15.1) / ANKLE1 (19p13.11)MGA (15q15.1) / CDKN2A (9p21.3)
MGA (15q15.1) / MGA (15q15.1)MGA (15q15.1) / PBX4 (19p13.11)MGA (15q15.1) / SCD (10q24.31)
MGA (15q15.1) / TMED7-TICAM2 (5q22.3)CDKN2A 9p21.3 / MGA 15q15.1MGA 15q15.1 / ANKLE1 19p13.11
MGA 15q15.1 / CDKN2A 9p21.3MGA 15q15.1 / PBX4 19p13.11MGA 15q15.1 / SCD 10q24.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MGA   14010
Cards
Entrez_Gene (NCBI)MGA  23269  MGA, MAX dimerization protein
AliasesMAD5; MXD5
GeneCards (Weizmann)MGA
Ensembl hg19 (Hinxton)ENSG00000174197 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174197 [Gene_View]  chr15:41660412-41769943 [Contig_View]  MGA [Vega]
ICGC DataPortalENSG00000174197
TCGA cBioPortalMGA
AceView (NCBI)MGA
Genatlas (Paris)MGA
WikiGenes23269
SOURCE (Princeton)MGA
Genetics Home Reference (NIH)MGA
Genomic and cartography
GoldenPath hg38 (UCSC)MGA  -     chr15:41660412-41769943 +  15q15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MGA  -     15q15.1   [Description]    (hg19-Feb_2009)
EnsemblMGA - 15q15.1 [CytoView hg19]  MGA - 15q15.1 [CytoView hg38]
Mapping of homologs : NCBIMGA [Mapview hg19]  MGA [Mapview hg38]
OMIM616061   
Gene and transcription
Genbank (Entrez)AA188751 AB011090 AI434570 AK022696 AK023360
RefSeq transcript (Entrez)NM_001080541 NM_001164273
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MGA
Cluster EST : UnigeneHs.187569 [ NCBI ]
CGAP (NCI)Hs.187569
Alternative Splicing GalleryENSG00000174197
Gene ExpressionMGA [ NCBI-GEO ]   MGA [ EBI - ARRAY_EXPRESS ]   MGA [ SEEK ]   MGA [ MEM ]
Gene Expression Viewer (FireBrowse)MGA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23269
GTEX Portal (Tissue expression)MGA
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IWI9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IWI9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IWI9
Splice isoforms : SwissVarQ8IWI9
PhosPhoSitePlusQ8IWI9
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)    TBOX_2 (PS01264)    TBOX_3 (PS50252)   
Domains : Interpro (EBI)bHLH_dom    DUF4801    p53-like_TF_DNA-bd    TF_T-box    TF_T-box_CS   
Domain families : Pfam (Sanger)DUF4801 (PF16059)    HLH (PF00010)    T-box (PF00907)   
Domain families : Pfam (NCBI)pfam16059    pfam00010    pfam00907   
Domain families : Smart (EMBL)HLH (SM00353)  TBOX (SM00425)  
Conserved Domain (NCBI)MGA
DMDM Disease mutations23269
Blocks (Seattle)MGA
SuperfamilyQ8IWI9
Human Protein AtlasENSG00000174197
Peptide AtlasQ8IWI9
IPIIPI01009835   IPI00741005   IPI00943971   
Protein Interaction databases
DIP (DOE-UCLA)Q8IWI9
IntAct (EBI)Q8IWI9
FunCoupENSG00000174197
BioGRIDMGA
STRING (EMBL)MGA
ZODIACMGA
Ontologies - Pathways
QuickGOQ8IWI9
Ontology : AmiGODNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  transcription, DNA-templated  regulation of transcription, DNA-templated  protein dimerization activity  MLL1 complex  
Ontology : EGO-EBIDNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  transcription, DNA-templated  regulation of transcription, DNA-templated  protein dimerization activity  MLL1 complex  
NDEx NetworkMGA
Atlas of Cancer Signalling NetworkMGA
Wikipedia pathwaysMGA
Orthology - Evolution
OrthoDB23269
GeneTree (enSembl)ENSG00000174197
Phylogenetic Trees/Animal Genes : TreeFamMGA
HOVERGENQ8IWI9
HOGENOMQ8IWI9
Homologs : HomoloGeneMGA
Homology/Alignments : Family Browser (UCSC)MGA
Gene fusions - Rearrangements
Fusion : MitelmanCDKN2A/MGA [9p21.3/15q15.1]  [t(9;15)(p21;q15)]  
Fusion : MitelmanMGA/ANKLE1 [15q15.1/19p13.11]  [t(15;19)(q15;p13)]  
Fusion : MitelmanMGA/CDKN2A [15q15.1/9p21.3]  [t(9;15)(p21;q15)]  
Fusion : MitelmanMGA/PBX4 [15q15.1/19p13.11]  [t(15;19)(q15;p13)]  
Fusion : MitelmanMGA/SCD [15q15.1/10q24.31]  [t(10;15)(q24;q15)]  
Fusion: TCGACDKN2A 9p21.3 MGA 15q15.1 BLCA
Fusion: TCGAMGA 15q15.1 ANKLE1 19p13.11 LUAD
Fusion: TCGAMGA 15q15.1 CDKN2A 9p21.3 BLCA
Fusion: TCGAMGA 15q15.1 PBX4 19p13.11 LUAD
Fusion: TCGAMGA 15q15.1 SCD 10q24.31 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMGA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MGA
dbVarMGA
ClinVarMGA
1000_GenomesMGA 
Exome Variant ServerMGA
ExAC (Exome Aggregation Consortium)MGA (select the gene name)
Genetic variants : HAPMAP23269
Genomic Variants (DGV)MGA [DGVbeta]
DECIPHERMGA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMGA 
Mutations
ICGC Data PortalMGA 
TCGA Data PortalMGA 
Broad Tumor PortalMGA
OASIS PortalMGA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMGA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMGA
intOGen PortalMGA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MGA
DgiDB (Drug Gene Interaction Database)MGA
DoCM (Curated mutations)MGA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MGA (select a term)
intoGenMGA
Cancer3DMGA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616061   
Orphanet
MedgenMGA
Genetic Testing Registry MGA
NextProtQ8IWI9 [Medical]
TSGene23269
GENETestsMGA
Target ValidationMGA
Huge Navigator MGA [HugePedia]
snp3D : Map Gene to Disease23269
BioCentury BCIQMGA
ClinGenMGA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23269
Chemical/Pharm GKB GenePA134976336
Clinical trialMGA
Miscellaneous
canSAR (ICR)MGA (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMGA
EVEXMGA
GoPubMedMGA
iHOPMGA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:42:54 CEST 2017

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