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MGAM (maltase-glucoamylase)

Identity

Alias_symbol (synonym)MGA
Other aliasMG
HGNC (Hugo) MGAM
LocusID (NCBI) 8972
Atlas_Id 68948
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 141995879 and ends at 142106747 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MGAM   7043
Cards
Entrez_Gene (NCBI)MGAM  8972  maltase-glucoamylase
AliasesMG; MGA
GeneCards (Weizmann)MGAM
Ensembl hg19 (Hinxton)ENSG00000257335 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000257335 [Gene_View]  chr7:141995879-142106747 [Contig_View]  MGAM [Vega]
ICGC DataPortalENSG00000257335
TCGA cBioPortalMGAM
AceView (NCBI)MGAM
Genatlas (Paris)MGAM
WikiGenes8972
SOURCE (Princeton)MGAM
Genetics Home Reference (NIH)MGAM
Genomic and cartography
GoldenPath hg38 (UCSC)MGAM  -     chr7:141995879-142106747 +  7q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MGAM  -     7q34   [Description]    (hg19-Feb_2009)
EnsemblMGAM - 7q34 [CytoView hg19]  MGAM - 7q34 [CytoView hg38]
Mapping of homologs : NCBIMGAM [Mapview hg19]  MGAM [Mapview hg38]
OMIM154360   
Gene and transcription
Genbank (Entrez)AF016833 AK127838 BC120872
RefSeq transcript (Entrez)NM_004668
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_033954 NT_187562
Consensus coding sequences : CCDS (NCBI)MGAM
Cluster EST : UnigeneHs.122785 [ NCBI ]
CGAP (NCI)Hs.122785
Alternative Splicing GalleryENSG00000257335
Gene ExpressionMGAM [ NCBI-GEO ]   MGAM [ EBI - ARRAY_EXPRESS ]   MGAM [ SEEK ]   MGAM [ MEM ]
Gene Expression Viewer (FireBrowse)MGAM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8972
GTEX Portal (Tissue expression)MGAM
Human Protein AtlasENSG00000257335-MGAM [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43451   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43451  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43451
Splice isoforms : SwissVarO43451
Catalytic activity : Enzyme3.2.1.20 [ Enzyme-Expasy ]   3.2.1.203.2.1.20 [ IntEnz-EBI ]   3.2.1.20 [ BRENDA ]   3.2.1.20 [ KEGG ]   
PhosPhoSitePlusO43451
Domaine pattern : Prosite (Expaxy)GLYCOSYL_HYDROL_F31_1 (PS00129)    GLYCOSYL_HYDROL_F31_2 (PS00707)    P_TREFOIL_1 (PS00025)    P_TREFOIL_2 (PS51448)   
Domains : Interpro (EBI)Gal_mutarotase_N    Gal_mutarotase_SF_dom    Glyco_hydro_31    Glyco_hydro_31_AS    Glyco_hydro_31_CS    Glycoside_hydrolase_SF    P_trefoil_CS    P_trefoil_dom   
Domain families : Pfam (Sanger)Glyco_hydro_31 (PF01055)    NtCtMGAM_N (PF16863)    Trefoil (PF00088)   
Domain families : Pfam (NCBI)pfam01055    pfam16863    pfam00088   
Domain families : Smart (EMBL)PD (SM00018)  
Conserved Domain (NCBI)MGAM
DMDM Disease mutations8972
Blocks (Seattle)MGAM
PDB (SRS)2QLY    2QMJ    3CTT    3L4T    3L4U    3L4V    3L4W    3L4X    3L4Y    3L4Z    3TON    3TOP   
PDB (PDBSum)2QLY    2QMJ    3CTT    3L4T    3L4U    3L4V    3L4W    3L4X    3L4Y    3L4Z    3TON    3TOP   
PDB (IMB)2QLY    2QMJ    3CTT    3L4T    3L4U    3L4V    3L4W    3L4X    3L4Y    3L4Z    3TON    3TOP   
PDB (RSDB)2QLY    2QMJ    3CTT    3L4T    3L4U    3L4V    3L4W    3L4X    3L4Y    3L4Z    3TON    3TOP   
Structural Biology KnowledgeBase2QLY    2QMJ    3CTT    3L4T    3L4U    3L4V    3L4W    3L4X    3L4Y    3L4Z    3TON    3TOP   
SCOP (Structural Classification of Proteins)2QLY    2QMJ    3CTT    3L4T    3L4U    3L4V    3L4W    3L4X    3L4Y    3L4Z    3TON    3TOP   
