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MGP (matrix Gla protein)

Identity

Other aliasGIG36
MGLAP
NTI
HGNC (Hugo) MGP
LocusID (NCBI) 4256
Atlas_Id 54454
Location 12p12.3  [Link to chromosome band 12p12]
Location_base_pair Starts at 15034115 and ends at 15038853 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ASB5 (4q34.2) / MGP (12p12.3)CALM1 (14q32.11) / MGP (12p12.3)MGP (12p12.3) / LRRC75A-AS1 (17p11.2)
MGP (12p12.3) / REPS2 (Xp22.2)MYCL (1p34.2) / MGP (12p12.3)PRSS23 (11q14.2) / MGP (12p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MGP   7060
Cards
Entrez_Gene (NCBI)MGP  4256  matrix Gla protein
AliasesGIG36; MGLAP; NTI
GeneCards (Weizmann)MGP
Ensembl hg19 (Hinxton)ENSG00000111341 [Gene_View]  chr12:15034115-15038853 [Contig_View]  MGP [Vega]
Ensembl hg38 (Hinxton)ENSG00000111341 [Gene_View]  chr12:15034115-15038853 [Contig_View]  MGP [Vega]
ICGC DataPortalENSG00000111341
TCGA cBioPortalMGP
AceView (NCBI)MGP
Genatlas (Paris)MGP
WikiGenes4256
SOURCE (Princeton)MGP
Genetics Home Reference (NIH)MGP
Genomic and cartography
GoldenPath hg19 (UCSC)MGP  -     chr12:15034115-15038853 -  12p12.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MGP  -     12p12.3   [Description]    (hg38-Dec_2013)
EnsemblMGP - 12p12.3 [CytoView hg19]  MGP - 12p12.3 [CytoView hg38]
Mapping of homologs : NCBIMGP [Mapview hg19]  MGP [Mapview hg38]
OMIM154870   245150   
Gene and transcription
Genbank (Entrez)AK310040 AK312029 AW997681 AY542304 BC005272
RefSeq transcript (Entrez)NM_000900 NM_001190839
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_023331 NT_009714 NW_004929383
Consensus coding sequences : CCDS (NCBI)MGP
Cluster EST : UnigeneHs.365706 [ NCBI ]
CGAP (NCI)Hs.365706
Alternative Splicing GalleryENSG00000111341
Gene ExpressionMGP [ NCBI-GEO ]   MGP [ EBI - ARRAY_EXPRESS ]   MGP [ SEEK ]   MGP [ MEM ]
Gene Expression Viewer (FireBrowse)MGP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4256
GTEX Portal (Tissue expression)MGP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08493   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08493  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08493
Splice isoforms : SwissVarP08493
PhosPhoSitePlusP08493
Domaine pattern : Prosite (Expaxy)GLA_1 (PS00011)    GLA_2 (PS50998)   
Domains : Interpro (EBI)GLA_domain    MGP    Osteocalcin/MGP   
Domain families : Pfam (Sanger)Gla (PF00594)   
Domain families : Pfam (NCBI)pfam00594   
Domain families : Smart (EMBL)GLA (SM00069)  
Conserved Domain (NCBI)MGP
DMDM Disease mutations4256
Blocks (Seattle)MGP
SuperfamilyP08493
Human Protein AtlasENSG00000111341
Peptide AtlasP08493
HPRD01112
IPIIPI00028714   IPI01015906   IPI00981924   
Protein Interaction databases
DIP (DOE-UCLA)P08493
IntAct (EBI)P08493
FunCoupENSG00000111341
BioGRIDMGP
STRING (EMBL)MGP
ZODIACMGP
Ontologies - Pathways
QuickGOP08493
Ontology : AmiGOcartilage condensation  ossification  extracellular matrix structural constituent  calcium ion binding  protein binding  proteinaceous extracellular matrix  structural constituent of bone  cell differentiation  regulation of bone mineralization  extracellular matrix  extracellular exosome  
Ontology : EGO-EBIcartilage condensation  ossification  extracellular matrix structural constituent  calcium ion binding  protein binding  proteinaceous extracellular matrix  structural constituent of bone  cell differentiation  regulation of bone mineralization  extracellular matrix  extracellular exosome  
NDEx NetworkMGP
Atlas of Cancer Signalling NetworkMGP
Wikipedia pathwaysMGP
Orthology - Evolution
OrthoDB4256
GeneTree (enSembl)ENSG00000111341
Phylogenetic Trees/Animal Genes : TreeFamMGP
HOVERGENP08493
HOGENOMP08493
Homologs : HomoloGeneMGP
Homology/Alignments : Family Browser (UCSC)MGP
Gene fusions - Rearrangements
Fusion : MitelmanMGP/LRRC75A-AS1 [12p12.3/17p11.2]  
Fusion : MitelmanMGP/REPS2 [12p12.3/Xp22.2]  [t(X;12)(p22;p12)]  
Fusion Cancer (Beijing)MYCL1 [MGP]  -  12p12.3 [FUSC002514]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMGP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MGP
dbVarMGP
ClinVarMGP
1000_GenomesMGP 
Exome Variant ServerMGP
ExAC (Exome Aggregation Consortium)MGP (select the gene name)
Genetic variants : HAPMAP4256
Genomic Variants (DGV)MGP [DGVbeta]
DECIPHER (Syndromes)12:15034115-15038853  ENSG00000111341
CONAN: Copy Number AnalysisMGP 
Mutations
ICGC Data PortalMGP 
TCGA Data PortalMGP 
Broad Tumor PortalMGP
OASIS PortalMGP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMGP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMGP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MGP
DgiDB (Drug Gene Interaction Database)MGP
DoCM (Curated mutations)MGP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MGP (select a term)
intoGenMGP
Cancer3DMGP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM154870    245150   
Orphanet11660   
MedgenMGP
Genetic Testing Registry MGP
NextProtP08493 [Medical]
TSGene4256
GENETestsMGP
Huge Navigator MGP [HugePedia]
snp3D : Map Gene to Disease4256
BioCentury BCIQMGP
ClinGenMGP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4256
Chemical/Pharm GKB GenePA30790
Clinical trialMGP
Miscellaneous
canSAR (ICR)MGP (select the gene name)
Probes
Litterature
PubMed97 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMGP
EVEXMGP
GoPubMedMGP
iHOPMGP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:15:08 CET 2017

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