CATH (Classification of proteins structures)2QLY    2QMJ    3CTT    3L4T    3L4U    3L4V    3L4W    3L4X    3L4Y    3L4Z    3TON    3TOP   
SuperfamilyO43451
Human Protein Atlas [tissue]ENSG00000257335-MGAM [tissue]
Peptide AtlasO43451
HPRD01104
IPIIPI00220143   IPI00945229   IPI00947365   IPI00947031   
Protein Interaction databases
DIP (DOE-UCLA)O43451
IntAct (EBI)O43451
FunCoupENSG00000257335
BioGRIDMGAM
STRING (EMBL)MGAM
ZODIACMGAM
Ontologies - Pathways
QuickGOO43451
Ontology : AmiGOmaltose metabolic process  catalytic activity  glucan 1,4-alpha-glucosidase activity  alpha-1,4-glucosidase activity  plasma membrane  starch catabolic process  integral component of membrane  amylase activity  apical plasma membrane  carbohydrate binding  maltose alpha-glucosidase activity  neutrophil degranulation  polysaccharide digestion  extracellular exosome  tertiary granule membrane  ficolin-1-rich granule membrane  
Ontology : EGO-EBImaltose metabolic process  catalytic activity  glucan 1,4-alpha-glucosidase activity  alpha-1,4-glucosidase activity  plasma membrane  starch catabolic process  integral component of membrane  amylase activity  apical plasma membrane  carbohydrate binding  maltose alpha-glucosidase activity  neutrophil degranulation  polysaccharide digestion  extracellular exosome  tertiary granule membrane  ficolin-1-rich granule membrane  
Pathways : KEGGGalactose metabolism    Starch and sucrose metabolism    Carbohydrate digestion and absorption   
NDEx NetworkMGAM
Atlas of Cancer Signalling NetworkMGAM
Wikipedia pathwaysMGAM
Orthology - Evolution
OrthoDB8972
GeneTree (enSembl)ENSG00000257335
Phylogenetic Trees/Animal Genes : TreeFamMGAM
HOVERGENO43451
HOGENOMO43451
Homologs : HomoloGeneMGAM
Homology/Alignments : Family Browser (UCSC)MGAM
Gene fusions - Rearrangements
Tumor Fusion PortalMGAM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMGAM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MGAM
dbVarMGAM
ClinVarMGAM
1000_GenomesMGAM 
Exome Variant ServerMGAM
ExAC (Exome Aggregation Consortium)ENSG00000257335
GNOMAD BrowserENSG00000257335
Genetic variants : HAPMAP8972
Genomic Variants (DGV)MGAM [DGVbeta]
DECIPHERMGAM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMGAM 
Mutations
ICGC Data PortalMGAM 
TCGA Data PortalMGAM 
Broad Tumor PortalMGAM
OASIS PortalMGAM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMGAM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMGAM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MGAM
DgiDB (Drug Gene Interaction Database)MGAM
DoCM (Curated mutations)MGAM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MGAM (select a term)
intoGenMGAM
Cancer3DMGAM(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM154360   
Orphanet
DisGeNETMGAM
MedgenMGAM
Genetic Testing Registry MGAM
NextProtO43451 [Medical]
TSGene8972
GENETestsMGAM
Target ValidationMGAM
Huge Navigator MGAM [HugePedia]
snp3D : Map Gene to Disease8972
BioCentury BCIQMGAM
ClinGenMGAM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8972
Chemical/Pharm GKB GenePA30778
Clinical trialMGAM
Miscellaneous
canSAR (ICR)MGAM (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMGAM
EVEXMGAM
GoPubMedMGAM
iHOPMGAM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:16:32 CET 2017

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